Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Fay Ashby"'
Autor:
Harriet S. Walter, Victoria Coyle, J.S. de Bono, A. Hughes, William H. West, T. Knurowski, Nigel Brooks, Fay Ashby, Simon Pacey, Neil Anthony Pegg, Louise Carter, Simon J. Crabb, Alastair Greystoke, Ruth Plummer, Karen Clegg
Publikováno v:
Annals of Oncology. 32:S617
Autor:
Harriet S. Walter, Tim C. P. Somervaille, Andrew Davies, William H. West, Nigel Brooks, Fay Ashby, Karen Clegg, Tomasz Knurowski, Neil Anthony Pegg, Steven Knapper
Publikováno v:
Blood. 134:1266-1266
Background CCS1477 is a first in class potent, selective and orally bioavailable inhibitor of the bromodomains of p300 and CBP, two closely related histone acetyl transferases with oncogenic roles in haematological malignancies. In pre-clinical studi
Autor:
Elena Cojocaru, Johann S. de Bono, Karen Clegg, Tomasz Knurowski, William H. West, Fay Ashby, Anthony Nigel Brooks, Neil Anthony Pegg, Elizabeth Ruth Plummer
Publikováno v:
Journal of Clinical Oncology. 37:TPS5089-TPS5089
TPS5089 Background: CCS1477 is a potent, selective and orally bioavailable inhibitor of the bromodomain of p300 and CBP, two homologous and critical co-activators of the androgen receptor (AR) and its variant forms, including mutated, amplified and s