Zobrazeno 1 - 10 of 86 pro vyhledávání: '"Fatima Z, Basha"'
1
Suppression of COX-2/PGE
Autor: Humera, Jahan, Nimra Naz, Siddiqui, Shazia, Iqbal, Fatima Z, Basha, Sadia, Shaikh, Marina, Pizzi, M Iqbal, Choudhary
Publikováno v: Cellular signalling. 97
Chronic hyperglycemia favours the formation of advanced glycation end products (AGEs) which are responsible of many diabetic vascular complications. Keeping in view the medicinal properties of the1,2,3-triazole-conjugated analogs, the present study w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2b6b6e5949d98b22cb73611bdbcdc926
https://pubmed.ncbi.nlm.nih.gov/35640822
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2
Indole-linked 1,2,3-triazole derivatives efficiently modulate COX-2 protein and PGE
Autor: Humera, Jahan, Nimra Naz, Siddiqui, Shazia, Iqbal, Fatima Z, Basha, Maria Aqeel, Khan, Tooba, Aslam, M Iqbal, Choudhary
Publikováno v: Life sciences. 291
AGEs augment inflammatory responses by activating inflammatory cascade in monocytes, and hence lead to vascular dysfunction. The current study aims to study a plausible role and mechanism of a new library of indole-tethered 1,2,3-triazoles 2-13 in AG
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::11d8c35ec4ae5585b6db8f09bebaf24f
https://pubmed.ncbi.nlm.nih.gov/34990649
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3
Microwave-Assisted Organic Synthesis, structure–activity relationship, kinetics and molecular docking studies of non-cytotoxic benzamide derivatives as selective butyrylcholinesterase inhibitors
Autor: Shama Kanwal, Humaira Zafar, M. Iqbal Choudhary, Asma Khatoon, Maria Aqeel Khan, Sheeba Wajid, Atta-ur-Rahman, Fatima Z. Basha
Publikováno v: Bioorganic & Medicinal Chemistry. 27:4030-4040
A series of benzamide derivatives 1–12 with various functional groups (–H, –Br, –F, –OCH3, –OC2H5, and –NO2) was synthesized using an economic, and facile Microwave-Assisted Organic Synthesis, and evaluated for acetylcholinesterase (ACH
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290ec1daff52fc47b5cca132aea01038
https://doi.org/10.1016/j.bmc.2019.07.015
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8
Akademický článek
4-Methoxy-N-(4-methoxy-2-nitrophenyl)benzamide
Autor: Muhammad Arshad, Sammer Yousuf, Sumayya Saeed, Fatima Z. Basha
Publikováno v: Acta Crystallographica Section E, Vol 68, Iss 10, Pp o3028-o3028 (2012)
In the title compound, C15H14N2O5, the central amide C—C(=O)—N—C unit forms dihedral angles of 28.17 (13) and 26.47 (13)° with the two benzene rings, whereas the two benzene rings are almost coplanar, making a dihedral angle of 4.52 (13)°. Th
Externí odkaz: https://doaj.org/article/e494ce8312934daca1aa598cfe58b9ac
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9
Akademický článek
2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl methanesulfonate
Autor: Sammer Yousuf, Aurang Zeb, Farhana Batool, Fatima Z. Basha
Publikováno v: Acta Crystallographica Section E, Vol 68, Iss 9, Pp o2781-o2781 (2012)
The asymmetric unit of the title compound, C7H11N3O5S, contains two independent molecules with virtually identical conformations. The imidazole rings of both molecules are essentially planar (r.m.s. deviations = 0.0019 and 0.0038 Å), with a dihedral
Externí odkaz: https://doaj.org/article/d7adfb7df3924287b389bd843b07a8e6
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10
Akademický článek
2-Azido-1-(4-methylphenyl)ethanone
Autor: Muhammad Arshad, Sammer Yousuf, Hafiza Madiha Butt, Sumayya Saeed, Fatima Z. Basha
Publikováno v: Acta Crystallographica Section E, Vol 68, Iss 6, Pp o1608-o1608 (2012)
In the molecule of the title compound, C9H9N3O, the angle formed by the least-squares line through the azide group with the normal to the plane of the benzene plane ring is 46.62 (16)°. The crystal structure features C—H...O hydrogen bonds, which
Externí odkaz: https://doaj.org/article/83aa1309f867473b8bde21503a10987b
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