Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Fatima Girach"'
Publikováno v:
Cell Reports, Vol 5, Iss 5, Pp 1294-1301 (2013)
The rapid, activity-dependent quantal presynaptic release of neurotransmitter is vital for brain function. The complex process of vesicle priming, fusion, and retrieval is very precisely controlled and requires the spatiotemporal coordination of mult
Externí odkaz:
https://doaj.org/article/45ae8e2027b342138c093489ca6ea88d
Autor:
Konstantinos Meletis, Andras G. Miklosi, Fatima Girach, Gloria Arque, Tibor Harkany, János Fuzik, Alán Alpár, Roman A. Romanov, Sabah Rehman, Solomiia Korchynska, Gabor G. Kovacs, Yuchio Yanagawa, Tomas G. M. Hökfelt, János Hanics, Ludwig Wagner
Psychostimulant use is an ever-increasing socioeconomic burden, including a dramatic rise during pregnancy. Nevertheless, brain-wide effects of psychostimulant exposure are incompletely understood. Here, we performed Fos-CreERT2-based activity mappin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da51dc2f6d222d6b3cacf675487280a8
Autor:
Roman A. Romanov, Sabah Rehman, Alán Alpár, János Fuzik, Tomas G. M. Hökfelt, Konstantinos Meletis, Solomiia Korchynska, Gabor G. Kovacs, Andras G. Miklosi, Tibor Harkany, Yuchio Yanagawa, Gloria Arque, Ludwig Wagner, Fatima Girach, János Hanics
Publikováno v:
Proceedings of the National Academy of Sciences
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Psychostimulant use is an ever-increasing socioeconomic burden, including a dramatic rise during pregnancy. Nevertheless, brain-wide effects of psychostimulant exposure are incompletely understood. Here, we performed Fos-CreER(T2)–based activity ma
Autor:
Jan Mulder, Christian Schwindling, Peer Wulff, Tibor Harkany, Ailey K. Crow, Christian Broberger, Roman A. Romanov, Brian Hsueh, Tamas L. Horvath, André F. Rendeiro, Sten Linnarsson, Daniela Calvigioni, Yuchio Yanagawa, Zoltán Máté, Henrik Martens, Frédéric Clotman, Jaideep S. Bains, Raju Tomer, Mathias Uhlén, Matthias Farlik, Fatima Girach, Tomas Hökfelt, Erik Keimpema, Amit Zeisel, Christoph Bock, Karl Deisseroth, Ming-Dong Zhang, Joanne Bakker, Alán Alpár, Gábor Szabó, Arash Hellysaz
Publikováno v:
Nature Neuroscience, Vol. 20, no. 2, p. 176-188 (Feb 2017)
Nature Neuroscience
Nature Neuroscience
The hypothalamus contains the highest diversity of neurons in the brain. Many of these neurons can co-release neurotransmitters and neuropeptides in a use-dependent manner. Investigators have hitherto relied on candidate protein-based tools to correl
Autor:
Jan Mulder, Tibor Harkany, Katarzyna Malenczyk, Tomas Hökfelt, Fatima Girach, Mathias Uhlén, Masahiko Watanabe, Lotta Borgius, Ming-Dong Zhang, Valentina Cinquina, Csaba Adori, Changgeng Peng, Peter Löw, Patrik Ernfors, Ole Kiehn, Jie Su, Nicholas Mitsios
Publikováno v:
Journal of Clinical Investigation
Pain signals are transmitted by multisynaptic glutamatergic pathways. Their first synapse between primary nociceptors and excitatory spinal interneurons gates the sensory load. In this pathway, glutamate release is orchestrated by Ca2+-sensor protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215be8df6a9fa497bc110f3674c0ec09
https://europepmc.org/articles/PMC6118643/
https://europepmc.org/articles/PMC6118643/
Autor:
