Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Fawnda, Pellett"'
Autor:
Jeffrey A. Berinstein, Vinod Chandran, Fawnda Pellett, Arane Thavaneswaran, Remy A. Pollock, Dafna D. Gladman
Publikováno v:
Clinical Rheumatology. 36:2261-2266
The purpose of this study is to examine the genetic interaction of variably expressed killer cell immunoglobulin-like receptor (KIR) 3DL1 alleles with their cognate ligand, human leukocyte antigen (HLA)-Bw4, in susceptibility to psoriatic disease (Ps
Autor:
Zahi Touma, Vinod Chandran, Fawnda Pellett, Arane Thavaneswaran, Dafna D. Gladman, Richard J. Cook
Publikováno v:
The Journal of Rheumatology. 43:1057-1062
Objective.Psoriatic arthritis (PsA) has been recognized as a severe erosive disease. However, some patients do not develop erosions. We aimed to determine the prevalence, characteristics, and predictors of erosion-free patients (EFP) as compared with
Autor:
Arane Thavaneswaran, Art Petronis, Remy A. Pollock, Dafna D. Gladman, Proton Rahman, Vinod Chandran, Fawnda Pellett
Publikováno v:
Arthritis Care & Research. 67:1586-1590
Objective To further explore the “parent-of-origin” effect in a large cohort of well-phenotyped patients with cutaneous psoriasis without arthritis (PsC) and psoriatic arthritis (PsA). Methods Self-reported family history was obtained from PsA pa
Autor:
Vinod Chandran, Fawnda Pellett, Dafna D. Gladman, Amir Haddad, Ioana Ruiz-Arruza, Arane Thavaneswaran, Richard J. Cook
Publikováno v:
Arthritis Care & Research. 67:842-847
Objective A state of minimal disease activity (MDA) was defined and validated as target for treatment in psoriatic arthritis (PsA). We aimed to identify disease characteristics, outcome, and predictors of MDA in patients treated with tumor necrosis f
Autor:
Carl Virtanen, Remy A. Pollock, Kun Liang, Vinod Chandran, Fawnda Pellett, Fatima Abji, Dafna D. Gladman
Publikováno v:
Journal of Investigative Dermatology. 135:620-623
Autor:
Arane Thavaneswaran, Dafna D. Gladman, Joan E. Wither, Vinod Chandran, Fawnda Pellett, Amir Haddad, Fatima Abji
Publikováno v:
The Journal of Rheumatology. 41:2421-2424
Objective.The occurrence of monoclonal gammopathy of undetermined significance (MGUS) is common in chronic immune mediated disorders. This increased monoclonal antibody production could result from chronic stimulation of lymphocytes, with the immunog
Autor:
Michael Weichenthal, Soumya Raychaudhuri, Anne M. Bowcock, Yukinori Okada, Peter K. Gregersen, Trilokraj Tejasvi, Philip E. Stuart, John J. Voorhees, Andre Franke, Vinod Chandran, Fawnda Pellett, Dafna D. Gladman, James T. Elder, Lam C. Tsoi, Proton Rahman, Paul I.W. de Bakker, Eva Ellinghaus, Buhm Han, Gonçalo R. Abecasis, Remy A. Pollock, Rajan P. Nair, Gerald G. Krueger
Publikováno v:
The American Journal of Human Genetics. 95:162-172
Psoriasis vulgaris (PsV) risk is strongly associated with variation within the major histocompatibility complex (MHC) region, but its genetic architecture has yet to be fully elucidated. Here, we conducted a large-scale fine-mapping study of PsV risk
Autor:
Richard J. Cook, Vinod Chandran, Fawnda Pellett, Dafna D. Gladman, Adele Carty, Hua Shen, Remy A. Pollock
Publikováno v:
The Journal of Rheumatology. 40:866-871
Objective.To identify soluble biomarkers associated with response to therapy with tumor necrosis factor inhibitors (TNFi) in patients with psoriatic arthritis (PsA).Methods.The study was conducted at a PsA clinic where patients are assessed every 6 m
Autor:
Vernon T. Farewell, Dafna D. Gladman, Proton Rahman, Arane Thavaneswaran, Jessica K. Barrett, Vinod Chandran, Fawnda Pellett, Lihi Eder, Remy A. Pollock
Publikováno v:
Tissue Antigens. 82:43-47
A methionine/valine polymorphism at amino acid 129 of the major histocompatibility complex class I chain-related gene A (MICA-129) categorizes alleles into strong and weak binders of the natural killer (NK) and T-cell receptor NKG2D. We investigated
Autor:
Cheryl F. Rosen, Jai Jayakar, Lihi Eder, Dafna D. Gladman, Vinod Chandran, Fawnda Pellett, Arane Thavaneswaran, Remy A. Pollock
Publikováno v:
Annals of the Rheumatic Diseases. 72:1956-1961
ObjectiveTo compare the prevalence of metabolic syndrome (MetS) and the levels of related biomarkers in patients with psoriatic arthritis (PsA) and psoriasis without arthritis (PsC).MethodsThis study compared patients with PsA and patients with PsC.