Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Federica, Lopes"'
Autor:
Willem Ombelet, Federica Lopes
Publikováno v:
Reproduction and Fertility, Vol 5, Iss 3, Pp 1-5 (2024)
Infertility affects millions worldwide, with significant medical, financial, and emotional challenges, particularly in low- and middle-income countries (LMICs). Cultural, religious, financial, and gender-related barriers hinder access to treatment, e
Externí odkaz:
https://doaj.org/article/5de31c98f0274c1a8ec99872a2f61cd1
Autor:
Federica Lopes, Prathima Tholeti, Satish K. Adiga, Richard A. Anderson, Rod T. Mitchell, Norah Spears
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 114-123 (2021)
Chemotherapy can affect testis development of young boys with cancer, reducing the chances of fatherhood in adulthood. Studies using experimental models are needed to determine the damage caused by individual chemotherapy drugs in order to predict th
Externí odkaz:
https://doaj.org/article/d370702363bb46eb9fd9cf95d0b4cafd
Autor:
Melissa D. Tharmalingam, Gabriele Matilionyte, William H. B. Wallace, Jan-Bernd Stukenborg, Kirsi Jahnukainen, Elizabeth Oliver, Anne Goriely, Sheila Lane, Jingtao Guo, Bradley Cairns, Anne Jorgensen, Caroline M. Allen, Federica Lopes, Richard A. Anderson, Norah Spears, Rod T. Mitchell
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Clinical studies indicate chemotherapy agents used in childhood cancer treatment regimens may impact future fertility. However, effects of individual agents on prepubertal human testis, necessary to identify later risk, have not b
Externí odkaz:
https://doaj.org/article/3ef3b5fe34214194b1c988c0460708f2
Autor:
Gabriele Matilionyte, Melissa D. Tharmalingam, Iris Sanou, Federica Lopes, Sheila Lane, Jan-Bernd Stukenborg, Norah Spears, Richard A. Anderson, Rod T. Mitchell
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Background: Retrospective studies in adult survivors of childhood cancer show long-term impacts of exposure to alkylating chemotherapy on future fertility. We recently demonstrated germ cell loss in immature human testicular tissues following exposur
Externí odkaz:
https://doaj.org/article/73e992f0088d4b99bda41cd39c0ac9e2
Publikováno v:
Reproduction and Fertility, Vol 2, Iss 4, Pp L7-L9 (2021)
Boys administered chemotherapy to treat cancer are at risk of damage to their healthy testicular tissue, which can lead to infertility in adulthood. Researchers are therefore investigating treatments to protect the testis during cancer treatment. Her
Externí odkaz:
https://doaj.org/article/0d84184313404350b8058ea76f0ac07a
Autor:
Pietro Badagliacca, Fabrizio Agnoletti, Ilenia Drigo, Valentina Merildi, Federica Lopes, Cinzia Pompilii, Iolanda Mangone, Massimo Scacchia, Alfreda Tonelli, Luke Masson
Publikováno v:
Veterinaria Italiana, Vol 54, Iss 3 (2019)
The virulence gene profile of 26 rabbit enteropathogenic Escherichia coli strains, isolated from 17 colibacillosis outbreaks located in two regions of Northern Italy, was determined using an Echerichia coli virulence DNA microarray. All strains were
Externí odkaz:
https://doaj.org/article/4e544efb7c2e4cdd9eadff32c0249775
Publikováno v:
Journal of Medical Microbiology and Infectious Diseases, Vol 3, Iss 1, Pp 29-34 (2015)
Introduction: In Iran, invasive nontyphoidal Salmonella (iNTS) disease causes severe bacteremic illness among children
Externí odkaz:
https://doaj.org/article/06039b5d348148b284a8ca2e8d641f1c
Publikováno v:
Reproduction and Fertility, Vol 2, Iss 4, Pp L7-L9 (2021)
Reproduction & Fertility
Reproduction & Fertility
Lay summary Boys administered chemotherapy to treat cancer are at risk of damage to their healthy testicular tissue, which can lead to infertility in adulthood. Researchers are therefore investigating treatments to protect the testis during cancer tr
Autor:
Stephanie Morgan, Lucy Nevin, Richard A. Anderson, Rebecca Matthews, Norah Spears, Jin Liu, Federica Lopes
Publikováno v:
Reproduction (Cambridge, England)
Lopes, F, Lui, J, Morgan, S, Matthews, R, Nevin, L, Anderson, R & Spears, N 2020, ' Single and combined effects of cisplatin and doxorubicin on the human and mouse ovary in vitro ', Reproduction, vol. 159, no. 2, pp. 193–204 . https://doi.org/10.1530/REP-19-0279
Lopes, F, Lui, J, Morgan, S, Matthews, R, Nevin, L, Anderson, R & Spears, N 2020, ' Single and combined effects of cisplatin and doxorubicin on the human and mouse ovary in vitro ', Reproduction, vol. 159, no. 2, pp. 193–204 . https://doi.org/10.1530/REP-19-0279
Chemotherapy drugs are administered to patients using combination regimens, and as such the possibility of multiplicative effects between drugs need to be investigated. This study examines the individual and combined effects of the chemotherapy drugs
Publikováno v:
Molecular Human Reproduction
Allen, C, Lopes, F, Mitchell, R & Spears, N 2020, ' Comparative gonadotoxicity of the chemotherapy drugs cisplatin and carboplatin on prepubertal mouse gonads ', Molecular Human Reproduction . https://doi.org/10.1093/molehr/gaaa008
Allen, C, Lopes, F, Mitchell, R & Spears, N 2020, ' Comparative gonadotoxicity of the chemotherapy drugs cisplatin and carboplatin on prepubertal mouse gonads ', Molecular Human Reproduction . https://doi.org/10.1093/molehr/gaaa008
The treatment of childhood cancer with chemotherapy drugs can result in infertility in adulthood. Newer generations of drugs are developed to replace parent drugs, with the potential benefits of less toxic side effects. For platinum alkylating-like d