Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Federica Andreoni"'
Autor:
Laura Marquardt, Federica Andreoni, Mathilde Boumasmoud, Tiziano A. Schweizer, Dorothea M. Heuberger, Elena Parietti, Sanne Hertegonne, Jana Epprecht, Dario Mattle, Anna K. Raez, Ewerton Marques‐Maggio, Reto A. Schuepbach, Barbara Hasse, Srikanth Mairpady‐Shambat, Silvio D. Brugger, Annelies S. Zinkernagel
Publikováno v:
MicrobiologyOpen, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract Group A streptococcal (GAS; aka Streptococcus pyogenes) meningitis is a fulminant disease associated with high morbidity and mortality. To elucidate the mechanisms underlying the invasiveness of GAS in meningitis, we compared GAS isolates de
Externí odkaz:
https://doaj.org/article/f22407c14bca41b089746197c77dec28
Autor:
Vanina Dengler Haunreiter, Andrea Tarnutzer, Julian Bär, Manuela von Matt, Sanne Hertegonne, Federica Andreoni, Clément Vulin, Lisa Künzi, Carmen Menzi, Patrick Kiefer, Philipp Christen, Julia A. Vorholt, Annelies S. Zinkernagel
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Beta-lactam antibiotics are widely used to treat infections caused by the important human pathogen Staphylococcus aureus. Resistance to beta-lactams, as found in methicillin-resistant S. aureus, renders effective treatment difficult. The sec
Externí odkaz:
https://doaj.org/article/5d967d5640f44fa9b032413583e13a24
Autor:
Anna K. Räz, Federica Andreoni, Mathilde Boumasmoud, Judith Bergada-Pijuan, Tiziano A. Schweizer, Srikanth Mairpady Shambat, Barbara Hasse, Annelies S. Zinkernagel, Silvio D. Brugger
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Staphylococcus aureus carriage is a risk factor for invasive infections. Unique genetic elements favoring the transition from colonizing to invasive phenotype have not yet been identified, and phenotypic adaptation traits are understudied. W
Externí odkaz:
https://doaj.org/article/75d2ceecac8d4109af782784959115fc
Autor:
René Bergmann, Giuseppe Gulotta, Federica Andreoni, Tomoko Sumitomo, Shigetada Kawabata, Annelies S. Zinkernagel, Gursharan S. Chhatwal, Victor Nizet, Manfred Rohde, Satoshi Uchiyama
Publikováno v:
Infectious Microbes & Diseases, Vol 4, Iss 3, Pp 116-123 (2022)
Abstract. Autophagy serves an innate immune function in defending the host against invading bacteria, including group A Streptococcus (GAS). Autophagy is regulated by numerous host proteins, including the endogenous negative regulator calpain, a cyto
Externí odkaz:
https://doaj.org/article/1eec279e7b4a400cb54f17b75700c7ee
Autor:
Tiziano A. Schweizer, Federica Andreoni, Claudio Acevedo, Thomas C. Scheier, Irina Heggli, Ewerton Marques Maggio, Nadia Eberhard, Silvio D. Brugger, Stefan Dudli, Annelies S. Zinkernagel
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
To understand the pathophysiology of spondylodiscitis due to Staphylococcus aureus, an emerging infectious disease of the intervertebral disc (IVD) and vertebral body with a high complication rate, we combined clinical insights and experimental appro
Externí odkaz:
https://doaj.org/article/0416ffc9449649a29e014774dafcec60
Autor:
Philipp K. Buehler, Annelies S. Zinkernagel, Daniel A. Hofmaenner, Pedro David Wendel Garcia, Claudio T. Acevedo, Alejandro Gómez-Mejia, Srikanth Mairpady Shambat, Federica Andreoni, Martina A. Maibach, Jan Bartussek, Matthias P. Hilty, Pascal M. Frey, Reto A. Schuepbach, Silvio D. Brugger
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 4, Pp 100229- (2021)
Summary: The impact of secondary bacterial infections (superinfections) in coronavirus disease 2019 (COVID-19) is not well understood. In this prospective, monocentric cohort study, we aim to investigate the impact of superinfections in COVID-19 pati
Externí odkaz:
https://doaj.org/article/db4a2e63c5514299b519150a27bff493
Autor:
Andrina Neff, Lionel Chok, Ulrich von Both, Ulrich Matt, Andrea Tarnutzer, Federica Andreoni, Mark van der Linden, Jan A. Plock, Philipp K. Buehler, Silvio D. Brugger, Reto A. Schuepbach, Reinhard Zbinden, Annelies S. Zinkernagel
Publikováno v:
Swiss Medical Weekly, Vol 150, Iss 4950 (2020)
AIMS OF THE STUDY Invasive streptococcal infections affect more than half a million patients worldwide every year and have a high lethality. Little is known about the epidemiology and microbiological characteristics of streptococcal infections in Sw
Externí odkaz:
https://doaj.org/article/7943d5de2c7c4e7daade92230fe37efb
Autor:
Rocco Piazza, Vera Magistroni, Angela Mogavero, Federica Andreoni, Chiara Ambrogio, Roberto Chiarle, Luca Mologni, Petra S Bachmann, Richard B Lock, Paola Collini, Giuseppe Pelosi, Carlo Gambacorti-Passerini
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 5, Pp 511-522 (2013)
BIM is a proapoptotic member of the Bcl-2 family. Here, we investigated the epigenetic status of the BIM locus in NPM/ALK+ anaplastic large cell lymphoma (ALCL) cell lines and in lymph node biopsies from NPM/ALK+ ALCL patients. We show that BIM is ep
Externí odkaz:
https://doaj.org/article/03b409ae70454479a9d66bf43e7da19e
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81298 (2013)
BACKGROUND: The family of 4 related protease-activated receptors (PAR-1, 2, 3 & 4) expressed by mammalian cells allow to sense for and react to extracellular proteolytic activity. Since major human bacterial pathogens secret a wide array of protease(
Externí odkaz:
https://doaj.org/article/78bc1b68cbbf423dbce26f797600d2eb
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002736 (2012)
Group A Streptococcus (GAS) has developed a broad arsenal of virulence factors that serve to circumvent host defense mechanisms. The virulence factor DNase Sda1 of the hyperinvasive M1T1 GAS clone degrades DNA-based neutrophil extracellular traps all
Externí odkaz:
https://doaj.org/article/433386330b4345869ed94837c67562e9