Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Faye, McLeod"'
Autor:
Faye McLeod, Elaine McDermott, Shermin Mak, Darren Walsh, Mark Turnbull, Fiona E. N. LeBeau, Andrew Jackson, Andrew J. Trevelyan, Gavin J. Clowry
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionExpression of light sensitive ion channels by selected neurons has been achieved by viral mediated transduction with gene constructs, but for this to have therapeutic uses, for instance in treating epilepsy, any adverse effects of viral i
Externí odkaz:
https://doaj.org/article/a562754520e34887bbc3e3de81c84cc0
Autor:
Nuria Martin Flores, Marina Podpolny, Faye McLeod, Isaac Workman, Karen Crawford, Dobril Ivanov, Ganna Leonenko, Valentina Escott-Price, Patricia C Salinas
Publikováno v:
eLife, Vol 12 (2024)
Increasing evidence supports a role for deficient Wnt signaling in Alzheimer’s disease (AD). Studies reveal that the secreted Wnt antagonist Dickkopf-3 (DKK3) colocalizes to amyloid plaques in AD patients. Here, we investigate the contribution of D
Externí odkaz:
https://doaj.org/article/7039ff22efa5466e8bf198b4a028d12c
Autor:
R. Ryley Parrish, Connie MacKenzie-Gray Scott, Tom Jackson-Taylor, Alex Grundmann, Faye McLeod, Neela K. Codadu, Alexandru Călin, Hannah Alfonsa, Rob C. Wykes, Juha Voipio, Andrew J. Trevelyan
Publikováno v:
The Journal of Neuroscience. 43:685-692
The movement of ions in and out of neurons can exert significant effects on neighboring cells. Here we report several experimentally important consequences of activation of the optogenetic chloride pump, halorhodopsin. We recorded extracellular K+con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::221d91b439c74cf82b768b7a54a6bf41
https://doi.org/10.1523/jneurosci.1141-22.2022
https://doi.org/10.1523/jneurosci.1141-22.2022
Autor:
Faye McLeod, Kieran Boyle, Aude Marzo, Nuria Martin-Flores, Thaw Zin Moe, Ernest Palomer, Alasdair J. Gibb, Patricia C. Salinas
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
Structural plasticity of synapses correlates with changes in synaptic strength. Dynamic modifications in dendritic spine number and size are crucial for long-term potentiation (LTP), the cellular correlate of learning and memory. Recent studies have
Externí odkaz:
https://doaj.org/article/5792d708508544b18729769bc036e430
Autor:
Faye McLeod, Alessandro Bossio, Aude Marzo, Lorenza Ciani, Sara Sibilla, Saad Hannan, Gemma A. Wilson, Ernest Palomer, Trevor G. Smart, Alasdair Gibb, Patricia C. Salinas
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1060-1071 (2018)
Summary: The structural and functional plasticity of synapses is critical for learning and memory. Long-term potentiation (LTP) induction promotes spine growth and AMPAR accumulation at excitatory synapses, leading to increased synaptic strength. Glu
Externí odkaz:
https://doaj.org/article/4a86144031c246239e56082deb8a5668
Autor:
Faye McLeod, Anna Dimtsi, Amy C Marshall, David Lewis-Smith, Rhys Thomas, Gavin J Clowry, Andrew J Trevelyan
Publikováno v:
Brain : a journal of neurology.
Early infantile developmental and epileptic encephalopathies are devastating conditions, generally of genetic origin, but the pathological mechanisms often remain obscure. A major obstacle in this field of research is the difficulty of studying corti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b073d755e2d364585b63d5b76fdf0f
https://pubmed.ncbi.nlm.nih.gov/36315647
https://pubmed.ncbi.nlm.nih.gov/36315647
Autor:
Nuria Martin-Flores, Marina Podpolny, Faye McLeod, Isaac Workman, Karen Crawford, Dobril Ivanov, Ganna Leonenko, Valentina Escott-Price, Patricia C. Salinas
Increasing evidence supports a role for deficient Wnt signaling in Alzheimer’s disease (AD). Studies reveal that the secreted Wnt antagonist Dickkopf-3 (DKK3) colocalizes to amyloid plaques in AD patients. Here, we investigate the contribution of D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3676aa18b0ede3be0e02798ff2bb27da
https://doi.org/10.1101/2022.06.16.495307
https://doi.org/10.1101/2022.06.16.495307
Autor:
Philip N. Dannhauser, Lisa Redlingshöfer, Marine D. Camus, Ernest Palomer, Frances M. Brodsky, Patricia C. Salinas, Faye McLeod, Kit Briant, Jemima J. Burden, Yu Chen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance This study reveals that diversity of clathrin light chain (CLC) subunits alters clathrin properties and demonstrates that the two neuronal CLC subunits work together for optimal clathrin function in synaptic vesicle formation. Our findin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5039d2093850975b3bc0c92d209b5b
https://doi.org/10.1073/pnas.2003662117
https://doi.org/10.1073/pnas.2003662117
Autor:
Faye McLeod, Rhys H. Thomas, Gavin J. Clowry, Anna Dimtsi, Andrew J. Trevelyan, David Lewis-Smith
Early infantile developmental and epileptic encephalopathies are devastating conditions, generally of genetic origin, but the pathological mechanisms often remain obscure. A major obstacle in this field of research is the difficulty of studying corti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efe11a4214dad736ec190f3a1967b0c6
https://doi.org/10.1101/2021.09.22.461333
https://doi.org/10.1101/2021.09.22.461333
Autor:
Kieran A. Boyle, Ernest Palomer, Alasdair J. Gibb, Nuria Martin-Flores, Patricia C. Salinas, Aude Marzo, Thaw Zin Moe, Faye McLeod
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
Structural plasticity of synapses correlates with changes in synaptic strength. Dynamic modifications in dendritic spine number and size are crucial for long-term potentiation (LTP), the cellular correlate of learning and memory. Recent studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63bc5270b60eceb8f8e56b359bdb702
https://doi.org/10.3389/fnsyn.2020.575863
https://doi.org/10.3389/fnsyn.2020.575863