Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Favor David"'
Autor:
Ott, Gregory R., Favor, David A.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 15 September 2017 27(18):4238-4246
Autor:
Favor David, Gregory R. Ott
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(18)
Pyrrolo[2,1- f ][1,2,4]triazine, a unique N N bond-containing heterocycle with a bridgehead nitrogen, was first synthesized in the late 1970s but did not find utility until more than a decade later in the early 1990s when it was incorporated into C-n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a93f5d173b1e6a1feb331291b3c77c1
https://pubmed.ncbi.nlm.nih.gov/28801135
https://pubmed.ncbi.nlm.nih.gov/28801135
Autor:
David Ellis, Adam Stennett, Malcolm MacKenny, Gordon McMurray, Tony Kirkup, Favor David, Alan Daniel Brown, Wolfgang Klute
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:6118-6122
A new series of 2-(benzyloxy)benzamides are presented that are potent functional antagonists of TRPM8 and possess improved LipE and LE compared to the original lead. They were discovered through a series of compound libraries and we present a powerfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76cdc5c1cc1d3ade51a8677b316b7427
https://doi.org/10.1016/j.bmcl.2013.09.016
https://doi.org/10.1016/j.bmcl.2013.09.016
Autor:
Joseph T. Repine, Lorraine Kathleen Fay, Favor David, Hyacinth Akunne, Kim Nicholls, Bradley Snyder, Liming Zhang, Kevin A. Serpa, Douglas S. Johnson, Lawrence W. Fitzgerald, Andrew D. White, Chung Choi, Steven Z. Whetzel
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:2621-2625
The synthesis and structure-activity relationship (SAR) of a novel series of aryl piperazine napthyridinone D(2) partial agonists is described. Our goal was to optimize the affinities for the D(2), 5-HT(2A) and 5-HT(1A) receptors, such that the D(2)/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a73015fc859258fce499a6bc0925b0a
https://doi.org/10.1016/j.bmcl.2011.01.059
https://doi.org/10.1016/j.bmcl.2011.01.059
Autor:
Azhwarsamy Jeganathan, James J. Powers, Favor David, Rashmi Sharma, Trent Rankin, Chetan Pandit, Samarendra N. Maiti
Publikováno v:
Tetrahedron Letters. 50:1267-1269
The synthesis of a series of methyl-, fluoro-, and chloro-substituted 6-hydroxyisoindolin-1-ones is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c4bce890e24d24997d303da12bc49df
https://doi.org/10.1016/j.tetlet.2008.12.099
https://doi.org/10.1016/j.tetlet.2008.12.099
Autor:
Brown, Alan, Ellis, David, Favor, David A., Kirkup, Tony, Klute, Wolfgang, MacKenny, Malcolm, McMurray, Gordon, Stennett, Adam
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 15 November 2013 23(22):6118-6122
Autor:
Judy Yip, Douglas S. Johnson, Trent Rankin, Qizhu Ding, Andrew D. White, Samarendra N. Maiti, Favor David, Michael Stier, Joseph T. Repine
Publikováno v:
Tetrahedron Letters. 48:5539-5541
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a35a24b760322bba6c8de021bb573709
https://doi.org/10.1016/j.tetlet.2007.05.156
https://doi.org/10.1016/j.tetlet.2007.05.156
Publikováno v:
Tetrahedron Letters. 48:3039-3041
The synthesis of a series of regioisomeric chromanyl and dihydrobenzofuranyl piperazines is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::420c4c41ea2f541eb35daae0ac569f39
https://doi.org/10.1016/j.tetlet.2007.02.121
https://doi.org/10.1016/j.tetlet.2007.02.121
Akademický článek
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Autor:
Linda Strand, Duncan Armor, Kirstin Bess, Nicholas Pullen, C M Barker, Favor David, Christopher Phillips, Alan Daniel Brown, Andrew F. Bent, David Ellis, Michelle Styles, Stephen L. Irving, Malcolm MacKenny, Lee R. Roberts, Adam Stennett
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(19)
A series of p-hydroxybenzenesulphonamides ERβ receptor agonists were discovered and several compounds identified had excellent selectivity over the related ERα receptor. One of these, compound 11, had an interesting binding conformation determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d2d1fb134f200a0a2060b380e9caa2
https://pubmed.ncbi.nlm.nih.gov/21885279
https://pubmed.ncbi.nlm.nih.gov/21885279