Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Faton Agani"'
Autor:
Richard L. Carpenter, Yi Jing, Qing Xu, Stephen S. Peiper, Jun He, Bing-Hua Jiang, Zhimin Lu, Xin Ru Wang, Ling-Zhi Liu, Qi Li, Faton Agani, Xu Qian
Publikováno v:
EMBO reports. 13:1116-1122
Overexpression of ERBB2 or ERBB3 is associated with cancer development and poor prognosis. In this study, we show that reactive oxygen species (ROS) induce both ERBB2 and ERBB3 expression in vitro and in vivo. We also identify that miR-199a and miR-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469e5f1a6885486888db93533c7ee2d4
https://doi.org/10.1038/embor.2012.162
https://doi.org/10.1038/embor.2012.162
Autor:
Ling-Zhi Liu, Faton Agani, Yi Jing, Yingxue Zhu, Bing-Hua Jiang, Nancy Lan Guo, Yon Rojanasakul, John B. Barnett, Yue Jiang
Publikováno v:
Toxicological Sciences. 125:10-19
Cadmium is categorized as a human carcinogen especially involved in lung cancers. Angiogenesis is considered a fundamental requirement for tumorigenesis, but the mechanisms underlying the tumor angiogenesis induced by cadmium are poorly understood. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18764d0636a0e6170147b044a4a6dfd
https://doi.org/10.1093/toxsci/kfr256
https://doi.org/10.1093/toxsci/kfr256
Publikováno v:
Journal of Biological Chemistry. 279:45643-45651
Vascular endothelial growth factor (VEGF) expression is elevated in ovarian and other cancer cells. However, the mechanism that causes the increase in VEGF expression still remains to be elucidated. In this study, we demonstrated that activation of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2795c727783ad99e46257cfbf410a469
https://doi.org/10.1074/jbc.m404097200
https://doi.org/10.1074/jbc.m404097200
Autor:
Nicole Jones, Faton Agani
Publikováno v:
Journal of Cellular Physiology. 196:326-333
Early growth response gene (Egr-1) is a stress response gene activated by various forms of stress and growth factor signaling. We report that supraphysiologic concentrations of O(2) (hyperoxia) induced Egr-1 mRNA and protein expression in cultured al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528c92247f0a8ed8a9a3efb88d0c2222
https://doi.org/10.1002/jcp.10308
https://doi.org/10.1002/jcp.10308
Publikováno v:
Journal of Biological Chemistry. 275:35863-35867
Hypoxia-inducible factor 1 (HIF-1) is a heterodimeric transcription factor that regulates transcriptional activation of several genes responsive to the lack of oxygen, including erythropoietin, vascular endothelial growth factor, glycolytic enzymes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952250e9af6524b659a101f22fd468f8
https://doi.org/10.1074/jbc.m005643200
https://doi.org/10.1074/jbc.m005643200
Autor:
Faton Agani, Narayan V. Iyer, Charles M. Wiener, Gregg L. Semenza, Bing-Hua Jiang, Aimee Yu, Sandra W. Leung
Publikováno v:
Chest. 114:40S-45S
Hypoxia-inducible factor 1 (HIF-1) mediates adaptive responses to hypoxia by activating the transcription of hundreds of target genes. The expression and activity of HIF-1 are oxygen-regulated, which provides a direct mechanism for transducing change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab2e49e6f40328a591601d713dfbb06e
https://doi.org/10.1378/chest.114.1_supplement.40s
https://doi.org/10.1378/chest.114.1_supplement.40s
Autor:
Bing-Hua Jiang, Gregg L. Semenza, Jo A. Forsythe, Faton Agani, Narayan V. Iyer, Sandra W. Leung, Robert D. Koos
Publikováno v:
Molecular and Cellular Biology. 16:4604-4613
Expression of vascular endothelial growth factor (VEGF) is induced in cells exposed to hypoxia or ischemia. Neovascularization stimulated by VEGF occurs in several important clinical contexts, including myocardial ischemia, retinal disease, and tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970466ce506436a0c489415f42d80224
https://doi.org/10.1128/mcb.16.9.4604
https://doi.org/10.1128/mcb.16.9.4604
Publikováno v:
Brain Research. 706:297-302
Previous investigators have reported that intracellular pH responds to hypoxia with a heterogenous pattern in individual glomus cells of the carotid body. The aim of the present study was to examine whether hypoxia had similar effects on cytosolic ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2407eb16f81cef8d82acaf94797139f
https://doi.org/10.1016/0006-8993(95)01122-6
https://doi.org/10.1016/0006-8993(95)01122-6
Autor:
Bing-Hua Jiang, Faton Agani
Publikováno v:
Current cancer drug targets. 13(3)
Studies on erythropoietin regulation led to discovery of hypoxia-inducible factor 1 (HIF-1), a transcription factor which is central component of oxygen sensing mechanism in mammalian cells. The number of HIF-1 and hypoxia-regulated target genes has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8c6167316393d6260713e2969470a4
https://pubmed.ncbi.nlm.nih.gov/23297826
https://pubmed.ncbi.nlm.nih.gov/23297826
Publikováno v:
Brain Research. 625:16-22
Recent studies suggest that nitric oxide (NO) may act as a chemical messenger in the nervous system. Since neurotransmitters are considered necessary for the sensory function of the carotid body, and molecular O 2 is a co-factor for NO synthesis, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46fedea746ca27cfaa466f85c2f16b5c
https://doi.org/10.1016/0006-8993(93)90132-7
https://doi.org/10.1016/0006-8993(93)90132-7