Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Fedele, Bonifazi"'
Autor:
Muhammad Aminu Idris, Lucia Ruggieri, Hafsat Rufai Ahmad, Abdulaziz Hassan, Ismaila Nda Ibrahim, Faruk Jamil Adullahi, Sani Awwalu, Usman Nasiru, Fedele Bonifazi, Baba P. D. Inusa
Publikováno v:
Hemato, Vol 5, Iss 3, Pp 340-349 (2024)
Background: Sickle cell disease (SCD) is an autosomal recessive haemoglobin disorder, affecting about 7.74 million individuals worldwide, but it is more prevalent among Africans and Asians. SCD is characterised by many complications, and it is a majo
Externí odkaz:
https://doaj.org/article/912734993ef243619b1d13c6bca9b31d
Autor:
Petros Kountouris, Coralea Stephanou, Maxwell Nwegbu, Obiageli Nnodu, Morohuntodun Oni, Natasha Archer, Leon Tshilolo, Bin Alwi Zilfalil, Kyriaki Michailidou, Viviana Giannuzzi, Fedele Bonifazi, Marina Kleanthous
Publikováno v:
HemaSphere, Vol 7, p e22097c3 (2023)
Externí odkaz:
https://doaj.org/article/72fe500010074d889b99ecfca556b470
Autor:
Anando Sen, Victoria Hedley, Eva Degraeuwe, Steven Hirschfeld, Ronald Cornet, Ramona Walls, John Owen, Peter N. Robinson, Edward G. Neilan, Thomas Liener, Giovanni Nisato, Neena Modi, Simon Woodworth, Avril Palmeri, Ricarda Gaentzsch, Melissa Walsh, Teresa Berkery, Joanne Lee, Laura Persijn, Kasey Baker, Kristina An Haack, Sonia Segovia Simon, Julius O. B. Jacobsen, Giorgio Reggiardo, Melissa A. Kirwin, Jessie Trueman, Claudia Pansieri, Donato Bonifazi, Sinéad Nally, Fedele Bonifazi, Rebecca Leary, Volker Straub
Publikováno v:
Data, Vol 9, Iss 4, p 55 (2024)
The conect4children (c4c) initiative was established to facilitate the development of new drugs and other therapies for paediatric patients. It is widely recognised that there are not enough medicines tested for all relevant ages of the paediatric po
Externí odkaz:
https://doaj.org/article/e7a77672ae75448a8d6368c5e0e60542
Autor:
Mariagrazia Felisi, Fedele Bonifazi, Maddalena Toma, Claudia Pansieri, Rebecca Leary, Victoria Hedley, Ronald Cornet, Giorgio Reggiardo, Annalisa Landi, Annunziata D’Ercole, Salma Malik, Sinéad Nally, Anando Sen, Avril Palmeri, Donato Bonifazi, Adriana Ceci
Publikováno v:
Data, Vol 9, Iss 4, p 59 (2024)
The reuse of paediatric individual patient data (IPD) from clinical trials (CTs) is essential to overcome specific ethical, regulatory, methodological, and economic issues that hinder the progress of paediatric research. Sharing data through reposito
Externí odkaz:
https://doaj.org/article/9158e49a93a246568a90d8f1c50b1cc2
Autor:
Adriana Ceci, Rosa Conte, Antonella Didio, Annalisa Landi, Lucia Ruggieri, Viviana Giannuzzi, Fedele Bonifazi
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionSeveral new active substances (ASs) targeting neuroblastoma (NBL) are under study. We aim to describe the developmental and regulatory status of a sample of ASs targeting NBL to underline the existing regulatory gaps in product developmen
Externí odkaz:
https://doaj.org/article/b7c476e27a844123afb4d8c3837fe18c
Random Forest Clustering Identifies Three Subgroups of β-Thalassemia with Distinct Clinical Severity
Autor:
Angela Vitrano, Khaled M. Musallam, Antonella Meloni, Sebastiano Addario Pollina, Mehran Karimi, Amal El-Beshlawy, Mahmoud Hajipour, Vito Di Marco, Saqib Hussain Ansari, Aldo Filosa, Paolo Ricchi, Adriana Ceci, Shahina Daar, Efthymia Vlachaki, Sylvia Titi Singer, Zaki A. Naserullah, Alessia Pepe, Salvatore Scondotto, Gabriella Dardanoni, Fedele Bonifazi, Vijay G. Sankaran, Elliott Vichinsky, Ali T. Taher, Aurelio Maggio, International Working Group on Thalassemia (IWG-THAL)
Publikováno v:
Thalassemia Reports, Vol 12, Iss 1, Pp 14-23 (2022)
In this work, we aimed to establish subgroups of clinical severity in a global cohort of β-thalassemia through unsupervised random forest (RF) clustering. We used a large global dataset of 7910 β-thalassemia patients and evaluated 19 indicators of
Externí odkaz:
https://doaj.org/article/aa15c48822b849b987d37e3cf47bfde0
Autor:
Khaled M. Musallam, Angela Vitrano, Antonella Meloni, Sebastiano Addario Pollina, Mehran Karimi, Amal El-Beshlawy, Mahmoud Hajipour, Vito Di Marco, Saqib Hussain Ansari, Aldo Filosa, Paolo Ricchi, Adriana Ceci, Shahina Daar, Efthymia Vlachaki, Sylvia Titi Singer, Zaki A. Naserullah, Alessia Pepe, Salvatore Scondotto, Gabriella Dardanoni, Fedele Bonifazi, Vijay G. Sankaran, Elliott Vichinsky, Ali T. Taher, Aurelio Maggio
Publikováno v:
Haematologica, Vol 106, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/f8aa168aaecb4973892659488df605a9
Autor:
Annalisa Landi, Mark Thompson, Viviana Giannuzzi, Fedele Bonifazi, Ignasi Labastida, Luiz Olavo Bonino da Silva Santos, Marco Roos
Publikováno v:
Data Intelligence, Vol 2, Iss 1-2 (2021)
Externí odkaz:
https://doaj.org/article/ab05e51cc7684d05b0fc47ee3ac7791c
Autor:
Maddalena Toma, Mariagrazia Felisi, Donato Bonifazi, Fedele Bonifazi, Viviana Giannuzzi, Giorgio Reggiardo, Saskia de Wildt, Adriana Ceci, TEDDY European Network of Excellence for Paediatric Research
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Objectives: In this paper, we investigated the effects of the European Paediatric Regulation (EC) N° 1901/2006 with respect to satisfying the paediatric therapeutic needs, assessed in terms of the increased number of paediatric medicinal products, n
Externí odkaz:
https://doaj.org/article/21996e36f4954970a9d231bc8c69ed5e
Autor:
Paul Dimitri, Valeria Pignataro, Mariangela Lupo, Donato Bonifazi, Maria Henke, Umberto M. Musazzi, Floris Ernst, Paola Minghetti, Davide F. Redaelli, Sophia G. Antimisiaris, Giovanni Migliaccio, Fedele Bonifazi, Luca Marciani, Aaron J. Courtenay, Nunzio Denora, Angela Lopedota
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2178 (2021)
Development of specific medical devices (MDs) is required to meet the healthcare needs of children and young people (CYP). In this context, MD development should address changes in growth and psychosocial maturation, physiology, and pathophysiology,
Externí odkaz:
https://doaj.org/article/f31aedb629d6404a9d8584176e80d34f