Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Federica, Bertaso"'
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Externí odkaz:
https://doaj.org/article/13ac4cdb6c4c4c2b831818add90a0d7d
Autor:
Nathalie Bouquier, Sophie Sakkaki, Fabrice Raynaud, Anne-Laure Hemonnot-Girard, Vincent Seube, Vincent Compan, Federica Bertaso, Julie Perroy, Enora Moutin
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
BackgroundShank3 is a scaffolding protein essential for the organization and function of the glutamatergic postsynapse. Monogenic mutations in SHANK3 gene are among the leading genetic causes of Autism Spectrum Disorders (ASD). The multiplicity of Sh
Externí odkaz:
https://doaj.org/article/3acb95849de64c3c87e8f9fa0d3fde40
Autor:
Benoit Girard, Pola Tuduri, Maria Paula Moreno, Sophie Sakkaki, Cedric Barboux, Tristan Bouschet, Annie Varrault, Jihane Vitre, Isabelle McCort-Tranchepain, Julien Dairou, Francine Acher, Laurent Fagni, Nicola Marchi, Julie Perroy, Federica Bertaso
Publikováno v:
Neurobiology of Disease, Vol 129, Iss , Pp 13-28 (2019)
Finding new targets to control or reduce seizure activity is essential to improve the management of epileptic patients. We hypothesized that activation of the pre-synaptic and inhibitory metabotropic glutamate receptor type 7 (mGlu7) reduces spontane
Externí odkaz:
https://doaj.org/article/989e0dcdf7ed41f0ab1a3772c10dfdc1
Autor:
Nathalie Bouquier, Benoit Girard, Juri Aparicio Arias, Laurent Fagni, Federica Bertaso, Julie Perroy
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
Epileptogenesis is the gradual process responsible for converting a healthy brain into an epileptic brain. This process can be triggered by a wide range of factors, including brain injury or tumors, infections, and status epilepticus. Epileptogenesis
Externí odkaz:
https://doaj.org/article/4f46577b1e1c4e70959f1ee1e63ef015
Autor:
Wendy Klement, Rita Garbelli, Emma Zub, Laura Rossini, Laura Tassi, Benoit Girard, Marine Blaquiere, Federica Bertaso, Julie Perroy, Frederic de Bock, Nicola Marchi
Publikováno v:
Neurobiology of Disease, Vol 113, Iss , Pp 70-81 (2018)
Background: Cerebrovascular dysfunction and inflammation occur in epilepsy. Here we asked whether pericytes, a pivotal cellular component of brain capillaries, undergo pathological modifications during experimental epileptogenesis and in human epilep
Externí odkaz:
https://doaj.org/article/108d8de664b84988b6ca28d0326f34bc
Autor:
Kevin Dorgans, Julie Salvi, Federica Bertaso, Ludivine Bernard, Philippe Lory, Frederic Doussau, Alexandre Mezghrani
Publikováno v:
Neurobiology of Disease, Vol 106, Iss , Pp 110-123 (2017)
Episodic Ataxia type 2 (EA2) is an autosomal dominant neuronal disorder linked to mutations in the Cav2.1 subunit of P/Q-type calcium channels. In vitro studies have established that EA2 mutations induce loss of channel activity and that EA2 mutants
Externí odkaz:
https://doaj.org/article/95d27118ac764f4fa5133ffc2df69352
Autor:
Nathalie, Bouquier, Sophie, Sakkaki, Fabrice, Raynaud, Anne-Laure, Hemonnot-Girard, Vincent, Seube, Vincent, Compan, Federica, Bertaso, Julie, Perroy, Enora, Moutin
Publikováno v:
Frontiers in neuroscience. 16
Shank3 is a scaffolding protein essential for the organization and function of the glutamatergic postsynapse. Monogenic mutations inIn this study, we created a novel transgenic mouse line, the Shank3We show that the endogenous Venus-Shank3a protein i
Autor:
Pauline Tarot, Laia Castell, Yuki Nakamura, Coline Rulhe, Juri Aparicio Arias, Laura Cutando, Federica Bertaso, Denis Hervé, Emmanuel Valjent
Publikováno v:
Neuroscience
Neuroscience, In press, 510, pp.9-20. ⟨10.1016/j.neuroscience.2022.12.005⟩
Neuroscience, In press, 510, pp.9-20. ⟨10.1016/j.neuroscience.2022.12.005⟩
International audience; Psychostimulant drugs, such as cocaine, d-amphetamine and methylphenidate, alter a wide range of behaviors including locomotor activity and somatosensory perception. These altered behaviors are accompanied by the activation of
Autor:
Julie Salvi, Federica Bertaso, Anne-Laure Mausset-Bonnefont, Alexandra Metz, Céline Lemmers, Fabrice Ango, Laurent Fagni, Philippe Lory, Alexandre Mezghrani
Publikováno v:
Neurobiology of Disease, Vol 68, Iss , Pp 47-56 (2014)
Episodic ataxia type-2 (EA2) is a dominantly inherited human neurological disorder caused by loss of function mutations in the CACNA1A gene, which encodes the CaV2.1 subunit of P/Q-type voltage-gated calcium channels. It remains however unknown wheth
Externí odkaz:
https://doaj.org/article/134a4839fbb746e09ea46831f9f608f2
Autor:
Benoît Girard, Jeanne Ster, Pola Tuduri, Maxime Thouaye, Enora Moutin, Nathalie Bouquier, Julie Perroy, Federica Bertaso
Publikováno v:
J Neurosci
Journal of Neuroscience
Journal of Neuroscience, 2022, 42 (47), pp.8897-8911. ⟨10.1523/JNEUROSCI.0063-22.2022⟩
Journal of Neuroscience
Journal of Neuroscience, 2022, 42 (47), pp.8897-8911. ⟨10.1523/JNEUROSCI.0063-22.2022⟩
Metabotropic glutamate receptor Type 3 (mGlu3) controls the sleep/wake architecture, which plays a role in the glutamatergic pathophysiology of schizophrenia. Interestingly, mGlu3 receptor expression is decreased in the brain of schizophrenic patient