Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Federica, Marasca"'
Autor:
Camilla Fontana, Federica Marasca, Livia Provitera, Sara Mancinelli, Nicola Pesenti, Shruti Sinha, Sofia Passera, Sergio Abrignani, Fabio Mosca, Simona Lodato, Beatrice Bodega, Monica Fumagalli
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background Preterm birth affects almost 9–11% of newborns and is one of the leading causes of childhood neurodevelopmental disabilities; the underlying molecular networks are poorly defined. In neurons, retrotransposons LINE-1 (L1) are an
Externí odkaz:
https://doaj.org/article/eb9f42366ba641508cb079d17db5b002
Autor:
Mara Mazzola, Gianluca Deflorian, Alex Pezzotta, Laura Ferrari, Grazia Fazio, Erica Bresciani, Claudia Saitta, Luca Ferrari, Monica Fumagalli, Matteo Parma, Federica Marasca, Beatrice Bodega, Paola Riva, Franco Cotelli, Andrea Biondi, Anna Marozzi, Gianni Cazzaniga, Anna Pistocchi
Publikováno v:
Haematologica, Vol 104, Iss 7 (2019)
The nucleophosmin 1 gene (NPM1) is the most frequently mutated gene in acute myeloid leukemia. Notably, NPM1 mutations are always accompanied by additional mutations such as those in cohesin genes RAD21, SMC1A, SMC3, and STAG2 but not in the cohesin
Externí odkaz:
https://doaj.org/article/2a860a51750740278fb6788ba7cc49e3
Autor:
Federica Marasca, Shruti Sinha, Rebecca Vadalà, Benedetto Polimeni, Valeria Ranzani, Elvezia Maria Paraboschi, Filippo Vittorio Burattin, Marco Ghilotti, Mariacristina Crosti, Maria Luce Negri, Susanna Campagnoli, Samuele Notarbartolo, Andrea Sartore-Bianchi, Salvatore Siena, Daniele Prati, Giovanni Montini, Giuseppe Viale, Olga Torre, Sergio Harari, Renata Grifantini, Giulia Soldà, Stefano Biffo, Sergio Abrignani, Beatrice Bodega
Publikováno v:
Nature Genetics. 54:180-193
How gene expression is controlled to preserve human T cell quiescence is poorly understood. Here we show that non-canonical splicing variants containing long interspersed nuclear element 1 (LINE1) enforce naive CD4+ T cell quiescence. LINE1-containin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2a7c24f26193a0defb799f947cb6fc
https://doi.org/10.1038/s41588-021-00989-7
https://doi.org/10.1038/s41588-021-00989-7
Autor:
Erica Gasparotto, Filippo Vittorio Burattin, Valeria Di Gioia, Michele Panepuccia, Valeria Ranzani, Federica Marasca, Beatrice Bodega
Publikováno v:
International Journal of Molecular Sciences. 24:2610
The genome is no longer deemed as a fixed and inert item but rather as a moldable matter that is continuously evolving and adapting. Within this frame, Transposable Elements (TEs), ubiquitous, mobile, repetitive elements, are considered an alive port
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36c4ae819fb88d79047f07ff4d557aef
https://doi.org/10.3390/ijms24032610
https://doi.org/10.3390/ijms24032610
Autor:
Beatrice Bodega, Francesco Gregoretti, Chiara Chiereghin, Eleonora Sala, Alice Cortesi, Shruti Sinha, Louis Antonelli, Matthieu Pesant, Gennaro Oliva, Federica Marasca, Giulia Soldà
Publikováno v:
Genome research 29 (2019): 883–895. doi:10.1101/gr.233288.117
info:cnr-pdr/source/autori:Cortesi, Alice; Pesant, Matthieu; Sinha, Shruti; Marasca, Federica; Sala, Eleonora; Gregoretti, Francesco; Antonelli, Laura; Oliva, Gennaro; Chiereghin, Chiara; Solda, Giulia; Bodega, Beatrice/titolo:4q-D4Z4 chromatin architecture regulates the transcription of muscle atrophic genes in facioscapulohumeral muscular dystrophy/doi:10.1101%2Fgr.233288.117/rivista:Genome research/anno:2019/pagina_da:883/pagina_a:895/intervallo_pagine:883–895/volume:29
info:cnr-pdr/source/autori:Cortesi, Alice; Pesant, Matthieu; Sinha, Shruti; Marasca, Federica; Sala, Eleonora; Gregoretti, Francesco; Antonelli, Laura; Oliva, Gennaro; Chiereghin, Chiara; Solda, Giulia; Bodega, Beatrice/titolo:4q-D4Z4 chromatin architecture regulates the transcription of muscle atrophic genes in facioscapulohumeral muscular dystrophy/doi:10.1101%2Fgr.233288.117/rivista:Genome research/anno:2019/pagina_da:883/pagina_a:895/intervallo_pagine:883–895/volume:29
Despite increasing insights in genome structure organization, the role of DNA repetitive elements, accounting for more than two thirds of the human genome, remains elusive. Facioscapulohumeral muscular dystrophy (FSHD) is associated with deletion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945624de9ddd0e004543fcd4239bf223
https://doi.org/10.1101/gr.233288.117
https://doi.org/10.1101/gr.233288.117
Autor:
Clara De Palma, Anna Pistocchi, Marina Mora, Federica Marasca, Anna Marozzi, Cecilia Gelfi, Daniele Capitanio, Cinzia Bragato, Marco Cafora, Beatrice Bodega, Marco Spreafico
Duchenne muscular dystrophy (DMD) causes progressive skeletal muscle degeneration and currently there are few therapeutic options. The identification of new drug targets and their validation in model systems of DMD could be a promising approach to ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874ce550f787d5f655e96ba5e1560502
https://hdl.handle.net/10281/400997
https://hdl.handle.net/10281/400997
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2157
Epigenetic mechanisms govern the quality, the stability, and the responsiveness of transcriptional programs to the environment. This regulation is ensured via the concerted action of different players (transcription factors, "reader" and "writer" enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9fd621b1a7c2cbd9de9817e517eec599
https://pubmed.ncbi.nlm.nih.gov/32820410
https://pubmed.ncbi.nlm.nih.gov/32820410
Publikováno v:
Methods in Molecular Biology ISBN: 9781071606636
Epigenetic mechanisms govern the quality, the stability, and the responsiveness of transcriptional programs to the environment. This regulation is ensured via the concerted action of different players (transcription factors, "reader" and "writer" enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::309036372a91d54919021216c6d2c1d8
https://doi.org/10.1007/978-1-0716-0664-3_16
https://doi.org/10.1007/978-1-0716-0664-3_16
Autor:
Beatrice Bodega, Valeria Ranzani, Benedetto Polimeni, Rebecca Vadalà, Federica Marasca, Erica Gasparotto
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3201, p 3201 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Transposable elements (TEs), which cover ~45% of the human genome, although firstly considered as “selfish” DNA, are nowadays recognized as driving forces in eukaryotic genome evolution. This capability resides in generating a plethora of sophist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3604a74577f5c6e4354091cc1ecdfb40
https://www.mdpi.com/1422-0067/21/9/3201
https://www.mdpi.com/1422-0067/21/9/3201
Publikováno v:
Journal of Visualized Experiments.
A major question in cell biology is genomic organization within the nuclear space and how chromatin architecture can influence processes such as gene expression, cell identity and differentiation. Many approaches developed to study the 3D architectur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f631c53c52deed604cc7621ccc0fdd4
https://doi.org/10.3791/60712
https://doi.org/10.3791/60712