Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Fatma Cankara"'
Conformational diversity and protein–protein interfaces in drug repurposing in Ras signaling pathway
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract We focus on drug repurposing in the Ras signaling pathway, considering structural similarities of protein–protein interfaces. The interfaces formed by physically interacting proteins are found from PDB if available and via PRISM (PRotein I
Externí odkaz:
https://doaj.org/article/70300b18ef7b452c89a30866895f8214
Autor:
Fatma Cankara, Tunca Doğan
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4743-4758 (2023)
Background: Genomic variations may cause deleterious effects on protein functionality and perturb biological processes. Elucidating the effects of variations is critical for developing novel treatment strategies for diseases of genetic origin. Comput
Externí odkaz:
https://doaj.org/article/d9acbe9b594d4b2e863104bc44be4cbc
Autor:
Fatma Cankara, Tunca Doğan
MotivationGenomic variations may cause deleterious effects on protein functionality and perturb biological processes. Elucidating the effects of variations is critical for developing novel treatment strategies for diseases of genetic origin. Computat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1f1c99aed7ccdb8a35f4be39c3c03b0
https://doi.org/10.1101/2022.11.03.514934
https://doi.org/10.1101/2022.11.03.514934
Publikováno v:
Current Opinion in Structural Biology
Host-microbiome interactions play significant roles in human health and disease. Artificial intelligence approaches have been developed to better understand and predict the molecular interplay between the host and its microbiome. Here, we review rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf765e8f26fe9586c391a91d334dc0bc
https://doi.org/10.1016/j.sbi.2022.102328
https://doi.org/10.1016/j.sbi.2022.102328