Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Faye M. Walker"'
Autor:
Faye M. Walker, Lays Martin Sobral, Etienne Danis, Bridget Sanford, Sahiti Donthula, Ilango Balakrishnan, Dong Wang, Angela Pierce, Sana D. Karam, Soudabeh Kargar, Natalie J. Serkova, Nicholas K. Foreman, Sujatha Venkataraman, Robin Dowell, Rajeev Vibhakar, Nathan A. Dahl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Dynamic regulation of gene expression is fundamental for cellular adaptation to exogenous stressors. P-TEFb-mediated pause-release of RNA polymerase II (Pol II) is a conserved regulatory mechanism for synchronous transcriptional induction in
Externí odkaz:
https://doaj.org/article/d56159185f7f4564adf980120f3ab2ba
Autor:
Nathan A. Dahl, Etienne Danis, Ilango Balakrishnan, Dong Wang, Angela Pierce, Faye M. Walker, Ahmed Gilani, Natalie J. Serkova, Krishna Madhavan, Susan Fosmire, Adam L. Green, Nicholas K. Foreman, Sujatha Venkataraman, Rajeev Vibhakar
Publikováno v:
Cell Reports, Vol 31, Iss 1, Pp - (2020)
Summary: Histone 3 gene mutations are the eponymous drivers in diffuse midline gliomas (DMGs), aggressive pediatric brain cancers for which no curative therapy currently exists. These recurrent oncohistones induce a global loss of repressive H3K27me3
Externí odkaz:
https://doaj.org/article/658c8e9de95c4f8ea87a993cc17884db
Autor:
Faye M. Walker, Kuangwen Hsieh
Publikováno v:
Biosensors, Vol 9, Iss 4, p 117 (2019)
Advances in nucleic acid amplification technologies have revolutionized diagnostics for systemic, inherited, and infectious diseases. Current assays and platforms, however, often require lengthy experimental procedures and multiple instruments to rem
Externí odkaz:
https://doaj.org/article/14c672592c474f5d9009701591cdab1b
Autor:
Faye M. Walker, Lays Martin Sobral, Etienne Danis, Bridget Sanford, Ilango Balakrishnan, Dong Wang, Angela Pierce, Sana D. Karam, Natalie J. Serkova, Nicholas K. Foreman, Sujatha Venkataraman, Robin Dowell, Rajeev Vibhakar, Nathan A. Dahl
Publikováno v:
bioRxiv
Dynamic regulation of gene expression is fundamental for cellular adaptation to exogenous stressors. PTEFb-mediated pause-release of RNA polymerase II (Pol II) is a conserved regulatory mechanism for synchronous transcriptional induction in response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9133983a3a420710c3c9efbfe2987363
https://europepmc.org/articles/PMC9900817/
https://europepmc.org/articles/PMC9900817/
Autor:
Susan Fosmire, Rajeev Vibhakar, Senthilnath Lakshmana Chetty, Sujatha Venkataraman, Angela Pierce, Faye M. Walker, Nathan Dahl, Krishna Madhavan, Siddhartha Mitra, Ilango Balakrishnan
Publikováno v:
Neuro-Oncology. 23:i23-i23
Background and Rationale Diffuse intrinsic pontine glioma (DIPG) is one of the most aggressive pediatric brain tumors. Currently, the main treatment for DIPG is radiation and it’s only a palliative care, as the tumor eventually becomes resistant to
Autor:
Peter L. Mage, H. Tom Soh, Robert Strouse, James B. McGivney, Elizabeth R. Bagley, Michael Eisenstein, Faye M. Walker, Andrew T. Csordas, Margaret A. Nakamoto, Jose Casas-Finet, Christopher Larkin, Emily M. Gruber
Publikováno v:
Analytical chemistry. 90(5)
Biologic drugs are typically manufactured in mammalian host cells, and it is critical from a drug safety and efficacy perspective to detect and remove host cell proteins (HCPs) during production. This is currently achieved with sets of polyclonal ant
Publikováno v:
Analytical Chemistry
Molecular diagnostics based on the polymerase chain reaction (PCR) offer rapid and sensitive means for detecting infectious disease, but prohibitive costs have impeded their use in resource-limited settings where such diseases are endemic. In this wo
Autor:
James A. Thomson, Jamey D. Marth, Jeff Nie, H. Tom Soh, Ron Stewart, James Chambers, Minseon Cho, Seung Soo Oh, Michael Eisenstein, Faye M. Walker
Publikováno v:
Proceedings of the National Academy of Sciences. 110:18460-18465
Aptamers are promising affinity reagents that are potentially well suited for high-throughput discovery, as they are chemically synthesized and discovered via completely in vitro selection processes. Recent advancements in selection, sequencing, and
Design and self-assembly of siRNA-functionalized RNA nanoparticles for use in automated nanomedicine
Autor:
Wade W. Grabow, Marina A. Dobrovolskaia, Kirill A. Afonin, Faye M. Walker, Bruce A. Shapiro, Eckart Bindewald, Luc Jaeger
Individual genes can be targeted with siRNAs. The use of nucleic acid nanoparticles (NPs) is a convenient method for delivering combinations of specific siRNAs in an organized and programmable manner. We present three assembly protocols to produce tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d035865e8f78b8b31d18e41535f47d33
https://europepmc.org/articles/PMC3498981/
https://europepmc.org/articles/PMC3498981/
Publikováno v:
Journal of chemical ecology. 35(11)
Forked fungus beetles, Bolitotherus cornutus, feed, mate, and live on the brackets of several species of shelf fungus that grow on decaying logs. In response to the specific threat stimulus of mammalian breath, B. cornutus beetles produce a volatile