Zobrazeno 1 - 10
of 788
pro vyhledávání: '"Félix Hernández"'
Autor:
Julia Sala-Jarque, Vanessa Gil, Pol Andrés-Benito, Inés Martínez-Soria, Pol Picón-Pagès, Félix Hernández, Jesús Ávila, José Luis Lanciego, Mario Nuvolone, Adriano Aguzzi, Rosalina Gavín, Isidro Ferrer, José Antonio del Río
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The cellular prion protein (PrPC) plays many roles in the developing and adult brain. In addition, PrPC binds to several amyloids in oligomeric and prefibrillar forms and may act as a putative receptor of abnormal misfolded protein species.
Externí odkaz:
https://doaj.org/article/2f78e00735454e27858d150cc64c59b9
Autor:
Alejandro Antón-Fernández, Marta Roldán-Lázaro, Laura Vallés-Saiz, Jesús Ávila, Félix Hernández
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract In recent years, there has been success in partially reprogramming peripheral organ cells using cyclic Yamanaka transcription factor (YF) expression, resulting in the reversal of age-related pathologies. In the case of the brain, the effects
Externí odkaz:
https://doaj.org/article/dd6086151fdd40d980fb4c6630699948
Autor:
Daniel Ruiz-Gabarre, Laura Vallés-Saiz, Almudena Carnero-Espejo, Isidro Ferrer, Félix Hernández, Ramon Garcia-Escudero, Jesús Ávila, Vega García-Escudero
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104953- (2024)
Summary: Background: Tau is a microtubule-binding protein encoded by the MAPT gene. Tau is essential for several physiological functions and associated with pathological processes, including Alzheimer's disease (AD). Six tau isoforms are typically de
Externí odkaz:
https://doaj.org/article/3c206599cfbe491f8d0c10951fc2ef7c
Publikováno v:
Exploration of Neuroprotective Therapy, Vol 3, Iss 3, Pp 151-163 (2023)
Currently, the predominant targets for the treatment of Alzheimer’s disease (AD) are the main components of the two pathological structures: senile plaques (composed of amyloid beta peptide aggregates) or neurofibrillary tangles (constructed of tau
Externí odkaz:
https://doaj.org/article/8eb672ef8ca543819b11826548868031
Autor:
Pedro Madrigal, Nitin K. Singh, Jason M. Wood, Elena Gaudioso, Félix Hernández-del-Olmo, Christopher E. Mason, Kasthuri Venkateswaran, Afshin Beheshti
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract Background Antimicrobial resistance (AMR) has a detrimental impact on human health on Earth and it is equally concerning in other environments such as space habitat due to microgravity, radiation and confinement, especially for long-distance
Externí odkaz:
https://doaj.org/article/1ee3d7c2ad254597850717056f0b3274
Autor:
Roque Serrano, Juan C. Navarro, Carlos Sales, Tania Portolés, Óscar Monroig, Joaquin Beltran, Félix Hernández
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Very long-chain (> C24) polyunsaturated fatty acids (VLC-PUFA) play an important role in the development of nervous system, retinal function and reproductive processes in vertebrates. Their presence in very small amounts in specific lipid cl
Externí odkaz:
https://doaj.org/article/16980f5de4e44009b497742467f78a8d
Autor:
Juan R. Perea, Esther García, Laura Vallés-Saiz, Raquel Cuadros, Félix Hernández, Marta Bolós, Jesús Avila
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Tauopathies are a group of neurodegenerative diseases characterized by the accumulation of hyperphosphorylated tau protein in the brain. Many of these pathologies also present an inflammatory component determined by the activation of microgl
Externí odkaz:
https://doaj.org/article/9799048a1e7449c4a843344f9a985dc8
Autor:
David Fabregat-Safont, María Mata-Pesquera, Manuela Barneo-Muñoz, Ferran Martinez-Garcia, Marie Mardal, Anders B. Davidsen, Juan V. Sancho, Félix Hernández, María Ibáñez
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Synthetic cannabinoids are amongst the most widely used psychoactive drugs which are tightly controlled by government agencies around the world. Here, pharmacokinetics of two synthetic cannabinoids in rats are evaluated along with their metabolites a
Externí odkaz:
https://doaj.org/article/7d250282741a4a2d980a0608500a1262
Autor:
Félix Hernández del Ángel
Publikováno v:
Oficio, Revista de Historia e Interdisciplina, Pp 51-68 (2022)
Este artículo analiza algunos periódicos que Juan Bautista Morales editó y publicó en la primera mitad del siglo XIX en México y tiene el propósito de ofrecer al lector una gama de contenidos posible de profundizar para el estudio crítico del
Externí odkaz:
https://doaj.org/article/940b489fa4ea45d088e4cf8fbe8f7596
Autor:
Efraím A. Serna-Galvis, Javier Silva-Agredo, Félix Hernández, Ana M. Botero-Coy, Ricardo A. Torres-Palma
Publikováno v:
MethodsX, Vol 10, Iss , Pp 102128- (2023)
A primary pollution source by pharmaceuticals is hospital wastewater (HWW). Herein, the methods involved in the action of a biological system (BS, aerobic activated sludge) or a sonochemical treatment (US, 375 kHz and 30.8 W), for degrading four rele
Externí odkaz:
https://doaj.org/article/f86e3c17a0ec4d69bd90598fc7ff055f