Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Federica, Villanova"'
Autor:
Panagiotis Karagiannis, Federica Villanova, Debra H Josephs, Isabel Correa, Mieke Van Hemelrijck, Carl Hobbs, Louise Saul, Isioma U Egbuniwe, Isabella Tosi, Kristina M Ilieva, Emma Kent, Eduardo Calonje, Mark Harries, Ian Fentiman, Joyce Taylor-Papadimitriou, Joy Burchell, James F Spicer, Katie E Lacy, Frank O Nestle, Sophia N Karagiannis
Publikováno v:
OncoImmunology, Vol 4, Iss 11 (2015)
Emerging evidence suggests pathological and immunoregulatory functions for IgG4 antibodies and IgG4+ B cells in inflammatory diseases and malignancies. We previously reported that IgG4 antibodies restrict activation of immune effector cell functions
Externí odkaz:
https://doaj.org/article/5cf1db22e937403383ee10994dd14c28
Autor:
Federica Villanova, Paola Di Meglio, Margaret Inokuma, Nima Aghaeepour, Esperanza Perucha, Jennifer Mollon, Laurel Nomura, Maria Hernandez-Fuentes, Andrew Cope, A Toby Prevost, Susanne Heck, Vernon Maino, Graham Lord, Ryan R Brinkman, Frank O Nestle
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e65485 (2013)
Discovery of novel immune biomarkers for monitoring of disease prognosis and response to therapy in immune-mediated inflammatory diseases is an important unmet clinical need. Here, we establish a novel framework for immunological biomarker discovery,
Externí odkaz:
https://doaj.org/article/29156ce7ba8347c983bb5973c1a6494f
Autor:
Emanuele de Rinaldis, Anna Chapman, Paola Di Meglio, Chiew Yee Chiew Yee Loh, Evan W. Newell, K. Grys, Consol Farrera, Hemawtee Sreeneebus, Karen Wei Weng Teng, Susanne Heck, Michael Wong, Catherine H. Smith, Rossella Melchiotti, Isabella Tosi, Jinmiao Chen, Gayathri K. Perera, Filipe Gracio, Nedyalko Petrov, Federica Villanova, Frank O. Nestle, Jonathan Barker
Publikováno v:
Farrera, C, Melchiotti, R, Petrov, N, Wei Weng Teng, K, Wong, M T, Loh, C Y, Villanova, F, Tosi, I, Chen, J, Grys, K, Sreeneebus, H, Chapman, A, Perera, G K, Heck, S, Gracio, F, de Rinaldis, E, Barker, J N, Smith, C H, Nestle, F O, Newell, E W & Di Meglio, P 2020, ' T-cell phenotyping uncovers systemic features of atopic dermatitis and psoriasis ', Journal of Allergy and Clinical Immunology, vol. 145, no. 3, pp. 1021-1025.e15 . https://doi.org/10.1016/j.jaci.2019.11.030
Deep-immunophenotyping of the circulatory T cell compartment using mass cytometry and unsupervised clustering analysis, identifies phenotypic and functional differences in patients with atopic dermatitis (AD) and psoriasis, highlighting the stronger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fc473b3514c1988610ba3c58251bd4
https://kclpure.kcl.ac.uk/en/publications/5c6cb9fb-1789-4f45-a68b-94fd103a8ea8
https://kclpure.kcl.ac.uk/en/publications/5c6cb9fb-1789-4f45-a68b-94fd103a8ea8
Autor:
Paola Di Meglio, Antonella Di Cesare, Ute Laggner, Chung-Ching Chu, Luca Napolitano, Federica Villanova, Isabella Tosi, Francesca Capon, Richard C Trembath, Ketty Peris, Frank O Nestle
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17160 (2011)
IL-23 and Th17 cells are key players in tissue immunosurveillance and are implicated in human immune-mediated diseases. Genome-wide association studies have shown that the IL23R R381Q gene variant protects against psoriasis, Crohn's disease and ankyl
Externí odkaz:
https://doaj.org/article/65d3ec30fdb44d5cb1064f1049b3c293
Autor:
Fabrizio Vianello, Federica Villanova, Veronica Tisato, Stefania Lymperi, Ka-Kei Ho, Ana R. Gomes, David Marin, Dominique Bonnet, Jane Apperley, Eric W.-F. Lam, Francesco Dazzi
Publikováno v:
Haematologica, Vol 95, Iss 7 (2010)
Background Residual chronic myeloid leukemia disease following imatinib treatment has been attributed to the presence of quiescent leukemic stem cells intrinsically resistant to imatinib. Mesenchymal stromal cells in the bone marrow may favor the per
