Zobrazeno 1 - 10
of 20 279
pro vyhledávání: '"Fay P"'
Autor:
Rebecca Clarke, Tehmina Bharucha, Benediktus Yohan Arman, Bevin Gangadharan, Laura Gomez Fernandez, Sara Mosca, Qianqi Lin, Kerlijn Van Assche, Robert Stokes, Susanna Dunachie, Michael Deats, Hamid A. Merchant, Céline Caillet, John Walsby-Tickle, Fay Probert, Pavel Matousek, Paul N. Newton, Nicole Zitzmann, James S. O. McCullagh
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract The global population is increasingly reliant on vaccines to maintain population health with billions of doses used annually in immunisation programmes. Substandard and falsified vaccines are becoming more prevalent, caused by both the degra
Externí odkaz:
https://doaj.org/article/f005fcfa3a62421b8cb44d66f94b298d
Autor:
Wenzheng Xiong, Tianrong Yeo, Jeanne Tan May May, Tor Demmers, Bryan Ceronie, Archana Ramesh, Ronan N. McGinty, Sophia Michael, Emma Torzillo, Arjune Sen, Daniel C. Anthony, Sarosh R. Irani, Fay Probert
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 7, Pp 1897-1908 (2024)
Abstract Objective Differentiating forms of autoimmune encephalitis (AE) from other causes of seizures helps expedite immunotherapies in AE patients and informs studies regarding their contrasting pathophysiology. We aimed to investigate whether and
Externí odkaz:
https://doaj.org/article/13a7e791520744c9a48b04847a9c04de
Publikováno v:
Metabolites, Vol 14, Iss 11, p 609 (2024)
Background/Objectives: Metabolic profiling of tissue samples via liquid-state nuclear magnetic resonance (NMR) requires the extraction of polar metabolites in a suitable deuterated solvent. Such methods often prioritise metabolite recovery over prote
Externí odkaz:
https://doaj.org/article/2d445c4047464f7eaa8ae8423983b878
Autor:
Daniel C. Anthony, Fay Probert, Anna Gorlova, Jenna Hebert, Daniel Radford-Smith, Zlata Nefedova, Aleksei Umriukhin, Andrey Nedorubov, Raymond Cespuglio, Boris Shulgin, Aleksey Lyundup, Klaus Peter Lesch, Tatyana Strekalova
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 884 (2024)
The impaired function of the serotonin transporter (SERT) in humans has been linked to a higher risk of obesity and type 2 diabetes, especially as people age. Consuming a “Western diet” (WD), which is high in saturated fats, cholesterol, and suga
Externí odkaz:
https://doaj.org/article/2b9262aba5ef4959863634dd07723836
Autor:
Isobel K. Dunstan, Ross McLeod, Daniel E. Radford-Smith, Wenzheng Xiong, Trinity Pate, Fay Probert, Daniel C. Anthony
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
IntroductionPost-infection syndromes are characterised by fatigue, muscle pain, anhedonia, and cognitive impairment; mechanistic studies exploring these syndromes have focussed on pathways downstream of Toll-like receptor (TLR) 4 activation. Here, we
Externí odkaz:
https://doaj.org/article/9244bad03f17430d921628b23178d2c0
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Endotoxemia and sepsis induce neuroinflammation and increase the risk of neurodegenerative disorders although the mechanism by which peripheral infection leads to brain inflammation is not well understood. While circulating serum lipoprotein
Externí odkaz:
https://doaj.org/article/a0ae16dbb7b5460b94d403c920a6f699
Autor:
Tianrong Yeo, Halwan Bayuangga, Marcus Augusto-Oliveira, Megan Sealey, Timothy D. W. Claridge, Rachel Tanner, David Leppert, Jacqueline Palace, Jens Kuhle, Fay Probert, Daniel C. Anthony
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Despite widespread searches, there are currently no validated biofluid markers for the detection of subclinical neuroinflammation in multiple sclerosis (MS). The dynamic nature of human metabolism in response to changes in homeost
Externí odkaz:
https://doaj.org/article/ed702fcc50c7445ca41523389ff78f61
Autor:
Daniel E. Radford-Smith, Daniel C. Anthony, Fee Benz, James T. Grist, Monty Lyman, Jack J. Miller, Fay Probert
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104643- (2023)
Summary: Background: Socioeconomic pressures, sex, and physical health status strongly influence the development of major depressive disorder (MDD) and mask other contributing factors in small cohorts. Resilient individuals overcome adversity without
Externí odkaz:
https://doaj.org/article/1fac2c44da6f4607b1a375839a2c23ff
Autor:
Kathryn R Martin, Annina B Schmid, Brigitte Tampin, Marco Barbero, Christine Price, Louise Hailey, Claire Robinson, Jeremy Fairbank, Geert Crombez, Georgios Baskozos, Daniel Nanz, Sarim Ather, Lucy Ridgway, Mohamed Tachrount, Fay Probert, Whitney Scott, Soraya Koushesh, Stuart Clare
Publikováno v:
BMJ Open, Vol 13, Iss 4 (2023)
Introduction Sciatica is a common condition and is associated with higher levels of pain, disability, poorer quality of life, and increased use of health resources compared with low back pain alone. Although many patients recover, a third develop per
Externí odkaz:
https://doaj.org/article/c252c602d0884ff896f648bbb2a1b5b2
We introduce a locally differentially private (LDP) algorithm for online federated learning that employs temporally correlated noise to improve utility while preserving privacy. To address challenges posed by the correlated noise and local updates wi
Externí odkaz:
http://arxiv.org/abs/2411.18752
