Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Fayal Abderemane-Ali"'
Autor:
Olfat A. Malak, Fayal Abderemane-Ali, Yue Wei, Fabien C. Coyan, Gilyane Pontus, David Shaya, Céline Marionneau, Gildas Loussouarn
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract Prokaryotic NaV channels are tetramers and eukaryotic NaV channels consist of a single subunit containing four domains. Each monomer/domain contains six transmembrane segments (S1-S6), S1-S4 being the voltage-sensor domain and S5-S6 the pore
Externí odkaz:
https://doaj.org/article/c55713584dc441e5873be97cf8de9611
Autor:
Fabien C Coyan, Fayal Abderemane-Ali, Mohamed Yassine Amarouch, Julien Piron, Jérôme Mordel, Céline S Nicolas, Marja Steenman, Jean Mérot, Céline Marionneau, Annick Thomas, Robert Brasseur, Isabelle Baró, Gildas Loussouarn
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e93255 (2014)
INTRODUCTION:Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor necessary for the activity of KCNQ1 channels. Some Long QT mutations of KCNQ1, including R243H, R539W and R555C have been shown to decrease KCNQ1 interaction with PIP2. A previou
Externí odkaz:
https://doaj.org/article/2457806624d04ecea1b5be87c18b48d5
Autor:
Zhou Chen, Abhisek Mondal, Fayal Abderemane Ali, Seil Jang, Sangeeta Niranjan, José L. Montaño, Balyn W. Zaro, Daniel L. Minor
Publikováno v:
Nature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7138149dd786ac71bc16647ab5ac6d3d
https://doi.org/10.1038/s41586-023-06175-5
https://doi.org/10.1038/s41586-023-06175-5
Autor:
Zhou Chen, Sandra Zakrzewska, Holly S. Hajare, Aurora Alvarez-Buylla, Fayal Abderemane-Ali, Maximiliana Bogan, Dave Ramirez, Lauren A. O’Connell, J. Du Bois, Daniel L. Minor
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 44
American bullfrog ( Rana castesbeiana ) saxiphilin ( Rc Sxph) is a high-affinity “toxin sponge” protein thought to prevent intoxication by saxitoxin (STX), a lethal bis-guanidinium neurotoxin that causes paralytic shellfish poisoning (PSP) by blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025c106450d858e7d469c2c41b558667
https://pubmed.ncbi.nlm.nih.gov/36279441
https://pubmed.ncbi.nlm.nih.gov/36279441
Voltage-gated ion channels (VGICs) comprise multiple structural units whose assembly is required for function1,2. There is scant structural understanding of how VGIC subunits assemble and whether chaperone proteins are required. High-voltage activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5351e8acc6f96dd7a448b67413635499
https://doi.org/10.1101/2022.10.03.510667
https://doi.org/10.1101/2022.10.03.510667
Autor:
Justin Du Bois, Fayal Abderemane-Ali, Tim M. G. MacKenzie, Daniel L. Minor, CatherineE. Garrison
Publikováno v:
Cell Chem Biol
Cell chemical biology, vol 29, iss 4
Cell chemical biology, vol 29, iss 4
Voltage-gated sodium channels (NaVs), large transmembrane protein complexes responsible for the initiation and propagation of action potentials, are targets for a number of acute poisons. Many of these agents act as allosteric modulators of channel a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ea857e42ff258b63547462850aa1b8
https://pubmed.ncbi.nlm.nih.gov/34963066
https://pubmed.ncbi.nlm.nih.gov/34963066
Autor:
Claire M. Colleran, Robert A. Craig, Catherine E. Garrison, Megan E. Kobiela, Zhou Chen, John P. Dumbacher, Lauren A. O’Connell, Fayal Abderemane-Ali, Daniel L. Minor, Nathan D. Rossen, J. Du Bois
Publikováno v:
The Journal of general physiology, vol 153, iss 9
The Journal of General Physiology
The Journal of General Physiology
Some poisonous animals produce toxins that affect Na+ channel function yet avoid autointoxication. Abderemane-Ali et al. show that resistance by Pitohui birds and Phyllobates frogs to their own toxins may be mediated not by mutations in their channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8851458c1711bcba644a3cefa40512
https://pubmed.ncbi.nlm.nih.gov/34491263
https://pubmed.ncbi.nlm.nih.gov/34491263
Autor:
Megan E. Kobiela, Nathan D. Rossen, Robert A. Craig, John P. Dumbacher, Catherine E. Garrison, Lauren A. O’Connell, J. Du Bois, Fayal Abderemane-Ali, Daniel L. Minor
Poisonous organisms carry small molecule toxins that alter voltage-gated sodium channel (Na✓) function. Among these, batrachotoxin (BTX) fromPitohuitoxic birds andPhyllobatespoison frogs, stands out because of its lethality and unusual effects on N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17a82f7af96a94cb21e083854fcfc90f
https://doi.org/10.1101/2020.10.29.361212
https://doi.org/10.1101/2020.10.29.361212
Autor:
Andrew M. Natale, Daniel L. Minor, Michael Grabe, Armin Wagner, Sara Capponi, Fayal Abderemane-Ali, David Crottès, Ramona Duman, John M. Rosenberg, Marco Lolicato
Publikováno v:
Science advances, vol 6, iss 44
Science Advances
BIOPHYSICAL JOURNAL, vol 120, iss 3
Science Advances
BIOPHYSICAL JOURNAL, vol 120, iss 3
The innately heterodimeric K2P filter permits two C-type gating mechanisms, pinching and dilation, to operate in one channel.
K2P potassium channels regulate cellular excitability using their selectivity filter (C-type) gate. C-type gating mecha
K2P potassium channels regulate cellular excitability using their selectivity filter (C-type) gate. C-type gating mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03bc4ef1b98d5e3e911c739a2c83c76
https://escholarship.org/uc/item/5x58t3bj
https://escholarship.org/uc/item/5x58t3bj
Autor:
Sara Capponi, Daniel L. Minor, Armin Wagner, David Crottès, John M. Rosenberg, Andrew M. Natale, Fayal Abderemane-Ali, Ramona Duman, Marco Lolicato, Michael Grabe
Publikováno v:
Biophysical Journal, vol 120, iss 3
Author(s): Natale, Andrew M; Lolicato, Marco Gaetano Lorenz; Abderemane-Ali, Fayal; Crottes, David; Capponi, Sara; Duman, Ramona; Wagner, Armin; Rosenberg, John M; Grabe, Michael; Minor, Daniel L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457f8b3ef2333e3ceb02d2c07476ffea
https://doi.org/10.1016/j.bpj.2020.11.898
https://doi.org/10.1016/j.bpj.2020.11.898