Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Federica, Mirimao"'
Autor:
Laura Mannarino, Federica Mirimao, Nicolò Panini, Lara Paracchini, Sergio Marchini, Luca Beltrame, Rosy Amodeo, Federica Grosso, Roberta Libener, Irene De Simone, Giovanni L. Ceresoli, Paolo A. Zucali, Monica Lupi, Maurizio D’Incalci
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-9 (2022)
Abstract Although clinical antitumor activity of Tumor Treating Fields (TTFields) has been reported in malignant pleural mesothelioma (MPM) patients, the mechanisms behind the different selectivity displayed by the various MPM histotypes to this phys
Externí odkaz:
https://doaj.org/article/5bde7304069647c4a6e5b02fd41387ae
Publikováno v:
Genes
Genes, Vol 11, Iss 3, p 326 (2020)
Volume 11
Issue 3
Genes, Vol 11, Iss 3, p 326 (2020)
Volume 11
Issue 3
Common fragile sites (CFSs) are particularly vulnerable regions of the genome that become visible as breaks, gaps, or constrictions on metaphase chromosomes when cells are under replicative stress. Impairment in DNA replication, late replication timi
Autor:
Giovanni Luca Ceresoli, Maurizio D'Incalci, Federica Mirimao, Antonio Maconi, Federica Grosso, Lara Paracchini, Monica Lupi, Laura Mannarino, Sergio Marchini, Serena Penpa, Greta Piazza, Nicolò Panini
Publikováno v:
Cancer Research. 81:1064-1064
Despite the increasing knowledge of the biology of malignant pleural mesothelioma (MPM), patients with this diagnosis still have a poor prognosis with a 5-year survival rate of lower than 10%. The effectiveness demonstrated by Tumor Treating Fields (
Autor:
Nicolò Panini, Sergio Marchini, Giulia Protti, Maurizio D'Incalci, Roberta Frapolli, Monica Lupi, Laura Mannarino, Ilaria Craparotta, Federica Mirimao
Publikováno v:
Molecular Cancer Therapeutics. 18:LB-B13
The reported clinical activity of lurbinectedin in Small Cell Lung Cancer (SCLC) prompted us to investigate the selective mechanism of this drug in SCLC cell lines. Since lurbinectedin binds the DNA minor groove modifying DNA structure, we hypothesiz