Výsledky vyhledávání - "Federica, La Russa"

Akademický článek

Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration.

Autor: Sheona Watson-Scales, Bernadett Kalmar, Eva Lana-Elola, Dorota Gibbins, Federica La Russa, Frances Wiseman, Matthew Williamson, Rachele Saccon, Amy Slender, Anna Olerinyova, Radma Mahmood, Emma Nye, Heather Cater, Sara Wells, Y Eugene Yu, David L H Bennett, Linda Greensmith, Elizabeth M C Fisher, Victor L J Tybulewicz

Publikováno v: PLoS Genetics, Vol 14, Iss 5, p e1007383 (2018)

Down Syndrome (DS) is caused by trisomy of chromosome 21 (Hsa21) and results in a spectrum of phenotypes including learning and memory deficits, and motor dysfunction. It has been hypothesized that an additional copy of a few Hsa21 dosage-sensitive g

Externí odkaz: https://doaj.org/article/cf34bed66d614aab8625e9cbd15f2434

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Sensory modulation of airways immunity

Autor: Tibor Z. Veres, Susann Dehmel, Armin Braun, Federica La Russa

Publikováno v: Neuroscience Letters. 760:136042

The airways are constantly exposed to a multitude of inhaled particles and, as such, require a finely tuned discrimination between harmful or potentially threatening stimuli, and discrete responses to maintain homeostasis. Both the immune and nervous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebfc66bec6d0c363a1a2d74477a82de
https://doi.org/10.1016/j.neulet.2021.136042

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A transcriptional toolbox for exploring peripheral neuro-immune interactions

Autor: Monica Dahiya, Zoe Hore, Federico Uchenna Stanley, Sara E. Jager, Franziska Denk, Peter Harley, Zhi Liang, Aleksandra Michrowska, Sara Villa-Hernandez, Federica La Russa

Publikováno v: Pain
bioRxiv
Biorxiv

Correct communication between immune cells and peripheral neurons is crucial for the protection of our bodies. Its breakdown is observed in many common, often painful conditions, including arthritis, neuropathies and inflammatory bowel or bladder dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a976aca1f3f9c63dc62058903150414d
https://doi.org/10.1101/813980

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Disruption of the Sensory System Affects Sterile Cutaneous Inflammation In Vivo

Autor: Stephen B. McMahon, Douglas M. Lopes, Susan D. Brain, David L.H. Bennett, Federica La Russa, Stuart Bevan, Carl Hobbs, Fulye Argunhan

Publikováno v: La Russa, F, Lopes, D M, Hobbs, C, Argunhan, F, Brain, S, Bevan, S, Bennett, D L H & McMahon, S B 2019, ' Disruption of the Sensory System Affects Sterile Cutaneous Inflammation In Vivo ', Journal of Investigative Dermatology, vol. 139, no. 9, pp. 1936-1945.e3 . https://doi.org/10.1016/j.jid.2019.01.037

Increasing evidence suggests that nerve fibers responding to noxious stimuli (nociceptors) modulate immunity in a variety of tissues, including the skin. Yet, the role of nociceptors in regulating sterile cutaneous inflammation remains unexplored. To

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f3cd1d6bcaec4acbe56f94ebda1fbd
https://kclpure.kcl.ac.uk/en/publications/2fdf1114-3287-4ef1-9ddb-9cecc2866453

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Large Scale

Autor: Kim I, Chisholm, Nikita, Khovanov, Douglas M, Lopes, Federica, La Russa, Stephen B, McMahon

Publikováno v: eNeuro

Greater emphasis on the study of intact cellular networks in their physiological environment has led to rapid advances in intravital imaging of the central nervous system (CNS), while the peripheral system remains largely unexplored. To assess large

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3f86c37a71e644fbf7585b8925727271
https://pubmed.ncbi.nlm.nih.gov/29662940

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Large scale in vivo recording of sensory neuron activity with GCaMP6

Autor: Nikita Khovanov, Kim I. Chisholm, Douglas M. Lopes, Stephen B. McMahon, Federica La Russa

Publikováno v: Chisholm, K I, Khovanov, N, De Medeiros Lopes, D, La Russa, F & McMahon, S 2018, ' Large scale in vivo recording of sensory neuron activity with GCaMP6 ', eNeuro, vol. 5, no. 1, NEURO.0417-17.2018 . https://doi.org/10.1523/ENEURO.0417-17.2018

Greater emphasis on the study of intact cellular networks in their physiological environment has led to rapid advances in intravital imaging in the central nervous system, while the peripheral system remains largely unexplored. To assess large networ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca7f89b76b9b5fa432b75f6765c527e
https://doi.org/10.1101/166959

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Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination

Autor: Ning Zhu, Federica La Russa, Remi Paramsothy, Christine A. Orengo, David L.H. Bennett, Alistair N. Garratt, Jorge Galino, Carmen Birchmeier, Ana Antunes-Martins, Florence R. Fricker, Jack Brelstaff, Stephen B. McMahon, James R. Perkins, Rebecca Goldberg

Publikováno v: Brain

Neuregulin 1 acts as an axonal signal that regulates multiple aspects of Schwann cell development including the survival and migration of Schwann cell precursors, the ensheathment of axons and subsequent elaboration of the myelin sheath. To examine t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647343883d5505e2b47ff3f7a0739532
http://europepmc.org/articles/PMC3692042

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Crosstalk between the nociceptive and immune systems in host defence and disease

Autor: David L.H. Bennett, Stephen B. McMahon, Federica La Russa

Publikováno v: Nature reviews. Neuroscience. 16(7)

Nociceptors and immune cells both protect the host from potential threats to homeostasis. There is growing evidence for bidirectional signalling between these two systems, and the underlying mechanisms are beginning to be elucidated. An understanding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4dbaffec9196b3003e2895b9b05eed
https://pubmed.ncbi.nlm.nih.gov/26087680

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Evaluation of tubulin polymerization and chronic inhibition of proteasome as citotoxicity mechanisms in bortezomib-induced peripheral neuropathy

Autor: Paola Marmiroli, Dana Foudah, Norberto Oggioni, Cristina Meregalli, Gabriella Nicolini, Guido Cavaletti, Federica La Russa, B Sala, Valentina Alda Carozzi, Alessia Chiorazzi, Cecilia Ceresa, Mariarosaria Miloso, David L.H. Bennett, Annalisa Canta, Matteo Colombo

Publikováno v: Cell cycle (Georgetown, Tex.). 13(4)

Bortezomib (BTZ) is the first proteasome inhibitor entered in clinical practice. Peripheral neuropathy is likely to be a class side effect of these drugs, although its severity is largely variable, and it deserves to be further investigated, since th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee3bef37a4fcbbcb0fb32453612210d
https://pubmed.ncbi.nlm.nih.gov/24335344

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Abstract 5679: Characterization in vivo of two different molecular mechanisms involved in the development of bortezomib-induced peripheral neuropathy

Autor: B Sala, Federica La Russa, Alessia Chiorazzi, Guido Cavaletti, Cristina Meregalli, Annalisa Canta

Publikováno v: Cancer Research. 72:5679-5679

Bortezomib (BTZ) is a chemotherapy drug with clinical efficacy in patients with relapsed/refractory, relapsed and newly diagnosed multiple mieloma (MM). It acts by inhibiting protein degradation by the proteasoma, but its clinical use is limited by a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3c73657f63a00e2474d6a8616a2735b
https://doi.org/10.1158/1538-7445.am2012-5679

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