Pharmacokinetics-Based Adjusted Versus Standard Dose of Ribavirin Does Not Improve Virologic Response Rates in Chronic Hepatitis C Genotype 4 Patients: A Randomized Controlled Trial

Autor: Mohammed A. Babatin, Abdulkareem M. Albekairy, Waleed Al-Tamimi, Sara I Altraif, Abduljaleel Alalwan, Musthafa Chalikandy Peedikayil, Khalid Alswat, Ayman A. Abdo, Mohammed Alquaiz, Waleed Al-Hamoudi, Mohammed A Alblawi, Shazia Murtaza, Fayaz A Handoo, Ibrahim Altraif, Abdulrahman Aljumah, Véronique Loustaud-Ratti, Faisal M. Sanai, Abdullah S. Alghamdi, Pierre Marquett, Fahad Alsohaibani, Hamad I. Al-Ashgar, Hamdan S. Alghamdi

Publikováno v: Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 37(11)

Optimal doses of Ribavirin (RBV) for hepatitis C virus (HCV) treatment are not known. To assess the safety and efficacy of PegIFNalfa-2a in combination with an adjusted (ADJ) RBV dose based on early pharmacokinetics versus a fixed standard (STD) dose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4402db3a97f78f63c93429b53272659a
https://pubmed.ncbi.nlm.nih.gov/29135370

Presentation, diagnosis and outcome of predominantly hepatic Wilson′s disease in adult Saudi patients: A single centre experience

Autor: Mohammed Al Jumah, Ibrahim Altraif, Abdulrahman Aljumah, Mohammed Afzal, Hamdan Al Ghamdi, Fayaz A. Handoo

Publikováno v: The Saudi Journal of Gastroenterology, Vol 18, Iss 5, Pp 334-338 (2012)
Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association

Background/Aim: To evaluate the clinical manifestations, diagnostic features, disease course and response to treatment among Saudi adults with predominantly hepatic Wilson's disease. A retrospective cohort study of 40 adult patients diagnosed with pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2fb2baa2fa59bcf6b492094f48303e
http://www.saudijgastro.com/article.asp?issn=1319-3767

HCV genotypes among 1013 Saudi nationals: a multicenter study

Autor: Ibrahim Al Traif, Mohammed A. Al Balwi, Ibrahim Abdulkarim, Fayaz A. Handoo, Hamdan Saleh Alqhamdi, Melfi Alotaibi, Abdulrahman Aljumah, Hamad Ibrahim Al Ashqar, Khalid Bzeizi, Mohammed Al Quaiz, Abduljaleel Alalwan, Waleed Al Hamoudi, Khalid Alswat, Faisal Sanai, Ayman Abdo

Publikováno v: Annals of Saudi Medicine, Vol 33, Iss 1, Pp 10-12 (2013)

BACKGROUND AND OBJECTIVES: Hepatitis C virus (HCV) genotype (G) knowledge is essential for determining type, duration and rate of response to antiviral therapy, possible route of HCV transmission, and future vaccine development. Our aim was to study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0cf3239563c432ffd0cad2e2cf9dd3a
https://pubmed.ncbi.nlm.nih.gov/23458933

Accuracy of International Guidelines for Identifying Significant Fibrosis in Hepatitis B e Antigen–Negative Patients With Chronic Hepatitis

Autor: Hamad Al Ashgar, Hamdan S. Alghamdi, Mohammed A. Babatin, Khaled O Alsaad, Hussa Al Hussaini, Robert P. Myers, Abdulrahman Aljumah, Waleed Al Hamoudi, Khalid I. Bzeizi, Abduljaleel Alalwan, Fayaz A. Handoo, Ayman A. Abdo, Fahad Alsohaibani, Faisal M. Sanai, Hadeel Al Mana, Abeer Ibrahim, Ibrahim Altraif

Publikováno v: Clinical Gastroenterology and Hepatology. 11:1493-1499.e2

Background & Aims Differing threshold levels of hepatitis B virus (HBV) DNA and alanine aminotransferase (ALT) are recommended by international guidelines for commencement of antiviral therapy. These guidelines advocate therapy for patients with sign

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c78307b26f52e91060b88c13ccad3c1
https://doi.org/10.1016/j.cgh.2013.05.038