Zobrazeno 1 - 10
of 1 837
pro vyhledávání: '"Fc effector function"'
Akademický článek
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Autor:
Jennifer L. Schwedler, Maxwell A. Stefan, Christine E. Thatcher, Peter R. McIlroy, Anupama Sinha, Ashlee M. Phillips, Christopher A. Sumner, Colleen M. Courtney, Christina Y. Kim, Dina R. Weilhammer, Brooke Harmon
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTThe development of specific, safe, and potent monoclonal antibodies (Abs) has led to novel therapeutic options for infectious disease. In addition to preventing viral infection through neutralization, Abs can clear infected cells and induce i
Externí odkaz:
https://doaj.org/article/41cb4663916447a9b561b48ff9e50a25
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Akademický článek
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Autor:
Martineau R; Université Paris Saclay, Le Kremlin-Bicetre, France.; Centre d'Investigation Clinique BIOTHERIS, CIC 1428, Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France., Susini S; Centre d'Investigation Clinique BIOTHERIS, CIC 1428, Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France.; Translational Immunotherapy Research Laboratory, Gustave Roussy, Villejuif, France., Marabelle A; Université Paris Saclay, Le Kremlin-Bicetre, France.; Centre d'Investigation Clinique BIOTHERIS, CIC 1428, Institut National de la Santé et de la Recherche Médicale (INSERM), Villejuif, France.; Translational Immunotherapy Research Laboratory, Gustave Roussy, Villejuif, France.
Publikováno v:
Immunological reviews [Immunol Rev] 2024 Dec 11. Date of Electronic Publication: 2024 Dec 11.
Autor:
Callahan V; Emerging Virus Immunity Unit, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Sutton MS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Gardner CL; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ft. Detrick, MD, USA., Kenchegowda D; Emerging Virus Immunity Unit, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Dunagan MM; Emerging Virus Immunity Unit, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Gosavi M; Emerging Virus Immunity Unit, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Green C; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Chen TY; Emerging Virus Immunity Unit, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Prado-Smith J; Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America., Long D; Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America., Vogel JL; Molecular Genetics Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Kristie TM; Molecular Genetics Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Clancy CS; Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America., Burke CW; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ft. Detrick, MD, USA., Roederer M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Fox JM; Emerging Virus Immunity Unit, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 03. Date of Electronic Publication: 2024 Nov 03.
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Recombinant Factor VIII-Fc fusion protein (rFVIIIFc) is an enhanced half-life therapeutic protein product used for the management of hemophilia A. Recent studies have demonstrated that rFVIIIFc interacts with Fc gamma receptors (FcγR) resulting in t
Externí odkaz:
https://doaj.org/article/2ae01388a1334f9cb319d59268a22ae9
Akademický článek
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Autor:
William D. Tolbert, Dung N. Nguyen, Marina Tuyishime, Andrew R. Crowley, Yaozong Chen, Shalini Jha, Derrick Goodman, Valerie Bekker, Sarah V. Mudrak, Anthony L. DeVico, George K. Lewis, James F. Theis, Abraham Pinter, M. Anthony Moody, David Easterhoff, Kevin Wiehe, Justin Pollara, Kevin O. Saunders, Georgia D. Tomaras, Margaret Ackerman, Guido Ferrari, Marzena Pazgier
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Passive transfer of monoclonal antibodies (mAbs) of human origin into Non-Human Primates (NHPs), especially those which function predominantly by a Fc-effector mechanism, requires an a priori preparation step, in which the human mAb is reengineered t
Externí odkaz:
https://doaj.org/article/ebe45cad4e6d401b8cdeec5671af1e07
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