Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Fawzi Babiker"'
Publikováno v:
Biomolecules & Biomedicine (2024)
Polyamidoamine (PAMAM) dendrimer nanoparticles are efficient drug delivery vectors with potential clinical applications in nanomedicine. However, PAMAMs can compromise heart function, and strategies to mitigate cardiotoxicity would be beneficial. In
Externí odkaz:
https://doaj.org/article/cf8b209133af4636a144937844f334d2
Autor:
Eman Gouda, Fawzi Babiker
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Gum Arabic (GA) is a plant exudate with antioxidant and anti-inflammatory effects. GA has shown promise in protection from and treatment of kidney failure, however, its role in the protection of the heart from ischemia and reperfusion (I/R)
Externí odkaz:
https://doaj.org/article/dc337fc815144dcb81e4c4c3ae95c59b
Publikováno v:
Pharmaceuticals, Vol 16, Iss 4, p 492 (2023)
Ischemia and perfusion (I/R) induce inflammation and oxidative stress, which play a notable role in tissue damage. The aim of this study was to investigate the role of an NADPH oxidase inhibitor (apocynin) in the protection of the heart from I/R inju
Externí odkaz:
https://doaj.org/article/d3d5773e6247442a80594ab948bacbaf
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 238 (2023)
Background: Diabetes mellitus (DM) is a risk factor for cardiovascular diseases, specifically, the ischemic heart diseases (IHD). The renin–angiotensin system (RAS) affects the heart directly and indirectly. However, its role in the protection of t
Externí odkaz:
https://doaj.org/article/45a8e0826c084aae975deb0115ba625c
Autor:
Aishah Al-Jarallah, Fawzi Babiker
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundHypertension is a key risk factor in the development of cardiovascular diseases. Elevation in blood pressure alters high density lipoprotein (HDL) function and composition. The exact role of HDL in cardiovascular complications observed in h
Externí odkaz:
https://doaj.org/article/a82bc7896b114e37862464917e20de1a
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2673 (2022)
Aim: The influence of the physiochemical properties of dendrimer nanoparticles on cardiac contractility and hemodynamics are not known. Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and
Externí odkaz:
https://doaj.org/article/1f2a02fdaf934c4488a76f46e058fa4f
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 720 (2022)
Tirzepatide is a dual glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist and a promising therapy for type 2 diabetes mellitus (T2DM). GLP-1 is an incretin hormone with therapeutic potential beyond
Externí odkaz:
https://doaj.org/article/d21596c36ba5426eabbbdb52ec41f792
Autor:
Elham Ghadhanfar, Aseel Alsalem, Shaimaa Al-Kandari, Jumana Naser, Fawzi Babiker, Maie Al-Bader
Publikováno v:
Reproductive Biology and Endocrinology, Vol 15, Iss 1, Pp 1-9 (2017)
Abstract Background Plasma and urine levels of the potent vasodilator Ang-(1–7) are elevated in mid and late pregnancy and are correlated with elevated placental angiogenesis, fetal blood flow, and rapid fetal growth. We hypothesized that Ang-(1–
Externí odkaz:
https://doaj.org/article/d30a4f5fc3db41769bdb816a383516b9
Autor:
Waleed Al-Herz, Fawzi Babiker
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 6, Pp 2295-2306 (2017)
Background/Aims: To investigate the cardioprotective effects of intravenous immunoglobulins (IVIG) in rats subjected to regional myocardial ischemia reperfusion (I/R). Methods: Langendorff-perfused rat hearts were used in this study. Hearts subjected
Externí odkaz:
https://doaj.org/article/3641d3ac024d4761bb9567545f43751c
Publikováno v:
Cardiology Research and Practice, Vol 2019 (2019)
Background. Aging, left ventricular hypertrophy (LVH), diabetes mellitus, and pregnancy are well-recognized risk factors that increase the prevalence of cardio-ischemic events and are linked to poor clinical recovery following acute myocardial infarc
Externí odkaz:
https://doaj.org/article/ad855df548a5465ca8b7a0c9c75191b8