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pro vyhledávání: '"Faye A. Camp"'
Autor:
Faye A. Camp, Jill E. Slansky
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 993 (2021)
Many immunotherapies rely on CD8+ effector T cells to recognize and kill cognate tumor cells. These T cell-based immunotherapies include adoptive cell therapy, such as CAR T cells or transgenic TCR T cells, and anti-cancer vaccines which expand endog
Externí odkaz:
https://doaj.org/article/de33890daaff41279f0d1d7a0b3e6238
Autor:
Faye A, Camp, Tonya M, Brunetti, Michelle M, Williams, Jessica L, Christenson, Varsha, Sreekanth, James C, Costello, Zachary L Z, Hay, Ross M, Kedl, Jennifer K, Richer, Jill E, Slansky
Publikováno v:
Cancers. 14(18)
Antigenic differences formed by alterations in gene expression and alternative splicing are predicted in breast cancer cells undergoing epithelial to mesenchymal transition (EMT) and the reverse plasticity known as MET. How these antigenic difference
Publikováno v:
The Journal of Immunology. 208:121.04-121.04
Granzymes are a class of cytotoxic proteases and are the primary mechanism utilized by T cells to directly eliminate cancer cells. Each granzyme acts upon a unique set of substrates in target cells to induce cytotoxicity through a range of different
Autor:
Raul M. Torres, Peter M. Henson, Ross M. Kedl, Claudia Jakubzick, Sophie L. Gibbings, Elizabeth F. Redente, Faye A Camp, Shaikh M. Atif
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 59:580-591
Early recognition of neoantigen-expressing cells is complex, involving multiple immune cell types. In this study, in vivo, we examined how antigen-presenting cell subtypes coordinate and induce an immunological response against neoantigen-expressing