Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Fearnside JF"'
1
Microbial-host co-metabolites are prodromal markers predicting phenotypic heterogeneity in behavior, obesity, and impaired glucose tolerance
Autor: Dumas, M-E, Rothwell, AR, Hoyles, L, Aranias, T, Chilloux, J, Calderari, S, Noll, EM, Péan, N, Boulangé, CL, Blancher, C, Barton, RH, Gu, Q, Fearnside, JF, Deshayes, C, Hue, C, Scott, J, Nicholson, JK, Gauguier, D
Publikováno v: Cell Reports
Cell Reports, 2017, 20 (1), pp.136-148. ⟨10.1016/j.celrep.2017.06.039⟩
Cell Reports, Elsevier Inc, 2017, 20 (1), pp.136-148. ⟨10.1016/j.celrep.2017.06.039⟩
Cell Reports, Vol 20, Iss 1, Pp 136-148 (2017)
Summary The influence of the gut microbiome on metabolic and behavioral traits is widely accepted, though the microbiome-derived metabolites involved remain unclear. We carried out untargeted urine 1H-NMR spectroscopy-based metabolic phenotyping in a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8ade711b283e249f5aa41ce1fbcf5134
https://ora.ox.ac.uk/objects/uuid:bb30e12a-8ecc-4451-9fa6-5cfb552927b3
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2
Gut microbial metabolomic predictors of dietary-induced obesity and diabetes
Autor: Marc-Emmanuel Dumas, Hoyles, L., Chilloux, J., Calderari, S., Rothwell, A., Boulange, Cl, Gu, Q., Hue, C., Fearnside, Jf, Scott, J., Nicholson, Jk, Gauguier, D.
Publikováno v: 74. American Diabetes Association
74. American Diabetes Association, Jun 2014, San Francisco, United States. American Diabetes Association, Diabetes, 63 (S1), 2014, 74th American Diabetes Association. ⟨10.2337/db14-1741-2092⟩
CIÊNCIAVITAE
ResearcherID
International audience; Phenotype heterogeneity is classically infl uenced by genetic, epigenetic and environmental factors but the gut microbiome is also thought to contribute to this phenomenon. Here we studied a population of 50 isogenic C57BL/6J
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::90115a32516e789eefa3a0944a44f1ac
https://hal.inrae.fr/hal-02741047
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4
Akademický článek
Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment.
Autor: Brial F; Sorbonne University, University Paris Descartes, University Paris Diderot, INSERM UMR_S 1138, Cordeliers Research Centre, 75006, Paris, France., Le Lay A; Sorbonne University, University Paris Descartes, University Paris Diderot, INSERM UMR_S 1138, Cordeliers Research Centre, 75006, Paris, France., Hedjazi L; Sorbonne University, University Paris Descartes, University Paris Diderot, INSERM UMR_S 1138, Cordeliers Research Centre, 75006, Paris, France., Tsang T; Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, SW7 2AZ, United Kingdom., Fearnside JF; School of Health and Related Research, The University of Sheffield, 30 Regent Court, Sheffield, S10 2TA, United Kingdom., Otto GW; Genetics and Genomic Medicine, University College London Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, United Kingdom., Alzaid F; Sorbonne University, University Paris Descartes, University Paris Diderot, INSERM UMR_S 1138, Cordeliers Research Centre, 75006, Paris, France., Wilder SP; The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, OX3 7BN, United Kingdom.; Genomics Plc, King Charles House, Oxford, Park End Street, OX1 1JD, United Kingdom., Venteclef N; Sorbonne University, University Paris Descartes, University Paris Diderot, INSERM UMR_S 1138, Cordeliers Research Centre, 75006, Paris, France., Cazier JB; Centre for Computational Biology, Medical School, University of Birmingham, Birmingham, B15 2TT, United Kingdom., Nicholson JK; Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, SW7 2AZ, United Kingdom.; The Australian National Phenome Centre, Murdoch University, Perth, WA6150, Australia., Day C; Faculty of Medical Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, United Kingdom., Burt AD; Faculty of Medical Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, United Kingdom.; Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, 5005, Australia., Gut IG; CNAG-CRG, Centre for Genomic Regulation, Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 4, 08028, Barcelona, Spain., Lathrop M; McGill University and Genome Quebec Innovation Centre, 740 Doctor Penfield Avenue, Montreal, QC, H3A 0G1, Canada., Dumas ME; Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, SW7 2AZ, United Kingdom.; McGill University and Genome Quebec Innovation Centre, 740 Doctor Penfield Avenue, Montreal, QC, H3A 0G1, Canada., Gauguier D; Sorbonne University, University Paris Descartes, University Paris Diderot, INSERM UMR_S 1138, Cordeliers Research Centre, 75006, Paris, France. dominique.gauguier@inserm.fr.; Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, SW7 2AZ, United Kingdom. dominique.gauguier@inserm.fr.; The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, OX3 7BN, United Kingdom. dominique.gauguier@inserm.fr.; McGill University and Genome Quebec Innovation Centre, 740 Doctor Penfield Avenue, Montreal, QC, H3A 0G1, Canada. dominique.gauguier@inserm.fr.
