Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Faustine, d'Orchymont"'
Autor:
Faustine d’Orchymont, Jason P. Holland
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Dual-modality imaging agents featuring both a radioactive complex for positron emission tomography (PET) and a fluorophore for optical fluorescence imaging (OFI) are crucial tools for reinforcing clinical diagnosis and intraoperative surgeri
Externí odkaz:
https://doaj.org/article/9bfcfc8056154137bbdd111e7c0ab396
Autor:
Lavinia E. Chiti, Benjamin Husi, Brian Park, Patricia Beer, Faustine D'Orchymont, Jason P. Holland, Mirja C. Nolff
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
IntroductionNear-infrared (NIR) fluorescence-guided surgery is increasingly utilized in humans and pets. As clinical imaging systems are optimized for Indocyanine green (ICG) detection, the usage of targeted dyes necessitates the validation of these
Externí odkaz:
https://doaj.org/article/f42fcbe30e964ee7918b35539a135e8b
Autor:
Daniel F. Earley, Amaury Guillou, Simon Klingler, Rachael Fay, Melanie Gut, Faustine d’Orchymont, Shamisa Behmaneshfar, Linus Reichert, Jason P. Holland
Publikováno v:
JACS Au, Vol 2, Iss 3, Pp 646-664 (2022)
Externí odkaz:
https://doaj.org/article/33351dd3157747ecaf4e4c64f6038143
Publikováno v:
Animals, Vol 13, Iss 14, p 2363 (2023)
Fluorescence-guided surgery can aid in the intraoperative visualization of target tissues, with promising applications in human and veterinary surgical oncology. The aim of this study was to evaluate the performances of two fluoresce camera systems,
Externí odkaz:
https://doaj.org/article/4c547813b89c4f1991d67f8af6a9d150
Autor:
Jennifer Lamb, Faustine d'Orchymont, Rachael Fay, Florian Gribi, Jose Esteban Flores, Melanie Gut, Simon Klingler, Patricia Pires, Jan Bühler, Shamisa Behmaneshfar, Amaury Guillou, Daniel F. Earley, Jason P. Holland
Publikováno v:
CHIMIA, Vol 74, Iss 12, Pp 946-952 (2020)
The synthesis, characterisation and application of radiolabelled compounds for use in diagnostic and therapeutic medicine requires a diverse skill set. This article highlights a selection of our ongoing projects that aim to provide new synthetic meth
Externí odkaz:
https://doaj.org/article/5d95a102eb33480c8a8fd891fd2c6f10
Autor:
Faustine D'Orchymont, Jason Holland
Publikováno v:
Chemical Science. 13:12713-12725
Radiolabelled monoclonal antibodies (mAbs) are a cornerstone of molecular diagnostic imaging and targeted radioimmunotherapy in nuclear medicine, but one of the major challenges in the field is to identify ways of reducing the radiation burden to pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f6a1348762f062e206a2c437284fcf
https://doi.org/10.1039/d2sc03928a
https://doi.org/10.1039/d2sc03928a
Autor:
Faustine D'Orchymont, Jason Holland
Publikováno v:
Angewandte Chemie International Edition. 61
Mechanically interlocked molecules present opportunities to construct therapeutic drugs and diagnostic imaging agents but harnessing supramolecular chemistry to make biologically active probes in water is a challenge. Here, we describe a rotaxane-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3b27f97a82b6946960b60e5f088ad6
https://doi.org/10.1002/anie.202204072
https://doi.org/10.1002/anie.202204072
Autor:
Faustine d'Orchymont, Jason P. Holland
Mechanically interlocked molecules present opportunities to construct therapeutic drugs and diagnostic imaging agents but harnessing supramolecular chemistry to make biologically active molecules in water is a challenge. Here, we describe a rotaxane-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e2e81eab455b836fa0722c74deee989
https://doi.org/10.26434/chemrxiv-2022-p9wgc-v2
https://doi.org/10.26434/chemrxiv-2022-p9wgc-v2
Autor:
Faustine d'Orchymont, Jason P. Holland
Mechanically interlocked molecules present opportunities to construct therapeutic drugs and diagnostic imaging agents but harnessing supramolecular chemistry to make biologically active molecules in water is a challenge. Here, we describe a rotaxane-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cff33c66b9aac9310e4355281190b839
https://doi.org/10.26434/chemrxiv-2022-p9wgc
https://doi.org/10.26434/chemrxiv-2022-p9wgc
Autor:
Daniel F, Earley, Amaury, Guillou, Simon, Klingler, Rachael, Fay, Melanie, Gut, Faustine, d'Orchymont, Shamisa, Behmaneshfar, Linus, Reichert, Jason P, Holland
Publikováno v:
JACS Au. 2(3)
The creation of discrete, covalent bonds between a protein and a functional molecule like a drug, fluorophore, or radiolabeled complex is essential for making state-of-the-art tools that find applications in basic science and clinical medicine. Photo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0b0f1cbde0e68ba770e4bdc057bf822
https://pubmed.ncbi.nlm.nih.gov/35373206
https://pubmed.ncbi.nlm.nih.gov/35373206