Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Federica, Fusella"'
Autor:
Pietro Poggio, Stefania Rocca, Federica Fusella, Roberta Ferretti, Ugo Ala, Flora D’Anna, Emilia Giugliano, Cristina Panuzzo, Diletta Fontana, Valeria Palumbo, Giovanna Carrà, Daniela Taverna, Carlo Gambacorti-Passerini, Giuseppe Saglio, Carmen Fava, Rocco Piazza, Alessandro Morotti, Francesca Orso, Mara Brancaccio
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Morgana is a ubiquitous HSP90 co-chaperone protein coded by the CHORDC1 gene. Morgana heterozygous mice develop with age a myeloid malignancy resembling human atypical myeloid leukemia (aCML), now renamed MDS/MPN with neutrophilia. Patients
Externí odkaz:
https://doaj.org/article/6c827363c8c04882b2a5e5aa1fda4491
Autor:
Giovanna Carrà, Giuseppe Ermondi, Chiara Riganti, Luisella Righi, Giulia Caron, Alessio Menga, Enrica Capelletto, Beatrice Maffeo, Marcello Francesco Lingua, Federica Fusella, Marco Volante, Riccardo Taulli, Angelo Guerrasio, Silvia Novello, Mara Brancaccio, Rocco Piazza, Alessandro Morotti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Abstract Background Oxidative stress is a hallmark of many cancers. The increment in reactive oxygen species (ROS), resulting from an increased mitochondrial respiration, is the major cause of oxidative stress. Cell fate is known to be intricately li
Externí odkaz:
https://doaj.org/article/e99368fd3c9f4f83b919dcfdbb330f8a
Autor:
Federica Fusella, Laura Seclì, Elena Busso, Anna Krepelova, Enrico Moiso, Stefania Rocca, Laura Conti, Laura Annaratone, Cristina Rubinetto, Maurizia Mello-Grand, Vijay Singh, Giovanna Chiorino, Lorenzo Silengo, Fiorella Altruda, Emilia Turco, Alessandro Morotti, Salvatore Oliviero, Isabella Castellano, Federica Cavallo, Paolo Provero, Guido Tarone, Mara Brancaccio
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
NF-κB regulates inflammation, cell survival, proliferation, and metastasis and is often hyperactivated in triple-negative breast cancer. Here the authors show that Morgana, a protein highly expressed in triple-negative breast cancers, drives NF-kB a
Externí odkaz:
https://doaj.org/article/12fe3e6cb2cb4e56ad2f805e25c15661
Autor:
Mara Brancaccio, Federica Fusella, Federica Cavallo, Emilia Turco, Marco De Andrea, Alessandro Morotti, Valeria Poli, Emilio Hirsch, Barbara Miniscalco, Cristina Rubinetto, Giovanna Carrà, Andrea Iannucci, Laura Conti, Cristiana Cannata, Giuseppe Fragale, Pietro Poggio, Lidia Avalle, Laura Seclì
HSP90 is secreted by cancer cells into the extracellular milieu, where it exerts protumoral activities by activating extracellular substrate proteins and triggering autocrine signals through cancer cell surface receptors. Emerging evidence indicates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b556f26a72be2c6afd92ac456af30d9
https://doi.org/10.1158/0008-5472.c.6513151.v1
https://doi.org/10.1158/0008-5472.c.6513151.v1
Autor:
Mara Brancaccio, Federica Fusella, Federica Cavallo, Emilia Turco, Marco De Andrea, Alessandro Morotti, Valeria Poli, Emilio Hirsch, Barbara Miniscalco, Cristina Rubinetto, Giovanna Carrà, Andrea Iannucci, Laura Conti, Cristiana Cannata, Giuseppe Fragale, Pietro Poggio, Lidia Avalle, Laura Seclì
Supplementary Materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d53fc08b53f3f92944f8a3a5ab3a54c
https://doi.org/10.1158/0008-5472.22428814
https://doi.org/10.1158/0008-5472.22428814
Publikováno v:
Molecular & Cellular Oncology, Vol 5, Iss 3 (2018)
Cancer cells escape immune surveillance and induce immune cell aberrant activation to support tumour growth and progression. We recently reported that Morgana/NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) signaling in breast
Externí odkaz:
https://doaj.org/article/b74a8c6ae7544df19794e506ffcfbcd1
Publikováno v:
Cellular and Molecular Life Sciences
In addition to exerting several essential house-keeping activities in the cell, heat shock proteins (HSPs) are crucial players in a well-structured molecular program activated in response to stressful challenges. Among the different activities carrie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29de40e2ed921b73d393d75f96eae45f
https://doi.org/10.1007/s00018-021-03764-3
https://doi.org/10.1007/s00018-021-03764-3
Autor:
Manuela Iezzi, Annalisa Pezzolo, Ferdinando Di Cunto, Sara Cabodi, Alessandra Eva, Paola Defilippi, Alessandro Morellato, Silvia Grasso, Alessia Lamolinara, Davide Cangelosi, F. Bianchi, Iris Chiara Salaroglio, Andrea Saglietto, Luigi Varesio, Jennifer Chapelle, Valeria Poli, Chiara Riganti, Marzia Ognibene, Emilia Turco, Costanza Angelini, Federica Fusella, Vincenzo Salemme, Giorgia Centonze, Melissa Alzona
Publikováno v:
Cell Death and Differentiation
Neuroblastoma is the most common extra-cranial pediatric solid tumor, responsible for 13–15% of pediatric cancer death. Its intrinsic heterogeneity makes it difficult to target for successful therapy. The adaptor protein p140Cap/SRCIN1 negatively r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc04a57fecc738812cc725d6890f045f
http://europepmc.org/articles/PMC7205889
http://europepmc.org/articles/PMC7205889
Autor:
Federica Fusella, Rocco Piazza, Chiara Riganti, Marcello Francesco Lingua, Mara Brancaccio, Alessandro Morotti, Silvia Novello, Marco Volante, Alessio Menga, Enrica Capelletto, Angelo Guerrasio, Beatrice Maffeo, Luisella Righi, Giulia Caron, Riccardo Taulli, Giuseppe Ermondi, Giovanna Carrà
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
BackgroundOxidative stress is a hallmark of many cancers. The increment in reactive oxygen species (ROS), resulting from an increased mitochondrial respiration, is the major cause of oxidative stress. Cell fate is known to be intricately linked to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f73eb4b5803cb87aadee73015824a56
http://europepmc.org/articles/PMC8050912
http://europepmc.org/articles/PMC8050912
Autor:
Pietro Poggio, Laura Seclì, Cristiana Cannata, Lidia Avalle, Emilio Hirsch, Federica Cavallo, Giovanna Carrà, Laura Conti, Giuseppe Fragale, Cristina Rubinetto, Emilia Turco, Alessandro Morotti, Valeria Poli, Federica Fusella, Mara Brancaccio, Marco De Andrea, Barbara Miniscalco, Andrea Iannucci
HSP90 is secreted by cancer cells into the extracellular milieu, where it exerts protumoral activities by activating extracellular substrate proteins and triggering autocrine signals through cancer cell surface receptors. Emerging evidence indicates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049f1e0c2a44e05877e1a1c3890e2d9f
http://hdl.handle.net/2318/1806663
http://hdl.handle.net/2318/1806663