Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Faye Wang"'
Publikováno v:
IEEE Access, Vol 10, Pp 53761-53776 (2022)
Terahertz (THz) radiation ( $0.1\sim 10$ THz) shows great potential in agricultural products detection, biomedical, and security inspection in recent years. Machine learning methods are widely used to support the user demand of higher efficiency and
Externí odkaz:
https://doaj.org/article/8a574ecda7d24231a58bd6e0f6bb7b84
Autor:
Faye Wang, Cindy Zhang, Jae Kwagh, Brian Strassle, Jinqing Li, Minxue Huang, Yunling Song, Brenda Lehman, Richard Westhouse, Kamalavenkatesh Palanisamy, Vinay K. Holenarsipur, Robert Borzilleri, Karen Augustine-Rauch
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102133- (2021)
Summary: This study focused on characterizing the potential mechanism of valvular toxicity caused by TGFβ receptor inhibitors (TGFβRis) using rat valvular interstitial cells (VICs) to evaluate early biological responses to TGFβR inhibition. Three
Externí odkaz:
https://doaj.org/article/a68cd93dd958438cb620f93aecf70450
Autor:
Richard A. Westhouse, Faye Wang, Jae Kwagh, Brian Strassle, Cindy X. Zhang, Robert M. Borzilleri, Minxue Huang, Vinay K. Holenarsipur, Yunling Song, Kamalavenkatesh Palanisamy, Karen Augustine-Rauch, Jinqing Li, Brenda L. Lehman
Publikováno v:
iScience
iScience, Vol 24, Iss 3, Pp 102133-(2021)
iScience, Vol 24, Iss 3, Pp 102133-(2021)
Summary This study focused on characterizing the potential mechanism of valvular toxicity caused by TGFβ receptor inhibitors (TGFβRis) using rat valvular interstitial cells (VICs) to evaluate early biological responses to TGFβR inhibition. Three T
Autor:
Celia D’Arienzo, Ananta Karmakar, Marta Dabros, Michael Galella, Jingwu Duan, John S. Sack, Dhanya Kumar Raut, David S. Weinstein, Andrew T. Pudzianowski, Ding-Ren Shen, Sylwia Stachura, Joel C. Barrish, Arun Kumar Gupta, Huadong Sun, William R. Foster, Javed Khan, Melissa Yarde, Dan Camac, Lauren Haque, Qihong Zhao, Dauh-Rurng Wu, Carolyn A. Weigelt, Faye Wang, Percy H. Carter, Luisa Salter-Cid, Hemalatha Hemagiri, Jenny Xie, T. G. Murali Dhar, Zhonghui Lu, Virna Borowski, Hua Gong, John E. Somerville
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:85-93
We disclose the optimization of a high throughput screening hit to yield benzothiazine and tetrahydroquinoline sulfonamides as potent RORγt inverse agonists. However, a majority of these compounds showed potent activity against pregnane X receptor (
Autor:
Yuhe Faye Wang
Publikováno v:
Qui Parle. 26:535-552
Autor:
Marc H. Davies, Megan Fuller, Jamie J. Arnold, Craig E. Cameron, Terry Van Vleet, Michael J. Graziano, Thomas P. Sanderson, Damir Simic, Chris Storck, Catherine Euler, Oliver P. Flint, Bethany R. Baumgart, Suresh D. Sharma, Faye Wang, Roderick T. Bunch, Jae Kwagh
Publikováno v:
Toxicological Sciences
BMS-986094, the prodrug of a guanosine nucleotide analogue (2'-C-methylguanosine), was withdrawn from clinical trials due to serious safety issues. Nonclinical investigative studies were conducted as a follow up to evaluate the potential for BMS-9860
Autor:
Seth Schulman, Huifen Faye Wang, Feng Qiu, Xiongfe Wu, Penelope Crownover, Joan M. Korth-Bradley, Juanzhi Fang
Publikováno v:
Clinical Pharmacology in Drug Development. 3:235-241
This open-label, nonrandomized study was conducted to evaluate the steady-state pharmacokinetics of sirolimus in 24 stable Chinese renal transplant patients receiving daily oral maintenance doses of sirolimus (1-4 mg). Repeated trough and serial whol
Autor:
Alaric J. Dyckman, Paul Levesque, Minxue Huang, Faye Wang, Lois D. Lehman-McKeeman, Geoff Lewen, Hong Shi, Jae Kwagh, Jenny Xie
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 88:242-243
Autor:
Dagmara Szkolnicka, Ferdous Khan, Baltasar Lucendo-Villarin, Claire N. Medine, Faye Wang, David C. Hay, James A. Ross, Howard M. Marriage, John P. Iredale, Mark Bradley, James R M Black, Oliver P. Flint, Salvatore Pernagallo, C. W. Storck
Publikováno v:
Stem Cells Translational Medicine. 2:505-509
Faithfully recapitulating human physiology “in a dish” from a renewable source remains a holy grail for medicine and pharma. Many procedures have been described that, to a limited extent, exhibit human tissue-specific function in vitro. In partic
Publikováno v:
Bioanalysis. 2:1125-1140
Most therapeutic monoclonal antibodies are designed to bind a specific antigen to elicit pharmacological effects. Accurate quantification of a therapeutic monoclonal antibody in biological matrices is essential for assessing its pharmacokinetics and