Zobrazeno 1 - 10
of 397
pro vyhledávání: '"Fawcett JW"'
Autor:
Fawcett, JW, Kwok, JCF
Chondroitin sulphate and heparan sulphate proteoglycans (CSPGS and HSPGs) are found throughout the central nervous system (CNS). CSPGs are ubiquitous in the diffuse extracellular matrix (ECM) between cells and are a major component of perineuronal ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::28e5418f62d9ac96753577f19f5fa2c1
Autor:
Vennin, C, Melenec, P, Rouet, R, Nobis, M, Cazet, As, Murphy, Kj, Herrmann, D, Reed, Da, Lucas, Mc, Warren, Sc, Elgundi, Z, Pinese, M, Kalna, G, Roden, D, Samuel, M, Zaratzian, A, Grey, St, Da Silva, A, Leung, W, Mathivanan, S, Wang, Yx, Braithwaite, Aw, Christ, D, Benda, A, Parkin, A, Phillips, Pa, Whitelock, Jm, Gill, Aj, Sansom, Oj, Croucher, Dr, Parker, Bl, Pajic, M, Morton, Jp, Cox, Tr, Timpson, P, Johns, Al, Chantrill, La, Chou, A, Steinmann, A, Arshi, M, Dwarte, T, Froio, D, Pereira, B, Ritchie, S, Chambers, Cr, Metcalf, X, Waddell, N, Pearson, Jv, Patch, Am, Nones, K, Newell, F, Mukhopadhyay, P, Addala, V, Kazakoff, S, Holmes, O, Leonard, C, Wood, S, Grimmond, Sm, Hofmann, O, Christ, A, Bruxner, T, Samra, Js, Pavlakis, N, High, Ha, Asghari, R, Merrett, Nd, Pavey, D, Das, A, Cosman, Ph, Ismail, K, O'Connnor, C, Stoita, A, Williams, D, Spigellman, A, Lam, Vw, Mcleod, D, Kirk, J, Kench, Jg, Grimison, P, Cooper, Cl, Sandroussi, C, Goodwin, A, Mead, Rs, Tucker, K, Andrews, L, Texler, M, Forest, C, Epari, Kp, Ballal, M, Fletcher, Dr, Mukhedkar, S, Zeps, N, Beilin, M, Feeney, K, Nguyen, Nq, Ruszkiewicz, Ar, Worthley, C, Chen, J, Brooke-Smith, Me, Papangelis, V, Clouston, Ad, Barbour, Ap, O'Rourke, Tj, Fawcett, Jw, Slater, K, Hatzifotis, M, Hodgkinson, P, Nikfarjam, M, Eshleman, Jr, Hruban, Rh, Wolfgang, Cl, Lawlor, Rt, Beghelli, S, Corbo, V, Scardoni, M, Bassi, C, Biankin, Av, Dixon, J, Jamieson, Nb, Chang, Dk
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-22 (2019)
Nature Communications
Nature Communications
Heterogeneous subtypes of cancer-associated fibroblasts (CAFs) coexist within pancreatic cancer tissues and can both promote and restrain disease progression. Here, we interrogate how cancer cells harboring distinct alterations in p53 manipulate CAFs
Regeneration after spinal cord injury is a goal of many studies. Although the most obvious target is to recover motor function, restoration of sensation can also improve the quality of life after spinal cord injury. For many patients, recovery of sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::3d1a05d5df84845bb122e55eaab9ca5a
Autor:
Kempf, A, Boda, E, Kwok, JCF, Fritz, R, Grande, V, Kaelin, AM, Ristic, Z, Schmandke, A, Tews, B, Fawcett, JW, Pertz, O, Buffo, A, Schwab, ME
Heparan sulfate proteoglycans (HSPGs) critically modulate adhesion-, growth- and migration related processes. Here we show that the transmembrane protein Nogo-A inhibits neurite outgrowth and cell spreading in neurons and Nogo-A-responsive cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::4ac6cb9911b7f4a037bd93bc8b0dab99
Autor:
Yang S, Cacquevel M, Saksida L, Bussey T, Schneider, B, Aebischer, P, Melani, Riccardo, Pizzorusso, Tommaso, Fawcett, Jw
