Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Federica Di Marcello"'
Autor:
Rino Rappuoli, Enrico Balducci, Mariangela Del Vecchio, Mariagrazia Pizza, Nathalie Norais, Massimiliano Biagini, Federica Di Marcello, Monica Picchianti, Daniele Veggi
Publikováno v:
The FASEB Journal. 27:4723-4730
NarE is an arginine-specific mono-ADP-ribosyltransferase identified in Neisseria meningitidis that requires the presence of iron in a structured cluster for its enzymatic activities. In this study, we show that NarE can perform auto-ADP-ribosylation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff5af8fe5eed5043c02ee8cc7f21a2e
https://doi.org/10.1096/fj.13-229955
https://doi.org/10.1096/fj.13-229955
Autor:
Federica Di Marcello, Gabriella Jacomelli, G. Pompucci, Matteo Bertelli, Vanna Micheli, L. Notarantonio, Hyder A. Jinnah, Barbara Cerboni, Silvia Sestini
Publikováno v:
Metabolic Brain Disease. 24:311-319
The activity of hypoxanthine-guanine phosphoribosyltransferase (HPRT) is virtually absent in Lesch-Nyhan disease (LND), an X-linked genetic disorder characterized by uric acid accumulation and neurodevelopmental dysfunction. The biochemical basis for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99e47ba1ada6f72a09e55436e4add4a
https://doi.org/10.1007/s11011-009-9134-9
https://doi.org/10.1007/s11011-009-9134-9
Autor:
Maurizio Comanducci, Claudio Donati, Giacomo Romagnoli, Daniele Veggi, Mariagrazia Pizza, Rino Rappuoli, Laura Santini, Silvana Savino, Marzia Monica Giuliani, Maria Scarselli, Federica Di Marcello, Sara Dragonetti, Lucia Banci, Francesca Cantini
Publikováno v:
Journal of Molecular Biology. 386:97-108
The factor H binding protein (fHbp) is a 27-kDa membrane-anchored lipoprotein of Neisseria meningitidis that allows the survival of the bacterium in human plasma; it is also a major component of a universal vaccine against meningococcus B. In this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b8b5127afd7034f779fecebe2294f2
https://doi.org/10.1016/j.jmb.2008.12.005
https://doi.org/10.1016/j.jmb.2008.12.005
Autor:
Davide Serruto, Brunella Brunelli, Rino Rappuoli, Laura Santini, Elena Cartocci, Dan M. Granoff, Federica Di Marcello, Mario Contorni, Alessia Biolchi, Beatrice Aricò, Jeannette Adu-Bobie, Jo Anne Welsch, Donatella Mannucci, Daniele Veggi, Francesca Titta, Alessandro Bartalesi, Vanda Cinotti, Mariagrazia Pizza, Stefania Bambini, Barbara Capecchi, Maurizio Morandi, Vega Masignani, Elisa Ovidi, Laura Ciucchi, Francesca Ferlicca, Barbara Galli, Marzia Monica Giuliani, Enrico Luzzi, Silvana Savino, Maurizio Comanducci
Publikováno v:
Proceedings of the National Academy of Sciences. 103:10834-10839
Meningitis and sepsis caused by serogroup B meningococcus are two severe diseases that still cause significant mortality. To date there is no universal vaccine that prevents these diseases. In this work, five antigens discovered by reverse vaccinolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4241595c8145c57824a9c9377a83a3
https://doi.org/10.1073/pnas.0603940103
https://doi.org/10.1073/pnas.0603940103
Autor:
Rino Rappuoli, Laura Santini, Federica Di Marcello, Maria Scarselli, Luisa Lozzi, Silvana Savino, Beatrice Aricò, Marzia Monica Giuliani, Vega Masignani, Mariagrazia Pizza, Brunella Brunelli, Elena Cartocci, Maurizio Comanducci, Alessia Biolchi
Publikováno v:
Infection and Immunity. 73:1151-1160
GNA 1870 is a novel surface-exposed lipoprotein, identified by genome analysis ofNeisseria meningitidisstrain MC58, which induces bactericidal antibodies. Three sequence variants of the protein were shown to be sufficient to induce bactericidal antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921cfbbe39cf2118f079a2d2e0f13564
https://doi.org/10.1128/iai.73.2.1151-1160.2005
https://doi.org/10.1128/iai.73.2.1151-1160.2005
Autor:
Rino Rappuoli, Beatrice Aricò, Mariagrazia Pizza, Barbara Capecchi, Annarita Taddei, Laura Ciucchi, Vega Masignani, Jeannette Adu-Bobie, Federica Di Marcello
Publikováno v:
Molecular Microbiology. 55:687-698
Neisseria meningitidis is a human pathogen, which is a major cause of sepsis and meningitis. The bacterium colonizes the upper respiratory tract of approximately 10% of humans where it lives as a commensal. On rare occasions, it crosses the epitheliu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e89b831f6d2e3412fbf2e8c48d6a2af
https://doi.org/10.1111/j.1365-2958.2004.04423.x
https://doi.org/10.1111/j.1365-2958.2004.04423.x
Autor:
Maurizio Comanducci, Federica Di Marcello, Vega Masignani, Marzia Monica Giuliani, Enrico Balducci, Beatrice Aricò, Mariagrazia Pizza, Maria Scarselli, Davide Serruto, Rino Rappuoli, Stefania Bambini, Daniele Veggi, Silvana Savino, Jeannette Adu-Bobie
Publikováno v:
Molecular Microbiology. 50:1055-1067
Mono ADP-ribosyltransferases (ADPRTs) are a class of functionally conserved enzymes present in prokaryotic and eukaryotic organisms. In bacteria, these enzymes often act as potent toxins and play an important role in pathogenesis. Here we report a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5e9735d41ad22fb4f373656325a2c6
https://doi.org/10.1046/j.1365-2958.2003.03770.x
https://doi.org/10.1046/j.1365-2958.2003.03770.x
Autor:
Barbara Brogioni, Marzia Monica Giuliani, Daniele Veggi, Maurizio Comanducci, Beatrice Aricò, Michele Pallaoro, Enrico Malito, Paola Lo Surdo, Silvana Savino, Annalisa Colaprico, Maria Scarselli, Patrizia Giannetti, Lucia Banci, Francesco Doro, Francesca Cantini, Marta Tontini, Brunella Brunelli, Mariagrazia Pizza, Elena Cartocci, Markus Hilleringmann, Rino Rappuoli, Sara Dragonetti, Matthew J. Bottomley, Federica Di Marcello, Laura Ciucchi, Vincenzo Nardi-Dei, Emmanuelle Palumbo
Publikováno v:
Science translational medicine. 3(91)
The sequence variability of protective antigens is a major challenge to the development of vaccines. For Neisseria meningitidis, the bacterial pathogen that causes meningitis, the amino acid sequence of the protective antigen factor H binding protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda29490a73d0de63e55fdfecad81339
https://pubmed.ncbi.nlm.nih.gov/21878977
https://pubmed.ncbi.nlm.nih.gov/21878977
Autor:
Gabriella Jacomelli, Federica Di Marcello, Laura Notarantonio, Silvia Sestini, Barbara Cerboni, Matteo Bertelli, Giuseppe Pompucci, Hyder Jinnah
Publikováno v:
Metabolic Brain Disease; Jun2009, Vol. 24 Issue 2, p311-319, 9p