Zobrazeno 1 - 10
of 1 544
pro vyhledávání: '"Fc gamma receptors"'
Autor:
Ryan Haryadi, Kah Fai Chan, Pao Chun Lin, Yun Lei Tan, Corrine Wan, Wahyu Shahreel, Shi Jie Tay, Terry Nguyen-Khuong, Ian Walsh, Zhiwei Song
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract This report describes the development and characterization of a comprehensive collection of CHO cell glycosylation mutants with significant potential for advancing glycobiology and biotechnology. EPO-Fc and trastuzumab, two model molecules,
Externí odkaz:
https://doaj.org/article/75542e73d23a4b45832f4c42a7c4b5fe
Autor:
Xiaoke Yang, Encheng Sun, Huanjie Zhai, Tao Wang, Shida Wang, Yuxuan Gao, Qinghe Hou, Xiangyu Guan, Shuwen Li, Lian-Feng Li, Hongxia Wu, Yuzi Luo, Su Li, Yuan Sun, Dongming Zhao, Yongfeng Li, Hua-Ji Qiu
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
African swine fever virus (ASFV) is the causative agent of African swine fever (ASF), a highly contagious disease that can kill up to 100% of domestic pigs and wild boars. It has been shown that the pigs inoculated with some ASF vaccine candidates di
Externí odkaz:
https://doaj.org/article/b5644145ef9b45febdb375453404ff70
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Recombinant Factor VIII-Fc fusion protein (rFVIIIFc) is an enhanced half-life therapeutic protein product used for the management of hemophilia A. Recent studies have demonstrated that rFVIIIFc interacts with Fc gamma receptors (FcγR) resulting in t
Externí odkaz:
https://doaj.org/article/2ae01388a1334f9cb319d59268a22ae9
Akademický článek
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Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
It is well established that immunoglobulin E (IgE) plays a crucial role in atopy by binding to two types of Fcε receptors (FcεRI and FcεRII, also known as CD23). The cross-linking of FcεRI-bound IgE on effector cells, such as basophils and mast c
Externí odkaz:
https://doaj.org/article/34b18a2486e745669094c2603f3751f4
Autor:
Khiyam Hussain, Rena Liu, Rosanna C. G. Smith, Kri T. J. Müller, Mohammadmersad Ghorbani, Sofia Macari, Kirstie L. S. Cleary, Robert J. Oldham, Russell B. Foxall, Sonya James, Steven G. Booth, Tom Murray, Lekh N. Dahal, Chantal E. Hargreaves, Robert S. Kemp, Jemma Longley, James Douglas, Hannah Markham, Serena J. Chee, Richard J. Stopforth, Ali Roghanian, Matthew J. Carter, Christian H. Ottensmeier, Bjorn Frendéus, Ramsey I. Cutress, Ruth R. French, Martin J. Glennie, Jonathan C. Strefford, Stephen M. Thirdborough, Stephen A. Beers, Mark S. Cragg
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-32 (2022)
Abstract Background Hypoxia is a hallmark of the tumor microenvironment (TME) and in addition to altering metabolism in cancer cells, it transforms tumor-associated stromal cells. Within the tumor stromal cell compartment, tumor-associated macrophage
Externí odkaz:
https://doaj.org/article/4a2581bb496d4f649850cb54190883b9
Akademický článek
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Autor:
Haizhang Chen, Andrea Maul‐Pavicic, Martin Holzer, Magdalena Huber, Ulrich Salzer, Nina Chevalier, Reinhard E Voll, Hartmut Hengel, Philipp Kolb
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 1, Pp 1-17 (2021)
Abstract Fc‐gamma receptor (FcγR) activation by soluble IgG immune complexes (sICs) represents a major mechanism of inflammation in certain autoimmune diseases such as systemic lupus erythematosus (SLE). A robust and scalable test system allowing
Externí odkaz:
https://doaj.org/article/d3c81898e97a42de975a99761a93314a
Autor:
Artur Summerfield, Heidi Gerber, Rebeka Schmitt, Matthias Liniger, Santina Grazioli, Emiliana Brocchi
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Previous studies demonstrated that polyclonal antibodies against foot-and-mouth disease virus (FMDV) generated by vaccination can mediate immune functions not only through virus neutralization but also through promoting virus uptake by macrophages an
Externí odkaz:
https://doaj.org/article/edef8dd9d7b64ba0a1e60eb3f95fde01
Autor:
Julie Van Coillie, Morten A. Schulz, Arthur E. H. Bentlage, Noortje de Haan, Zilu Ye, Dionne M. Geerdes, Wim J. E. van Esch, Lise Hafkenscheid, Rebecca L. Miller, Yoshiki Narimatsu, Sergey Y. Vakhrushev, Zhang Yang, Gestur Vidarsson, Henrik Clausen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immunoglobulins G (IgG) and their Fc gamma receptors (FcγRs) play important roles in our immune system. The conserved N-glycan in the Fc region of IgG1 impacts interaction of IgG with FcγRs and the resulting effector functions, which has led to the
Externí odkaz:
https://doaj.org/article/d3ca065183164628bb92e4118236f671