Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fatma Ahmet"'
Autor:
Fatma Ahmet, Jessica Li, Robert De Rose, Stephen J. Kent, Ken Shortman, Andres M Salazar, Caetano Reis e Sousa, William R. Heath, Andrew G. Brooks, Irina Caminschi, Lucy C. Sullivan, Mireille H. Lahoud
Publikováno v:
European Journal of Immunology. 45:854-864
Targeting antigens to dendritic cell (DC) surface receptors using antibodies has been successfully used to generate strong immune responses and is currently in clinical trials for cancer immunotherapy. Whilst cancer immunotherapy focuses on the induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::540335339d715b749b8139a23f16b31c
https://doi.org/10.1002/eji.201445127
https://doi.org/10.1002/eji.201445127
Autor:
Irina Caminschi, William R. Heath, Meredith O'Keeffe, Mireille H. Lahoud, Fatma Ahmet, Jessica Li
Publikováno v:
Molecular immunology. 81
We have previously shown that DEC205, a surface receptor expressed at high levels on CD8+DC, is able to capture synthetic CpG oligonucleotides (ODN) and is required for optimal responsiveness. However, even in the absence of DEC205, CD8+DC are able t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2655664cc2d2be82b6c926717c9e033
https://pubmed.ncbi.nlm.nih.gov/27974262
https://pubmed.ncbi.nlm.nih.gov/27974262
Autor:
David Vremec, Kenneth M. Murphy, Mireille H. Lahoud, Ken Shortman, Fatma Ahmet, Irina Caminschi, Jose A Villadangos, William R. Heath
Publikováno v:
Molecular Immunology. 50:9-17
Injection of antigens coupled to antibodies against the dendritic cell (DC) surface molecule Clec9A has been shown to produce strongly enhanced antibody responses even without co-administration of adjuvants, via antigen presentation by DC on MHC clas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c388e4f077d271428490fd8b18920c76
https://doi.org/10.1016/j.molimm.2011.11.008
https://doi.org/10.1016/j.molimm.2011.11.008
Autor:
Wei Shi, Chin-Nien Lee, Irina Caminschi, Susie Kitsoulis, Scott N. Mueller, Andrew M. Lew, Ken Shortman, Soo San Wan, Gordon K. Smyth, David Vremec, Fatma Ahmet, Belinda Phipson, Yu Kato, Mireille H. Lahoud, Gayle M. Davey, William R. Heath
Publikováno v:
The Journal of Immunology. 187:842-850
Three surface molecules of mouse CD8+ dendritic cells (DCs), also found on the equivalent human DC subpopulation, were compared as targets for Ab-mediated delivery of Ags, a developing strategy for vaccination. For the production of cytotoxic T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b28ffd48d51adde026fdaa9fcf27441
https://doi.org/10.4049/jimmunol.1101176
https://doi.org/10.4049/jimmunol.1101176
Autor:
Patricia L Mottram, David Vremec, Anna I Proietto, Li Wu, Hal Braley, Alexandra Rizzitelli, Ken Shortman, Fatma Ahmet, Joo Shin Teh, Nicholas C. van de Velde, Serani Lh van Dommelen, Susie Kitsoulis, Kent Jensen, Andrew M. Lew, Ian K. Campbell, Irina Caminschi, Mark D. Wright, Eugene Maraskovsky, Gayle M. Davey, Jennifer Chi Yi Lo, Mireille H. Lahoud, William R. Heath
Publikováno v:
Blood. 112:3264-3273
A novel dendritic cell (DC)–restricted molecule, Clec9A, was identified by gene expression profiling of mouse DC subtypes. Based on sequence similarity, a human ortholog was identified. Clec9A encodes a type II membrane protein with a single extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7784617e212baefbb458935c17d28fd
https://doi.org/10.1182/blood-2008-05-155176
https://doi.org/10.1182/blood-2008-05-155176
Autor:
Jessica, Li, Fatma, Ahmet, Lucy C, Sullivan, Andrew G, Brooks, Stephen J, Kent, Robert, De Rose, Andres M, Salazar, Caetano, Reis e Sousa, Ken, Shortman, Mireille H, Lahoud, William R, Heath, Irina, Caminschi
Publikováno v:
European journal of immunology. 45(3)
Targeting antigens to dendritic cell (DC) surface receptors using antibodies has been successfully used to generate strong immune responses and is currently in clinical trials for cancer immunotherapy. Whilst cancer immunotherapy focuses on the induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd6bc67a0a6fe5febe39bf6e31954b84
https://pubmed.ncbi.nlm.nih.gov/25487143
https://pubmed.ncbi.nlm.nih.gov/25487143
Autor:
Richard Berry, Jamie Rossjohn, Antonia N. Policheni, Irina Caminschi, Justine D. Mintern, Chin-Nien Lee, Andrew G. Brooks, Michel C. Nussenzweig, William R. Heath, Jose A Villadangos, Meredith O'Keeffe, Jian-Guo Zhang, Simone Meuter, Katryn J. Stacey, Ken Shortman, Lucy C. Sullivan, Javier Vega-Ramos, Susie Kitsoulis, Mireille H. Lahoud, Nicos A. Nicola, Fatma Ahmet
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Synthetic CpG oligonucleotides (ODN) have potent immunostimulatory properties exploited in clinical vaccine trials. How CpG ODN are captured and delivered to the intracellular receptor TLR9, however, has been elusive. Here we show that DEC-205, a mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588f94d19d6344fb235deaa66b0c04d1
https://pubmed.ncbi.nlm.nih.gov/22988114
https://pubmed.ncbi.nlm.nih.gov/22988114
Autor:
Ian D. Walker, Mark D. Wright, Mireille H. Lahoud, William R. Heath, Ken Shortman, Priyanka Sathe, Li Wu, Hal Braley, Anna I Proietto, Hsuen Wen Chang, Irina Caminschi, Fatma Ahmet, Liv Eidsmo, Suzanne Pietersz, Eugene Maraskovsky, Andrew M. Lew, Susie Kitsoulis
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 182(12)
We have cloned the mouse and human C-type lectin Clec12A, expressed both, and produced mAb recognizing both. Mouse Clec12A is highly expressed on splenic CD8+ dendritic cells (DC) and plasmacytoid DC. A proportion of CD8−DC also expresses lower lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc6d59d3fe3b9ea047733b7872f3c65
https://pubmed.ncbi.nlm.nih.gov/19494282
https://pubmed.ncbi.nlm.nih.gov/19494282
Autor:
Diana S. Hansen, Gayle M. Davey, Ken Shortman, Mark J. Smyth, William R. Heath, Meredith O'Keeffe, Jose A Villadangos, Suzanne Pietersz, Stephen L. Nutt, David Vremec, Fatma Ahmet, Mireille H. Lahoud, Louis Schofield, Sammy Bedoui, Irina Caminschi, Klaus Heger, Jason Brady
Publikováno v:
The Journal of Experimental Medicine
Interferon-producing killer dendritic cells (IKDCs) have been described as possessing the lytic potential of NK cells and the antigen-presenting capacity of dendritic cells (DCs). In this study, we examine the lytic function and antigen-presenting ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5784722cf8eaf9eeeabeffc761d7134
https://pubmed.ncbi.nlm.nih.gov/17923506
https://pubmed.ncbi.nlm.nih.gov/17923506