Jan Mulder, Erzsébet Borók, Ludwig Wagner, Tibor Harkany, Roman A. Romanov, Edit Szodorai, Åsa Segerstolpe, Giuseppe Tortoriello, Gert Lubec, Robert Schnell, Stefan Kubicek, Petter Storm, Katarzyna Malenczyk, Gábor Szabó, Tomas Hökfelt, Leif Groop, Fatima Girach, Vincenzo Di Marzo, Fabiana Piscitelli, Rickard Sandberg
Publikováno v:
EMBO journal
36 (2017): 2107–2125. doi:10.15252/embj.201695347
info:cnr-pdr/source/autori:Malenczyk K.; Girach F.; Szodorai E.; Storm P.; Segerstolpe A.; Tortoriello G.; Schnell R.; Mulder J.; Romanov R.A.; Borok E.; Piscitelli F.; Di Marzo V.; Szabo G.; Sandberg R.; Kubicek S.; Lubec G.; Hokfelt T.; Wagner L.; Groop L.; Harkany T./titolo:A TRPV1-to-secretagogin regulatory axis controls pancreatic ?-cell survival by modulating protein turnover/doi:10.15252%2Fembj.201695347/rivista:EMBO journal (Print)/anno:2017/pagina_da:2107/pagina_a:2125/intervallo_pagine:2107–2125/volume:36
The EMBO Journal
36 (2017): 2107–2125. doi:10.15252/embj.201695347
info:cnr-pdr/source/autori:Malenczyk K.; Girach F.; Szodorai E.; Storm P.; Segerstolpe A.; Tortoriello G.; Schnell R.; Mulder J.; Romanov R.A.; Borok E.; Piscitelli F.; Di Marzo V.; Szabo G.; Sandberg R.; Kubicek S.; Lubec G.; Hokfelt T.; Wagner L.; Groop L.; Harkany T./titolo:A TRPV1-to-secretagogin regulatory axis controls pancreatic ?-cell survival by modulating protein turnover/doi:10.15252%2Fembj.201695347/rivista:EMBO journal (Print)/anno:2017/pagina_da:2107/pagina_a:2125/intervallo_pagine:2107–2125/volume:36
The EMBO Journal
Ca 2+ ‐sensor proteins are generally implicated in insulin release through SNARE interactions. Here, secretagogin, whose expression in human pancreatic islets correlates with their insulin content and the incidence of type 2 diabetes, is shown to o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b42c85dc8c370eae6dfc4d435d108e7
https://publications.cnr.it/doc/380829
https://publications.cnr.it/doc/380829
Publikováno v:
Cell Reports, Vol 5, Iss 5, Pp 1294-1301 (2013)
Cell Reports
Cell Reports
Summary The rapid, activity-dependent quantal presynaptic release of neurotransmitter is vital for brain function. The complex process of vesicle priming, fusion, and retrieval is very precisely controlled and requires the spatiotemporal coordination
Autor:
Erik Keimpema, Daniela Calvigioni, Andrea Varro, Yuchio Yanagawa, Chris J. McBain, Graham J. Dockray, Ming-Dong Zhang, Zoltán Máté, Tibor Harkany, Tomas Hökfelt, Gábor Szabó, Johannes Beiersdorf, Fatima Girach, János Fuzik, Christian Schwindling
Publikováno v:
Cerebral Cortex
Although extensively studied postnatally, the functional differentiation of cholecystokinin (CCK)-containing interneurons en route towards the cerebral cortex during fetal development is incompletely understood. Here, we used CCKBAC/DsRed mice encodi
Publikováno v:
Scientific Reports.
Autor:
Michaela J. Heimann, Keri L Hildick, Emi Ashikaga, Fernando Josa-Prado, Philip Rubin, Leo T. H. Tang, Fatima Girach, Ruth E. Carmichael, Jia Luo, Paul Bishop, Kevin A. Wilkinson, Jeremy M. Henley
Publikováno v:
NeuroMolecular Medicine
Timely and efficient information transfer at synapses is fundamental to brain function. Synapses are highly dynamic structures that exhibit long-lasting activity-dependent alterations to their structure and transmission efficiency, a phenomenon terme