Externí odkaz:
https://doaj.org/article/35ae18b3eceb4d728e11af699a44f10c
Autor:
Nick D.L. Owens, Brigitta Stockinger, Helena Ahlfors, Federica Villanova, Isabella Tosi, Keiji Hirota, Paola Di Meglio, João H. Duarte, Ulrich Mrowietz, Michael J. Gilchrist, Ying Li, Frank O. Nestle
Publikováno v:
Di Meglio, P, Duarte, J H, Ahlfors, H, Owens, N D L, Li, Y, Villanova, F, Tosi, I, Hirota, K, Nestle, F O, Mrowietz, U, Gilchrist, M J & Stockinger, B 2014, ' Activation of the aryl hydrocarbon receptor dampens the severity of inflammatory skin conditions ', Immunity, vol. 40, no. 6, pp. 989-1001 . https://doi.org/10.1016/j.immuni.2014.04.019
Immunity
Immunity
Summary Environmental stimuli are known to contribute to psoriasis pathogenesis and that of other autoimmune diseases, but the mechanisms are largely unknown. Here we show that the aryl hydrocarbon receptor (AhR), a transcription factor that senses e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ec6f8984938841b3976156b6f2dec3
Autor:
Louise Saul, Kristina M. Ilieva, Heather J. Bax, Panagiotis Karagiannis, Isabel Correa, Irene Rodriguez-Hernandez, Debra H. Josephs, Isabella Tosi, Isioma U. Egbuniwe, Sara Lombardi, Silvia Crescioli, Carl Hobbs, Federica Villanova, Anthony Cheung, Jenny L. C. Geh, Ciaran Healy, Mark Harries, Victoria Sanz-Moreno, David J. Fear, James F. Spicer, Katie E. Lacy, Frank O. Nestle, Sophia N. Karagiannis
Publikováno v:
Saul, L, Ilieva, K M, Bax, H J, Karagiannis, P, Correa, I, Rodriguez-Hernandez, I, Josephs, D H, Tosi, I, Egbuniwe, I U, Lombardi, S, Crescioli, S, Hobbs, C, Villanova, F, Cheung, A, Geh, J L C, Healy, C, Harries, M, Sanz-Moreno, V, Fear, D J, Spicer, J F, Lacy, K E, Nestle, F O & Karagiannis, S N 2016, ' IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin ', Scientific Reports, vol. 6, 29736 . https://doi.org/10.1038/srep29736
Scientific Reports
Scientific Reports
B cells participate in immune surveillance in human circulation and tissues, including tumors such as melanoma. By contrast, the role of humoral responses in cutaneous immunity is underappreciated. We report circulating skin-homing CD22+CLA+B cells i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4e5f6974dba43b7bcd23d159cf9ff10c
https://kclpure.kcl.ac.uk/ws/files/54701902/srep29736.pdf
https://kclpure.kcl.ac.uk/ws/files/54701902/srep29736.pdf
Autor:
Alessio Mylonas, Federica Villanova, Frank O. Nestle, Isabella Tosi, Curdin Conrad, Alexander A. Navarini, Paola Di Meglio
Publikováno v:
The Journal of allergy and clinical immunology, vol. 138, no. 1, pp. 274-276.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f944293525776cf93f45ecdbc7c4e8
https://serval.unil.ch/notice/serval:BIB_14A789D6773B
https://serval.unil.ch/notice/serval:BIB_14A789D6773B
Autor:
F. Pietrogrande, Fabrizio Vianello, Anna Furlan, Federica Villanova, Mariella Sanzari, Marilena Celadin
Publikováno v:
Leukemia & Lymphoma. 51:107-113
Rituximab maintenance therapy provides a significant benefit in patients with indolent B-cell non-Hodgkin lymphoma (NHL). Based on its efficacy in improving response to chemotherapy, the anti-CD20 antibody is currently under evaluation as maintenance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7d3a5af35e3892c1d9e87a6339d7bc
https://doi.org/10.3109/10428190903349688
https://doi.org/10.3109/10428190903349688
Publikováno v:
Personalized Treatment Options in Dermatology ISBN: 9783662458396
Four decades of clinical, translational, and basic psoriasis research have greatly advanced our understanding of psoriasis pathogenesis. Psoriasis is a complex disease resulting from the interaction of genetic, environmental, and immunological factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae3a93be7fe238741b77d8aba65fcad8
https://doi.org/10.1007/978-3-662-45840-2_6
https://doi.org/10.1007/978-3-662-45840-2_6