Alzheimer's disease is the most prevalent tauopathy and cause of dementia. We investigate the hypothesis that reactivation of plasticity can restore function in the presence of neuronal damage resulting from tauopathy. We investigated two models with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2fe9d655780e6da4927f166a7799d618
http://www.scopus.com/inward/record.url?eid=2-s2.0-84921445315&partnerID=40&md5=6410f3e951d67bc33e66573e456bdf46
http://www.scopus.com/inward/record.url?eid=2-s2.0-84921445315&partnerID=40&md5=6410f3e951d67bc33e66573e456bdf46
Autor:
Tyzack, GE, Sitnikov, S, Barson, D, Adams-Carr, KL, Lau, NK, Kwok, JC, Zhao, C, Franklin, RJM, Karadottir, RT, Fawcett, JW, Lakatos, A
Publikováno v:
Nature Communications
The role of remote astrocyte (AC) reaction to central or peripheral axonal insult is not clearly understood. Here we use a transgenic approach to compare the direct influence of normal with diminished AC reactivity on neuronal integrity and synapse r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b6d8b7329ac3685dd95e50b1090158e5
https://www.repository.cam.ac.uk/handle/1810/245879
https://www.repository.cam.ac.uk/handle/1810/245879
Autor:
Tactacan, Carole M, Chang, David K, Cowley, Mark J, Humphrey, Emily S, Jianmin, Wu, Gill, Anthony J, Chou, Angela, Nones, Katia, Grimmond, Sean M, Sutherland, Robert L, Biankin, Andrew V, Daly, Roger J, Biankin, Av, Johns, Al, Mawson, A, Chang, Dk, Scarlett, Cj, Brancato, Ma, Rowe, Sj, Simpson, Sl, Martyn-Smith, M, Chantrill, La, Chin, Vt, Chou, A, Cowley, Mj, Caplan, W, Humphris, Jl, Jones, Md, Mead, R, Nagrial, Am, Pajic, M, Pettit, J, Pinese, M, Rooman, I, Wu, Jun, Daly, Rj, Musgrove, Ea, Sutherland, Rl, Grimmond, Sm, Waddell, N, Kassahn, Ks, Miller, Dk, Wilson, Pj, Patch, Am, Song, S, Harliwong, I, Idrisoglu, S, Nourse, C, Nourbakhsh, E, Manning, S, Wani, S, Gongora, M, Anderson, Michela, Holmes, O, Leonard, C, Taylor, D, Wood, JOHN STEPHAN, Xu, C, Nones, K, Fink, Julika, Christ, A, Bruxner, T, Cloonan, N, Newell, F, Pearson, Jv, Samra, Js, Gill, Aj, Nickpavlakis, Guminski, A, Toon, C, Asghari, R, Merrett, Nd, Pavey, Da, Das, A, Cosman, Ph, Ismail, K, O'Connor, C, Lam, Vw, Mcleod, D, Pleass, Hc, James, V, Kench, Jg, Cooper, Cl, Joseph, D, Sandroussi, C, Crawford, M, Texler, M, Forrest, C, Laycock, A, Epari, Kp, Ballal, M, Fletcher, Dr, Mukhedkar, S, Spry, Na, Deboer, B, Chai, M, Feeney, K, Zeps, N, Beilin, M, Nguyen, Nq, Ruszkiewicz, Ar, Worthley, C, Tan, Cp, Debrencini, T, Chen, J, Brooke-Smith, Me, Papangelis, V, Tang, H, Barbour, Ap, Clouston, Ad, Martin, P, O'Rourke, Tj, Chiang, A, Fawcett, Jw, Slater, K, Yeung, S, Hatzifotis, M, Hodgkinson, P, Christophi, C, Nikfarjam, M, Eshleman, Jr, Hruban, Rh, Maitra, A, Iacobuzio-Donahue, Ca, Schulick, Rd, Wolfgang, Cl, Morgan, Ra, Scarpa, A, Lawlor, Rt, Beghelli, S, Corbo, V, Scardoni, M, Bassi, C, Tempero, Ma.
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 395 (2012)
BMC Cancer
BMC Cancer
Background The receptor tyrosine kinase RON exhibits increased expression during pancreatic cancer progression and promotes migration, invasion and gemcitabine resistance of pancreatic cancer cells in experimental models. However, the prognostic sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282ade2f86adcce4d0711d5878efb69c
https://eprints.gla.ac.uk/155543/1/155543.pdf
https://eprints.gla.ac.uk/155543/1/155543.pdf
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