Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Fatima H, Labeed"'
Autor:
Michael Pycraft Hughes, Krista S. P. Clarke, Rashedul Hoque, Oreoluwa V. Griffiths, Emily J. Kruchek, Matthew P. Johnson, Muhammad Hamza Tariq, Nupur Kohli, Rebecca Lewis, Fatima H. Labeed
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Measurement of cellular resting membrane potential (RMP) is important in understanding ion channels and their role in regulation of cell function across a wide range of cell types. However, methods available for the measurement of RMP (inclu
Externí odkaz:
https://doaj.org/article/3c700063f254470bad48d7d5caec1487
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Electrical aspects of cell function manifest in many ways. The most widely studied is the cell membrane potential, V m , but others include the conductance and capacitance of the membrane, the conductance of the enclosed cytoplasm, as well a
Externí odkaz:
https://doaj.org/article/5930e4a115244b8bb54ac97e4bf8acd7
Autor:
Michael Pycraft Hughes, Emily J. Kruchek, Andrew D. Beale, Stephen J. Kitcatt, Sara Qureshi, Zachary P. Trott, Oriane Charbonnel, Paul A. Agbaje, Erin A. Henslee, Robert A. Dorey, Rebecca Lewis, Fatima H. Labeed
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Even in nonexcitable cells, the membrane potential V m is fundamental to cell function, with roles from ion channel regulation, development, to cancer metastasis. V m arises from transmembrane ion concentration gradients; standard models ass
Externí odkaz:
https://doaj.org/article/57b96bc6687c43699ffc369c723f0e5f
Autor:
Fatima H. Labeed, Andrew D. Beale, Petra Schneider, Stephen J. Kitcatt, Emily J. Kruchek, Sarah E. Reece
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Circadian rhythms are biological adaptations to the day-night cycle, whereby cells adapt to changes in the external environment or internal physiology according to the time of day. Whilst many cellular clock mechanisms involve gene expression feedbac
Externí odkaz:
https://doaj.org/article/b3688b3f1d3f4a389503e94f6ebe691c
Autor:
Michael P. Hughes, Fatima H. Labeed, Kai F. Hoettges, Stephen Porter, Valeria Mercadante, Nicholas Kalavrezos, Colin Liew, James A. McCaul, Raghav Kulkarni, James Cymerman, Cyrus Kerawala, Julie Barber, Mark P. Lewis, Stefano Fedele
Publikováno v:
Journal of Oral Pathology & Medicine. 52:305-314
Autor:
Erin A. Henslee, Priya Crosby, Stephen J. Kitcatt, Jack S. W. Parry, Andrea Bernardini, Rula G. Abdallat, Gabriella Braun, Henry O. Fatoyinbo, Esther J. Harrison, Rachel S. Edgar, Kai F. Hoettges, Akhilesh B. Reddy, Rita I. Jabr, Malcolm von Schantz, John S. O’Neill, Fatima H. Labeed
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Circadian rhythms usually rely on cyclic variations in gene expression. Red blood cells, however, display circadian rhythms while being devoid of nuclear DNA. Here, Henslee and colleagues show that circadian rhythms in isolated human red blood cells
Externí odkaz:
https://doaj.org/article/3b9cc98ebe9f4f4a828664161f701abc
Autor:
Michael Pycraft Hughes, Emily J. Kruchek, Jonathan M. Gibbins, Oreoluwa V. Griffiths, Bader Abdal, Fatima H. Labeed
Publikováno v:
Bioelectricity. 4:153-159
Publikováno v:
Micromachines, Vol 12, Iss 8, p 949 (2021)
Diseases such as osteoarthritis (OA) are commonly characterized at the molecular scale by gene expression and subsequent protein production; likewise, the effects of pharmaceutical interventions are typically characterized by the effects of molecular
Externí odkaz:
https://doaj.org/article/f9d328591fe24af89fbaeefd4a488bc0
Autor:
Capucine Martin, Jonathan D. Johnston, Erin A. Henslee, Daan R. van der Veen, Fatima H. Labeed
Publikováno v:
ELECTROPHORESIS. 43:1337-1346
Adipocytes are energy stores of the body which also play a role in physiological regulation and homeostasis through their endocrine activity. Adipocyte circadian clocks drive rhythms in gene expression, and dysregulation of these circadian rhythms as
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2482
Dielectrophoresis (DEP) enables the measurement of population-level electrophysiology in many cell types by examining their interaction with an externally applied electric field. Here we describe the application of DEP to the measurement of circadian