Study of the reactivity of aminocyanopyrazoles and evaluation of the mitochondrial reductive function of some products

Autor: Soumaya Bellili, Nicholas J. Coltman, Nikolas J. Hodges, Fatma Allouche

Publikováno v: Heterocyclic Communications. 28:11-17

This research investigated the general high-throughput synthetic protocol for the accelerated synthesis of functionalized trifluoromethylpyrazolopyrimidines 3 and N-(5-cyano-3-methyl-1-phenyl-1H-pyrazol-4-yl) benzamide 4 from aminocyanopyrazole 1 pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::118c855d20d50c57bc70264e7b9a2e83
https://doi.org/10.1515/hc-2022-0001

Study on Synthesis and Biological Activities of Novel 1,7-dihydropyrazolo[3,4-d] imidazo[1,2-f] pyrimidines

Autor: Fatma Allouche

Aiming to synthesize new anti-inflammatory 1,7-dihydropyrazolo[3,4-d] imidazo[1,2-f] pyrimidine 5 from aminocyanopyrazole, a forthright method has been developed. It is for their anti-inflammatory, gastroprotective, analgesic, antioxidant and antican

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2722c7d71a301eea40787a5b71e5617f
https://doi.org/10.9734/bpi/cacb/v4/8112d

Reactivity of 5-aminopyrazoles bearing a cyclopropyl group at C3-position in palladium-catalyzed direct C4-arylation

Autor: Henri Doucet, Jean-François Soulé, Fatma Allouche, Ameni Sidhom

Publikováno v: Catalysis Communications
Catalysis Communications, Elsevier, 2018, 115, pp.55-58. ⟨10.1016/j.catcom.2018.07.008⟩
Catalysis Communications, 2018, 115, pp.55-58. ⟨10.1016/j.catcom.2018.07.008⟩

International audience; Pyrazole derivatives bearing a cyclopropyl group at C3-position and an amino substituent at C5 were successfully employed in palladium-catalyzed direct arylations. These couplings were performed using air-stable PdCl (C3H5)(dp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb11270864fe8961737b4f65347c018
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01879771

Synthesis and biological evaluation of new pyrazolo[3,4-d]pyrimidine derivatives

Autor: Asma Agrebi, Fakher Chabchoub, Fatma Allouche, Hamadi Fetoui

Publikováno v: Mediterranean Journal of Chemistry, Vol 3, Iss 2, Pp 864-876 (2014)

Several new pyrazolopyrimidine compounds were achieved from aminocyanopyarazole 1. The starting material 1 was initially coupled with orthoester at refluxed with various primary amines, ammonia, hydrazines and hydroxylamine to furnish a series of pyr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81596f8d6eb7b131d9ccdcb86f9086b4
https://doi.org/10.13171/mjc.3.2.2014.13.05.23

Synthesis, Antibacterial, and Antifungal Activities of Imidazo[2,1-c][1,2,4]triazoles and 1,2,4-Triazolo[4,3-a]pyrimidinones

Autor: Imen Zouari, Fakher Chabchoub, Monia Aouali, Dhekra Mhalla, Mohamed Trigui, Fatma Allouche

Publikováno v: Synthetic Communications. 44:748-756

A straightforward method has been developed for the synthesis of 1-phenyl-imidazo [2,1-c][1,2,4]triazole derivatives 5a–j and 1-phenyl-[1,2,4]triazolo[4,3-a]pyrimidinones derivatives 6a–g starting from 5-amino-1-phenyl[1,2,4]triazole and p-toluen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308c4fc2a4201d839fb4b3c1c978cd74
https://doi.org/10.1080/00397911.2013.804576