Výsledky vyhledávání - "Fatma M. Manhi"

Uses of dimedone to synthesis pyrazole, isoxazole and thiophene derivatives with antiproliferative, tyrosine kinase and Pim-1 kinase inhibitions

Autor: Fatma M. Manhi, Amal Abdelwahab, Rafat M. Mohareb, Mahmoud Ali Abdelaziz Mahmoud

Publikováno v: Medicinal Chemistry Research. 29:1536-1551

We are aiming in this work to synthesize target molecules not only possess antitumor activities but also kinase inhibitors. The target molecules were obtained from dimedone, which reacted with triethoxymethane to produce a product that is capable for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e98cf1f4a5ce49b52f80ea4a1f01481
https://doi.org/10.1007/s00044-020-02579-4

Zobrazit plný text záznamu

1,2,4-Trisubstituted imidazolinones with dual carbonic anhydrase and p38 mitogen-activated protein kinase inhibitory activity

Autor: Emanuela Berrino, Hanan H. Georgey, Fatma M. Manhi, Nehad A. Mohamed, Walaa R. Mahmoud, Claudiu T. Supuran

Publikováno v: Bioorganic chemistry. 82

Various 1,2,4 trisubstituted imidazolin-5-one derivatives were synthesized and evaluated for their inhibitory activity against p38 mitogen-activated protein kinase (p38MAPK) and carbonic anhydrase (CA) enzymes aiming to explore potential dual inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c807476ee5cd6f5d827f35a1a14ad97f
https://pubmed.ncbi.nlm.nih.gov/30312865

Zobrazit plný text záznamu

Studies on the reactivity of fused thiazole toward nucleophilic reagents: Synthesis of new thiazolo-derivatives of potential antischistosomal activity

Autor: Fatma M. Manhi, Madiha Mahmoud

Publikováno v: Heteroatom Chemistry. 16:121-131

Schistosomiasis is considered one of the most important human helminth infection in terms of morbidity and infectivity (Chitsulo et al. Acta Trop 2000, 77, 41; Engles et al. Acta Trop 2002, 82, 139; Shelly et al. Mol Biochem Parasitol 1993, 60, 93).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03719cad9d2a40db066e035f1f839d7
https://doi.org/10.1002/hc.20072

Zobrazit plný text záznamu

Reaction of ethyl 2-diazo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate with 3-iminobutyronitrile: synthesis of pyridazines, thiophenes, and their fused derivatives

Autor: Rafat M. Mohareb, Fatma M. Manhi

Publikováno v: Heteroatom Chemistry. 11:403-412

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::763f55e0b20b4ad401250627ff5c13dd
https://doi.org/10.1002/1098-1071(2000)11:6<403::aid-hc8>3.0.co

Zobrazit plný text záznamu

HYDRAZONES IN HETEROCYCLIC SYNTHESIS; SYNTHESIS OF 1,3,4-THIADIAZOLE DERIVATIVES

Autor: Ayman Wahba Erian, Fatma M. Manhi, Salem E. Zayed, Mohamed Hilmy Elnagdi, Fatma Ahmed Ali

Publikováno v: Phosphorus, Sulfur, and Silicon and the Related Elements. 133:127-139

A new synthesis of 1,3,4-thiadiazoles has been achieved. The reactivity of certain alkylheterocycles towards electrophilic reagents are reported.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f5127e5b1f3009bffda1af6a171efdc
https://doi.org/10.1080/10426509808032460

Zobrazit plný text záznamu

ChemInform Abstract: A Novel Synthesis of Fused Pyrazole Systems as Antimicrobial Agents

Autor: Ayman Wahba Erian, Fatma M. Manhi, S. El‐Gohary, F. A. Ali

Publikováno v: ChemInform. 30

The pyrazolo[3,4-b]pyridine derivatives 3 could be prepared by condensing compounds 1 with the 3-aminopyrazolone derivative 2. The pyrazolo[5,2-b]-1,3-oxazine derivative 11 and polyfunctionally substituted 1,4-dihydropyridines 15, 18 were also synthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b48a756c3205e3baffb9be8df2f4fe42
https://doi.org/10.1002/chin.199909170

Zobrazit plný text záznamu

Studies with Polyfunctionally Substituted Heterocycles: Novel Syntheses of Pyrido[4,3-d]pyridazines and of Pyrido[3,4-d]pyridazines

Autor: Salem E. Zayed, Mohamed Hilmy Elnagdi, Fatma M. Manhi, Fatma Ahmed Ali

Publikováno v: Collection of Czechoslovak Chemical Communications. 57:1770-1774

As a part of our programme aimed at developing efficient syntheses of polyfunctionally substituted azines and condensed azines, we have in the past reported efficient syntheses of compounds I-III. In conjunction of this work we report results of our

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5bb1ad5e04e774ac3b2b54dfa8bcb65b
https://doi.org/10.1135/cccc19921770

Zobrazit plný text záznamu

ChemInform Abstract: Reaction of Ethyl 2-Diazo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate with 3-Iminobutyronitrile: Synthesis of Pyridazines, Thiophenes, and Their Fused Derivatives

Autor: Fatma M. Manhi, Rafat M. Mohareb

Publikováno v: ChemInform. 32

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6171ac5a2fba90059ebe22055026446d
https://doi.org/10.1002/chin.200104165

Zobrazit plný text záznamu

Ketoketenegem-Dithiols in the Synthesis of Pyrimidine and Pyrazole Derivatives Pyrimidin- und Pyrazol-Derivate aus geminalen Dithiolen eines Ketoketens

Autor: Mohamed Hassan, Salem E. Zayed, Ibrahim A. Hussin, Fatma M. Manhi

Publikováno v: Archiv der Pharmazie. 322:841-842

The ketoketene dimercaptal 1 prepared from 4-acetylbiphenyl and CS21) is a subject of current interest. The reaction of α-ketoketene-S,S-acetals and α-cyanoketene-S,S-acetals with guanidine and thiourea to give pyrimidine derivatives was reported2,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b472b0c7c784a71f2ad1d0382e04a3de
https://doi.org/10.1002/ardp.19893221116

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání