Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Fayaz Malik"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-26 (2024)
Abstract Cancer treatment faces many hurdles and resistance is one among them. Anti-cancer treatment strategies are evolving due to innate and acquired resistance capacity, governed by genetic, epigenetic, proteomic, metabolic, or microenvironmental
Externí odkaz:
https://doaj.org/article/9d7fbf06779c4a2da350eb7763adea4c
Autor:
Sameer Ullah Khan, Anup Singh Pathania, Abubakar Wani, Kaneez Fatima, Mubashir Javed Mintoo, Baseerat Hamza, Masroor Ahmad Paddar, Wadhwa Bhumika, Loveleena Kour Anand, Mir Shahid Maqbool, Sameer Ahmad Mir, Jaspreet Kour, Vunnam Venkateswarlu, Dilip Manikrao Mondhe, Sanghapal D. Sawant, Fayaz Malik
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Lysosomal biogenesis plays a vital role in cell fate. Under certain conditions, excessive lysosomal biogenesis leads to susceptibility for lysosomal membrane permeabilization resulting in various pathological conditions including cell death.
Externí odkaz:
https://doaj.org/article/4068e835a7fa4caf83866b11c58f2661
Autor:
Sameer Ullah Khan, Anup Singh Pathania, Abubakar Wani, Kaneez Fatima, Mubashir Javed Mintoo, Baseerat Hamza, Masroor Ahmad Paddar, Wadhwa Bhumika, Loveleena Kour Anand, Mir Shahid Maqbool, Sameer Ahmad Mir, Jaspreet Kour, Vunnam Venkateswarlu, Dilip Manikrao Mondhe, Sanghapal D. Sawant, Fayaz Malik
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/ddcd6038d1364da4a39ebce350c045f7
Autor:
Suresh Kumar, Santosh Kumar Guru, Anup Singh Pathania, Nagaraju Mupparapu, Ajay Kumar, Fayaz Malik, Sandip B. Bharate, Qazi Naveed Ahmed, Ram A. Vishwakarma, Shashi Bhushan
Publikováno v:
Toxicology Reports, Vol 1, Iss C, Pp 1013-1025 (2014)
Crosstalk between apoptosis and autophagy is budding as one of the novel strategies in the cancer therapeutics. The present study tinted toward the interdependence of autophagy and apoptosis induce by a novel quinazolinone derivative 2,3-dihydro-2-(q
Externí odkaz:
https://doaj.org/article/a8c0d634550a4cc49254ffe08ab72d29
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148877 (2016)
Asparaginase is an important antileukemic agent extensively used worldwide but the intrinsic glutaminase activity of this enzymatic drug is responsible for serious life threatening side effects. Hence, glutaminase free asparaginase is much needed for
Externí odkaz:
https://doaj.org/article/011bb502bd1e4ec79714237aac5ae396
Autor:
Anup S Pathania, Suresh Kumar, Santosh K Guru, Shashi Bhushan, Parduman R Sharma, Sravan K Aithagani, Parvinder P Singh, Ram A Vishwakarma, Ajay Kumar, Fayaz Malik
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e110411 (2014)
Tryptanthrin is a natural product which has been reported to have several medicinal properties. In this study, we tried to investigate the detailed molecular mechanism of its bromo analogue (TBr), a potent cytotoxic agent in the induction of cancer c
Externí odkaz:
https://doaj.org/article/aa716eeb5bea49f49e02f8784e8dad20
Autor:
Neerupma Dhiman, Gazanfar Ahmad, Sameer Ullah Khan, Sameer Ahmad Mir, Mir Javid Iqbal, Faheem Hyder Pottoo, Fayaz Malik, Asif Ali
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 25:2372-2386
Myrica esculenta is an important ethnomedicinal plant used in the traditional system of medicine and as an important nutraceutical. Several studies on the plant justify its use in alternative systems of medicine and establish a scientific rationale f
Publikováno v:
Current Molecular Medicine. 23
Abstract: Natural remedies from a range of sources, including plants, animals, microorganisms, and marine life, have made a significant contribution to the treatment of many ailments. Lavender is a Mediterranean shrub from the Lamiaceae family. Laven
Publikováno v:
Clinical & Experimental Metastasis. 39:715-726
Anchorage-independent survival of cancer cells is associated with metastasis as it enables cells to travel to secondary target sites. Tissue integrity is generally maintained by detachment-induced cell death called 'anoikis', but cancer cells undergo
Autor:
Max S. Wicha, Hasan Korkaya, Daniel F. Hayes, Dafydd G. Thomas, Celina G. Kleer, Mark L. Day, Whitney A. Chadwick, Shawn G. Clouthier, Tahra K. Luther, Nader Tawakkol, Amber N. Heath, Nallasivam Palanisamy, Christopher L. Hall, April Davis, Stephanie Daignault, Kathleen Woods Ignatoski, Ahmed A. Quraishi, Tom F. Bersano-Begey, Scott J. Dawsey, Qin Zen, Fayaz Malik, Kathleen C. Day, Suthinee Ithimakin
PDF file - 491K, Supplementary Figure 3. Effect of trastazumab on stem cell marker expression. Supplementary Figure 2. Trastuzumab inhibits tertiary tumorsphere formation in luminal cell lines. Supplementary Figure 1. Representative FACS analysis dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560abdc1fd7d537096d1f2568089c598
https://doi.org/10.1158/0008-5472.22400423.v1
https://doi.org/10.1158/0008-5472.22400423.v1