Publikováno v: Scientific reports [Sci Rep] 2019 Mar 06; Vol. 9 (1), pp. 3656. Date of Electronic Publication: 2019 Mar 06.
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5
Akademický článek
Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance.
Autor: Dumas ME; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK. Electronic address: m.dumas@imperial.ac.uk., Rothwell AR; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Hoyles L; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Aranias T; Cordeliers Research Centre, INSERM UMR_S 1138, University Pierre & Marie Curie and University Paris Descartes, Sorbonne Paris Cité, Sorbonne Universities, 15 Rue de l'École de Médecine, 75006 Paris, France., Chilloux J; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Calderari S; Cordeliers Research Centre, INSERM UMR_S 1138, University Pierre & Marie Curie and University Paris Descartes, Sorbonne Paris Cité, Sorbonne Universities, 15 Rue de l'École de Médecine, 75006 Paris, France., Noll EM; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Péan N; Cordeliers Research Centre, INSERM UMR_S 1138, University Pierre & Marie Curie and University Paris Descartes, Sorbonne Paris Cité, Sorbonne Universities, 15 Rue de l'École de Médecine, 75006 Paris, France., Boulangé CL; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Blancher C; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Barton RH; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Gu Q; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Fearnside JF; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Deshayes C; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Hue C; Cordeliers Research Centre, INSERM UMR_S 1138, University Pierre & Marie Curie and University Paris Descartes, Sorbonne Paris Cité, Sorbonne Universities, 15 Rue de l'École de Médecine, 75006 Paris, France., Scott J; Department of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK., Nicholson JK; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Gauguier D; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Cordeliers Research Centre, INSERM UMR_S 1138, University Pierre & Marie Curie and University Paris Descartes, Sorbonne Paris Cité, Sorbonne Universities, 15 Rue de l'École de Médecine, 75006 Paris, France. Electronic address: dominique.gauguier@crc.jussieu.fr.
Publikováno v: Cell reports [Cell Rep] 2017 Jul 05; Vol. 20 (1), pp. 136-148.
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6
Akademický článek
Broad-ranging natural metabotype variation drives physiological plasticity in healthy control inbred rat strains.
Autor: Pontoizeau C; Centre de Résonance Magnétique Nucléaire à Très Hauts Champs, FRE 3008, 5 rue de la Doua, 69100 Villeurbanne, France., Fearnside JF, Navratil V, Domange C, Cazier JB, Fernández-Santamaría C, Kaisaki PJ, Emsley L, Toulhoat P, Bihoreau MT, Nicholson JK, Gauguier D, Dumas ME
Publikováno v: Journal of proteome research [J Proteome Res] 2011 Apr 01; Vol. 10 (4), pp. 1675-89. Date of Electronic Publication: 2011 Mar 15.
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7
Akademický článek
Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice.
Autor: Fearnside JF; The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Dumas ME, Rothwell AR, Wilder SP, Cloarec O, Toye A, Blancher C, Holmes E, Tatoud R, Barton RH, Scott J, Nicholson JK, Gauguier D
Publikováno v: PloS one [PLoS One] 2008 Feb 27; Vol. 3 (2), pp. e1668. Date of Electronic Publication: 2008 Feb 27.
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8
Akademický článek
Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice.
Autor: Toye AA; The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK., Dumas ME; Department of Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Faculty of Medicine, Imperial College London, London, UK., Blancher C; The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK., Rothwell AR; The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK., Fearnside JF; The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK., Wilder SP; The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK., Bihoreau MT; The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK., Cloarec O; Department of Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Faculty of Medicine, Imperial College London, London, UK., Azzouzi I; The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK., Young S; The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK., Barton RH; Department of Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Faculty of Medicine, Imperial College London, London, UK., Holmes E; Department of Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Faculty of Medicine, Imperial College London, London, UK., McCarthy MI; The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK., Tatoud R; Faculty of Medicine, Imperial College London, London, UK., Nicholson JK; Department of Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Faculty of Medicine, Imperial College London, London, UK., Scott J; Faculty of Medicine, Imperial College London, London, UK., Gauguier D; The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK. gdomi@well.ox.ac.uk.
Publikováno v: Diabetologia [Diabetologia] 2007 Sep; Vol. 50 (9), pp. 1867-1879. Date of Electronic Publication: 2007 Jul 06.
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9
Akademický článek
Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models.
Autor: Dumas ME; Imperial College London, Department of Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Faculty of Medicine, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Wilder SP, Bihoreau MT, Barton RH, Fearnside JF, Argoud K, D'Amato L, Wallis RH, Blancher C, Keun HC, Baunsgaard D, Scott J, Sidelmann UG, Nicholson JK, Gauguier D
Publikováno v: Nature genetics [Nat Genet] 2007 May; Vol. 39 (5), pp. 666-72. Date of Electronic Publication: 2007 Apr 15.
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