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3-Alkenyl-2-oxindoles: Synthesis, antiproliferative and antiviral properties against SARS-CoV-2.

Autor: Girgis AS; Department of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, Egypt. Electronic address: girgisas10@yahoo.com., Panda SS; Department of Chemistry & Physics, Augusta University, Augusta, GA 30912, USA., Srour AM; Department of Therapeutic Chemistry, National Research Centre, Dokki, Giza 12622, Egypt., Abdelnaser A; Institute of Global Health and Human Ecology, School of Sciences and Engineering, The American University in Cairo (AUC), Cairo 11835, Egypt., Nasr S; Institute of Global Health and Human Ecology, School of Sciences and Engineering, The American University in Cairo (AUC), Cairo 11835, Egypt; Institute of Pharmacology of Natural Products & Clinical Pharmacology, Ulm University, D-89081 Ulm, Germany., Moatasim Y; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt., Kutkat O; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt., El Taweel A; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt., Kandeil A; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt., Mostafa A; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt., Ali MA; Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt., Fawzy NG; Department of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, Egypt., Bekheit MS; Department of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, Egypt., Shalaby EM; X-Ray Crystallography Lab., Physics Division, National Research Centre, Dokki, Giza 12622, Egypt., Gigli L; Elettra-Sincrotrone Trieste, s.s. 14 Km 163.5 in Area Science Park, Basovizza (Trieste) 34149, Trieste, Italy., Fayad W; Drug Bioassay-Cell Culture Laboratory, Pharmacognosy Department, National Research Centre, Dokki, Giza, 12622. Egypt., Soliman AAF; Drug Bioassay-Cell Culture Laboratory, Pharmacognosy Department, National Research Centre, Dokki, Giza, 12622. Egypt.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2021 Sep; Vol. 114, pp. 105131. Date of Electronic Publication: 2021 Jun 30.

Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone-dichloroacetic acid hybrids.

Autor: Seliem IA; Department of Chemistry and Physics, Augusta University, Augusta, GA, USA.; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt., Panda SS; Department of Chemistry and Physics, Augusta University, Augusta, GA, USA., Girgis AS; Department of Pesticide Chemistry, National Research Centre, Giza, Egypt., Nagy YI; Microbiology and Immunology Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt., George RF; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Fayad W; Drug Bioassay-Cell Culture Laboratory, Pharmacognosy Department, National Research Centre, Giza, Egypt., Fawzy NG; Department of Pesticide Chemistry, National Research Centre, Giza, Egypt., Ibrahim TS; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia., Al-Mahmoudy AMM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt., Sakhuja R; Department of Chemistry, Birla Institute of Technology and Science, Pilani, India., Abdel-Samii ZKM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.

Publikováno v: Chemical biology & drug design [Chem Biol Drug Des] 2020 Feb; Vol. 95 (2), pp. 248-259. Date of Electronic Publication: 2019 Nov 02.

Facile synthetic approach towards vasorelaxant active 4-hydroxyquinazoline-4-carboxamides.

Autor: Aziz MN; Department of Pesticide Chemistry, National Research Centre Dokki Giza 12622 Egypt girgisas10@yahoo.com., Panda SS; Department of Chemistry & Physics, Augusta University Augusta GA 30912 USA., Shalaby EM; X-Ray Crystallography Lab, Physics Division, National Research Centre Dokki Giza 12622 Egypt., Fawzy NG; Department of Pesticide Chemistry, National Research Centre Dokki Giza 12622 Egypt girgisas10@yahoo.com., Girgis AS; Department of Pesticide Chemistry, National Research Centre Dokki Giza 12622 Egypt girgisas10@yahoo.com.

Publikováno v: RSC advances [RSC Adv] 2019 Sep 10; Vol. 9 (49), pp. 28534-28540. Date of Electronic Publication: 2019 Sep 10 (Print Publication: 2019).

Novel Curcumin Inspired Antineoplastic 1-Sulfonyl-4-Piperidones: Design, Synthesis and Molecular Modeling Studies.

Autor: Fawzy NG; Department of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, Egypt., Panda SS; Department of Chemistry & Physics, Augusta University, Augusta, GA 30912, United States., Fayad W; Drug Bioassay-Cell Culture Laboratory, Pharmacognosy Department, National Research Centre, Dokki, Giza, 12622, Egypt., El-Manawaty MA; Drug Bioassay-Cell Culture Laboratory, Pharmacognosy Department, National Research Centre, Dokki, Giza, 12622, Egypt., Srour AM; Department of Therapeutic Chemistry, National Research Centre, Dokki, Giza 12622, Egypt., Girgis AS; Department of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, Egypt.

Publikováno v: Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2019; Vol. 19 (8), pp. 1069-1078.