Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Federica Franciosa"'
Autor:
Rahul Dhandapani, Cynthia Mary Arokiaraj, Francisco J. Taberner, Paola Pacifico, Sruthi Raja, Linda Nocchi, Carla Portulano, Federica Franciosa, Mariano Maffei, Ahmad Fawzi Hussain, Fernanda de Castro Reis, Luc Reymond, Emerald Perlas, Simone Garcovich, Stefan Barth, Kai Johnsson, Stefan G. Lechner, Paul A. Heppenstall
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
There are several classes of sensory neuron that contribute to pain states. Here, the authors demonstrate that TrkB+ sensory neurons detect light touch under normal conditions in mice but contribute to hypersensitivity in models of chronic pain, and
Externí odkaz:
https://doaj.org/article/fe4dc2a3ccaf4f5496713ff8538a5861
Autor:
Mariano Maffei, A. Gargano, Paul A. Heppenstall, Carla Portulano, Linda Nocchi, M. Panea, Balint Doleschall, Federica Franciosa, Emerald Perlas, Nainika Roy
Nerve growth factor (NGF) and its receptors TrkA and p75 play a key role in the development and function of peripheral nociceptive neurons. Here we describe novel technology to selectively photoablate TrkA positive nociceptors through delivery of a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29b1b563b3fed4dd442acd3edb45ead
https://doi.org/10.1101/575274
https://doi.org/10.1101/575274
Autor:
Emerald Perlas, Mirela Panea, Balint Doleschall, Mariano Maffei, Linda Nocchi, Federica Franciosa, Carla Portulano, Alessandra Gargano, Paul A. Heppenstall, Nainika Roy
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. A ligand-guided, light-activated photosensitizer tool targets TrkA-expressing nociceptors, reversing acute and chronic pain in mice.
Nerve growth factor (NGF) and its receptors TrkA and p75
Nerve growth factor (NGF) and its receptors TrkA and p75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ecfff7d919e50b6c09ce0c24bfb441
http://hdl.handle.net/20.500.11767/108823
http://hdl.handle.net/20.500.11767/108823
Autor:
Federica Franciosa, Francisco J. Taberner, Carla Portulano, Simone Garcovich, Mariano Maffei, Paul A. Heppenstall, Stefan Barth, Rahul Dhandapani, Sruthi Raja, Linda Nocchi, Paola Pacifico, Fernanda de Castro Reis, Emerald Perlas, Luc Reymond, Ahmad Fawzi Hussain, Kai Johnsson, Stefan G. Lechner, Cynthia Mary Arokiaraj
SummaryMechanical allodynia is a major symptom of neuropathic pain whereby innocuous touch evokes severe pain. Here we identify a population of peripheral sensory neurons expressing TrkB that are both necessary and sufficient for producing pain from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea066c32dfc1af5b3885a1643385a555