Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Fatna Ait, El Maate"'
Autor:
John A. F. Joosten, Roland J. Pieters, Rob M. J. Liskamp, Arwin J. Brouwer, Fatna Ait el Maate, Niels T. H. Tholen, Dirk T. S. Rijkers, G. Wilma van Esse
Publikováno v:
European Journal of Organic Chemistry. 2005:3182-3185
A facile and high-yielding synthesis of multivalent 1,4-disubstituted 1,2,3-triazole-linked glycodendrimers is described. Azido carbohydrates are linked by a CuI-catalyzed [3+2] cycloaddition reaction to dendritic acetylenes using microwave irradiati
Autor:
Fatna Ait el Maate, A. Salam Khan, John A. F. Joosten, Ulrich Dobrindt, Chantal C. M. Appeldoorn, Roland J. Pieters, Jörg Hacker, Rob M. J. Liskamp
Publikováno v:
Tetrahedron: Asymmetry. 16:361-372
A series of multivalent mannose containing compounds were prepared varying in size from small divalent, to 16-valent glycodenrimers and 21-valent glycopolymers. The molecules were approached via a common mannose building block. As scaffolds dendrimer
Autor:
Chantal C. M. Appeldoorn, Rob M. J. Liskamp, Sauli Haataja, Roland J. Pieters, Jukka Finne, Fatna Ait el Maate, Vuokko Loimaranta, John A. F. Joosten
Publikováno v:
Journal of Medicinal Chemistry. 47:6499-6508
A series of mono-, di-, and tetravalent galabiose (Galα1−4Gal) compounds were synthesized in good yields by coupling of a general carboxylic acid-bearing sugar building block to dendritic scaffolds based on the 3,5-di-(2-aminoethoxy)benzoic acid b
Autor:
Anna Lorenzen, Rosemarijn van Westhoven, Johannes Brussee, Thijs van den Hoven, Jacobien K. Von Frijtag Drabbe Künzel, Rianne A.F. de Ligt, Shelly Fujikawa, Fatna Ait El Maate, Pieter A. M. van der Klein, Ad P. IJzerman
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:139-149
Novel 3,8- and 8,9-disubstituted N6-cyclopentyladenine derivatives were synthesised in moderate overall yield from 6-chloropurine. The derivatives were made in an attempt to find a new neutral antagonist with high affinity for adenosine A1 receptors.
Publikováno v:
ChemInform. 35
A rapid, efficient and versatile microwave-assisted dibutylstannylene-mediated 3-O-alkylation method for galactosides was established. The alkylation reaction was significantly enhanced by microwave irradiation and allowed the use of an alkylating ag
Autor:
John A F, Joosten, Vuokko, Loimaranta, Chantal C M, Appeldoorn, Sauli, Haataja, Fatna Ait, El Maate, Rob M J, Liskamp, Jukka, Finne, Roland J, Pieters
Publikováno v:
Journal of medicinal chemistry. 47(26)
A series of mono-, di-, and tetravalent galabiose (Galalpha1-4Gal) compounds were synthesized in good yields by coupling of a general carboxylic acid-bearing sugar building block to dendritic scaffolds based on the 3,5-di-(2-aminoethoxy)benzoic acid
Autor:
Rianne A F, de Ligt, Pieter A M, van der Klein, Jacobien K, von Frijtag Drabbe Künzel, Anna, Lorenzen, Fatna, Ait El Maate, Shelly, Fujikawa, Rosemarijn, van Westhoven, Thijs, van den Hoven, Johannes, Brussee, Ad P, IJzerman
Publikováno v:
Bioorganicmedicinal chemistry. 12(1)
Novel 3,8- and 8,9-disubstituted N(6)-cyclopentyladenine derivatives were synthesised in moderate overall yield from 6-chloropurine. The derivatives were made in an attempt to find a new neutral antagonist with high affinity for adenosine A(1) recept