Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Federica Del Monte"'
Autor:
Brett C Baggett, Kevin R Murphy, Elif Sengun, Eric Mi, Yueming Cao, Nilufer N Turan, Yichun Lu, Lorraine Schofield, Tae Yun Kim, Anatoli Y Kabakov, Peter Bronk, Zhilin Qu, Patrizia Camelliti, Patrycja Dubielecka, Dmitry Terentyev, Federica del Monte, Bum-Rak Choi, John Sedivy, Gideon Koren
Publikováno v:
eLife, Vol 12 (2023)
Progressive tissue remodeling after myocardial infarction (MI) promotes cardiac arrhythmias. This process is well studied in young animals, but little is known about pro-arrhythmic changes in aged animals. Senescent cells accumulate with age and acce
Externí odkaz:
https://doaj.org/article/d202d60827684d86801b098db8759f70
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Purpose of Review: This review summarizes the current evidence for the involvement of proteotoxicity and protein quality control systems defects in diseases of the central nervous and cardiovascular systems. Specifically, it presents the commonalitie
Externí odkaz:
https://doaj.org/article/03e5714c1e6042069ba48198fb1530ea
Autor:
Marcello Pignataro, Giulia Di Rocco, Lidia Lancellotti, Fabrizio Bernini, Khaushik Subramanian, Elena Castellini, Carlo Augusto Bortolotti, Daniele Malferrari, Daniele Moro, Giovanni Valdrè, Marco Borsari, Federica del Monte
Publikováno v:
Data in Brief, Vol 33, Iss , Pp 106345- (2020)
The reported data are related to a research paper entitled ''Phosphorylated cofilin-2 is more prone to oxidative modifications on Cys39 and favors amyloid fibril formation'' [1]. Info about the formation and redox properties of the disulfide bridge o
Externí odkaz:
https://doaj.org/article/c108370925414735a30303891dd50bbd
Autor:
Marcello Pignataro, Giulia Di Rocco, Lidia Lancellotti, Fabrizio Bernini, Khaushik Subramanian, Elena Castellini, Carlo Augusto Bortolotti, Daniele Malferrari, Daniele Moro, Giovanni Valdrè, Marco Borsari, Federica del Monte
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101691- (2020)
Cofilins are small protein of the actin depolymerizing family. Actin polymerization/depolymerization is central to a number of critical cellular physiological tasks making cofilin a key protein for several physiological functions of the cell. Cofilin
Externí odkaz:
https://doaj.org/article/bc62d1421f1842a4ae2aa047a74fdf92
Autor:
Kishore Kumar S Narasimhan, Asokan Devarajan, Goutam Karan, Sandhya Sundaram, Qin Wang, Thomas van Groen, Federica del Monte, Namakkal S. Rajasekaran
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101739- (2020)
Redox homeostasis regulates key cellular signaling in both physiology and pathology. While perturbations result in shifting the redox homeostasis towards oxidative stress are well documented, the influence of reductive stress (RS) in neurodegenerativ
Externí odkaz:
https://doaj.org/article/7ce61fb16e71489eb3a30960faee7aa0
Autor:
Marco Luciani, Federica del Monte
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 4, Iss 3, p 12 (2017)
Background: Dilated cardiomyopathy (DCM) is an independent nosographic entity characterized by left ventricular dilatation and contractile dysfunction leading to heart failure (HF). The idiopathic form of DCM (iDCM) occurs in the absence of coronarop
Externí odkaz:
https://doaj.org/article/9e7377be52fd43ce8b833914962788e2
Autor:
Sangita Choudhury, Soochan Bae, Qingen Ke, Ji Yoo Lee, Sylvia S Singh, René St-Arnaud, Federica Del Monte, Peter M Kang
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108382 (2014)
Altered vitamin D signaling is associated with cardiac dysfunction, but the pathogenic mechanism is not clearly understood. We examine the mechanism and the role of vitamin D signaling in the development of cardiac dysfunction.We analyzed 1α-hydroxy
Externí odkaz:
https://doaj.org/article/e90a0937a07c4b739d5262cd118d98df
Autor:
Wolfgang Boecker, Oliver Y. Bernecker, Joseph C. Wu, Xinsheng Zhu, Tomohiro Sawa, Luanda Grazette, Anthony Rosenzweig, Federica del Monte, Ulrich Schmidt, Roger J. Hajjar
Publikováno v:
Molecular Imaging, Vol 3 (2004)
Background: Adenoviral gene transfer has been shown to be effective in cardiac myocytes in vitro and in vivo. A major limitation of myocardial gene therapy is the extracardiac transgene expression. Methods: To minimize extracardiac gene expression, w
Externí odkaz:
https://doaj.org/article/8bb6a274c6324e4e9b8bd5f3f56ae6c5
Publikováno v:
Molecular Imaging, Vol 1 (2002)
Cardiac revascularization is presently performed without realtime visual assessment of myocardial blood flow or perfusion. Moreover, gene therapy of the heart cannot, at present, be directed to specific territories at risk for myocardial infarction.
Externí odkaz:
https://doaj.org/article/943f6753cc2d47a486491ce04ab661c8
Autor:
Marco Luciani, Mauro Montalbano, Luca Troncone, Camilla Bacchin, Keita Uchida, Gianlorenzo Daniele, Bethany Jacobs Wolf, Helen M Butler, Justin Kiel, Stefano Berto, Cortney Gensemer, Kelsey Moore, Jordan Morningstar, Thamonwan Diteepeng, Onder Albayram, José F Abisambra, Russell A Norris, Thomas G Di Salvo, Benjamin Prosser, Rakez Kayed, Federica del Monte
Publikováno v:
European Heart Journal. 44:1560-1570
Background Amyloid plaques and neurofibrillary tangles, the molecular lesions that characterize Alzheimer’s disease (AD) and other forms of dementia, are emerging as determinants of proteinopathies ‘beyond the brain’. This study aims to establi