Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Federica, Montanaro"'
Autor:
Elisa Gouvêa Bogossian, Chahnez Taleb, Raffaele Aspide, Rafael Badenes, Denise Battaglini, Federico Bilotta, Aaron Blandino Ortiz, Anselmo Caricato, Carlo Alberto Castioni, Giuseppe Citerio, Gioconda Ferraro, Costanza Martino, Isabella Melchionda, Federica Montanaro, Berta Monleon Lopez, Consolato Gianluca Nato, Michael Piagnerelli, Edoardo Picetti, Chiara Robba, Olivier Simonet, Aurelie Thooft, Fabio Silvio Taccone
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-11 (2023)
Abstract Introduction Altered levels of cerebrospinal fluid (CSF) glucose and lactate concentrations are associated with poor outcomes in acute brain injury patients. However, no data on changes in such metabolites consequently to therapeutic interve
Externí odkaz:
https://doaj.org/article/c2ed81f5c0274e3283204443d4d5c798
Autor:
Gaetano Scaramuzzo, Francesco Nucera, Alessio Asmundo, Roberto Messina, Matilde Mari, Federica Montanaro, Matt D. Johansen, Francesco Monaco, Guido Fadda, Giovanni Tuccari, Nicole G. Hansbro, Philip M. Hansbro, Trevor T. Hansel, Ian M. Adcock, Antonio David, Paul Kirkham, Gaetano Caramori, Carlo Alberto Volta, Savino Spadaro
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-24 (2023)
Abstract The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection can be asymptomatic or cause a disease (COVID-19) characterized by different levels of severity. The main cause of severe COVID-19 and death is represented by acute (
Externí odkaz:
https://doaj.org/article/09db15bec1ab49ba975346d548e55894
Autor:
Mathilde Doisy, Ophélie Vacca, Claire Fergus, Talia Gileadi, Minou Verhaeg, Amel Saoudi, Thomas Tensorer, Luis Garcia, Vincent P. Kelly, Federica Montanaro, Jennifer E. Morgan, Maaike van Putten, Annemieke Aartsma-Rus, Cyrille Vaillend, Francesco Muntoni, Aurélie Goyenvalle
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3243 (2023)
Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene that disrupt the open reading frame and thus prevent production of functional dystrophin proteins. Recent advances in DMD treatment, notably exon skipping and AAV gene therapy,
Externí odkaz:
https://doaj.org/article/29a1434a711345e993444660698a38fe
Autor:
Amel Saoudi, Claire Fergus, Talia Gileadi, Federica Montanaro, Jennifer E. Morgan, Vincent P. Kelly, Thomas Tensorer, Luis Garcia, Cyrille Vaillend, Francesco Muntoni, Aurélie Goyenvalle
Publikováno v:
Cells, Vol 12, Iss 6, p 908 (2023)
Nucleic acid-based therapies have demonstrated great potential for the treatment of monogenetic diseases, including neurologic disorders. To date, regulatory approval has been received for a dozen antisense oligonucleotides (ASOs); however, these che
Externí odkaz:
https://doaj.org/article/beb2afcd99a94239af7d9e7e2d20f5e8
Autor:
Gaetano Scaramuzzo, Savino Spadaro, Elena Spinelli, Andreas D. Waldmann, Stephan H. Bohm, Irene Ottaviani, Federica Montanaro, Lorenzo Gamberini, Elisabetta Marangoni, Tommaso Mauri, Carlo Alberto Volta
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Transpulmonary driving pressure (DPL) corresponds to the cyclical stress imposed on the lung parenchyma during tidal breathing and, therefore, can be used to assess the risk of ventilator-induced lung injury (VILI). Its measurement at the bedside req
Externí odkaz:
https://doaj.org/article/4b0bf3b5bc9a4b338ea7fdc7c080c4fe
Autor:
Gaetano Scaramuzzo, Dan Stieper Karbing, Alberto Fogagnolo, Tommaso Mauri, Elena Spinelli, Matilde Mari, Cecilia Turrini, Federica Montanaro, Carlo Alberto Volta, Stephen Edward Rees, Savino Spadaro
Publikováno v:
Respiratory Care. 68:188-198
Autor:
Saleh Omairi, Kwan-Leong Hau, Henry Collin-Hooper, Federica Montanaro, Aurelie Goyenvalle, Luis Garcia, Ketan Patel
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 409-418 (2017)
Exon skipping mediated by tricyclo-DNA (tc-DNA) antisense oligonucleotides has been shown to induce significant levels of dystrophin restoration in mdx, a mouse model of Duchenne muscular dystrophy. This translates into significant improvement in key
Externí odkaz:
https://doaj.org/article/d1b8a4b5cb11485c8560797a0dfebc28
Autor:
Audrey Bourdon, Virginie François, Liwen Zhang, Aude Lafoux, Bodvael Fraysse, Gilles Toumaniantz, Thibaut Larcher, Tiphaine Girard, Mireille Ledevin, Cyrielle Lebreton, Agnès Hivonnait, Anna Creismeas, Marine Allais, Basile Marie, Justine Guguin, Véronique Blouin, Séverine Remy, Ignacio Anegon, Corinne Huchet, Alberto Malerba, Betty Kao, Anita Le Heron, Philippe Moullier, George Dickson, Linda Popplewell, Oumeya Adjali, Federica Montanaro, Caroline Le Guiner
Publikováno v:
Gene Therapy. 29:520-535
Autor:
Gaetano, Scaramuzzo, Dan Stieper, Karbing, Alberto, Fogagnolo, Tommaso, Mauri, Elena, Spinelli, Matilde, Mari, Cecilia, Turrini, Federica, Montanaro, Carlo Alberto, Volta, Stephen Edward, Rees, Savino, Spadaro
Publikováno v:
Respiratory care.
COVID-19-related ARDS is characterized by severe hypoxemia with initially preserved lung compliance and impaired ventilation/perfusion (V̇/Q̇) matching. PEEP can increase end-expiratory lung volume, but its effect on V̇/Q̇ mismatch in COVID-19-re
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0177788 (2017)
Commonly used methods for site-directed DNA mutagenesis require copying the entire target plasmid. These methods allow relatively easy modification of DNA sequences in small plasmids but become less efficient and faithful for large plasmids, necessit
Externí odkaz:
https://doaj.org/article/63755e15afe34031a20ae90ade04c679