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pro vyhledávání: '"Fay W. Ng"'
Autor:
Joy A. Middleton, Robert Downham, Neil K. Garg, Sheldon Hiebert, Michael Becker, Peter Chua, Larry E. Overman, Fay W. Ng, Stefan Jaroch, Richard T. Matsuoka, Christopher J. Douglas
Publikováno v:
Journal of the American Chemical Society. 129:11987-12002
This article describes the details of our synthetic studies toward the complex marine alkaloid sarain A. Various strategies were conceived, setbacks encountered, and solutions developed, ultimately leading to a successful enantioselective total synth
Publikováno v:
Journal of the American Chemical Society. 124:9812-9824
The total synthesis of (+/-)-gelsemine (1) is described. A defining phase of the effort involved recourse to a strategic oxetane ring (see compound 25). It was constructed anticipating an intramolecular displacement of the carbon (C17)-oxygen (O4) bo