Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Fatima Ezzahra, Bennani"'
1
Akademický článek
In Silico Identification of Promising New Pyrazole Derivative-Based Small Molecules for Modulating CRMP2, C-RAF, CYP17, VEGFR, C-KIT, and HDAC—Application towards Cancer Therapeutics
Autor: Fatima Ezzahra Bennani, Khalid Karrouchi, Latifa Doudach, Mario Scrima, Noor Rahman, Luca Rastrelli, Trina Ekawati Tallei, Christopher E. Rudd, My El Abbes Faouzi, M’hammed Ansar
Publikováno v: Current Issues in Molecular Biology, Vol 44, Iss 11, Pp 5312-5351 (2022)
Despite continual efforts being made with multiple clinical studies and deploying cutting-edge diagnostic tools and technologies, the discovery of new cancer therapies remains of severe worldwide concern. Multiple drug resistance has also emerged in
Externí odkaz: https://doaj.org/article/6e1daa3dfa014fd2ab03d3109669e8a1
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2
Akademický článek
Design and prediction of novel pyrazole derivatives as potential anti-cancer compounds based on 2D-QSAR study against PC-3, B16F10, K562, MDA-MB-231, A2780, ACHN and NUGC cancer cell lines
Autor: Fatima Ezzahra Bennani, Latifa Doudach, Khalid Karrouchi, Youssef El rhayam, Christopher E. Rudd, M’hammed Ansar, My El Abbes Faouzi
Publikováno v: Heliyon, Vol 8, Iss 8, Pp e10003- (2022)
Despite the decades of scientific studies for developing promising new therapies, cancer remains a major cause of illness and mortality, worldwide. Several cancer types are the major topic of research in drug discovery programs due to their global in
Externí odkaz: https://doaj.org/article/8661bc09f635410b929a88aa6b8d7a3c
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3
Akademický článek
Identification of New Drug Target in Staphylococcus lugdunensis by Subtractive Genomics Analysis and Their Inhibitors through Molecular Docking and Molecular Dynamic Simulation Studies
Autor: Yahya Alhamhoom, Umme Hani, Fatima Ezzahra Bennani, Noor Rahman, Md Abdur Rashid, Muhammad Naseer Abbas, Luca Rastrelli
Publikováno v: Bioengineering, Vol 9, Iss 9, p 451 (2022)
Staphylococcus lugdunensis is a coagulase-negative, Gram-positive, and human pathogenic bacteria. S. lugdunensis is the causative agent of diseases, such as native and prosthetic valve endocarditis, meningitis, septic arthritis, skin abscesses, brain
Externí odkaz: https://doaj.org/article/0e14f4331b4b4588ad1e216174e26d88
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6
Targeting EGFR, RSK1, RAF1, PARP2 and LIN28B for several cancer type therapies with newly synthesized pyrazole derivatives via a computational study
Autor: Fatima Ezzahra Bennani, Latifa Doudach, Khalid Karrouchi, Abdelilah Tarib, Christopher E Rudd, M’hammed Ansar, My El Abbes Faouzi
Publikováno v: Journal of biomolecular structuredynamics.
Cancer remains the leading cause of death in the world despite the significant advancements made in anticancer drug discovery. This study is aimed to computationally evaluate the efficacy of 63 in-house synthesized pyrazole derivatives targeted to bi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46405fd8e3614c7fc133e93950427699
https://pubmed.ncbi.nlm.nih.gov/35442150
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8
Design and prediction of novel pyrazole derivatives as potential anti-cancer compounds based on 2D-2D-QSAR study against PC-3, B16F10, K562, MDA-MB-231, A2780, ACHN and NUGC cancer cell lines
Autor: Fatima Ezzahra, Bennani, Latifa, Doudach, Khalid, Karrouchi, Youssef, El Rhayam, Christopher E, Rudd, M'hammed, Ansar, My, El Abbes Faouzi
Publikováno v: Heliyon. 8(8)
Despite the decades of scientific studies for developing promising new therapies, cancer remains a major cause of illness and mortality, worldwide. Several cancer types are the major topic of research in drug discovery programs due to their global in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::722c954d1bd58dd1da4d62af9dfb1896
https://pubmed.ncbi.nlm.nih.gov/35965973
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9
Overview of recent developments of pyrazole derivatives as an anticancer agent in different cell line
Autor: M'hammed Ansar, Khalid Karrouchi, Youssef Ramli, Latifa Doudach, My El Abbes Faouzi, Yahia Cherrah, Fatima Ezzahra Bennani
Publikováno v: Bioorganic chemistry. 97
Pyrazole is a five-membered aromatic heterocyclic ring with two adjacent nitrogen atoms C3H3N2H.The presence of this nucleus in pharmacological agents of various therapeutic categories gifts a broad spectrum of biological activities and pharmaceutica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b253512ce27d8b552c78d690568128
https://pubmed.ncbi.nlm.nih.gov/32120072
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10
Akademický článek
Synthesis, α-Glucosidase Inhibition, Anticancer, DFT and Molecular Docking Investigations of Pyrazole Hydrazone Derivatives.
Autor: Karrouchi, Khalid1 (AUTHOR), Sert, Yusuf2 (AUTHOR), Ansar, M'hammed3 (AUTHOR), Radi, Smaail4 (AUTHOR), El Bali, Brahim5 (AUTHOR), Imad, Rehan6 (AUTHOR), Alam, Anum6 (AUTHOR), Irshad, Rimsha6 (AUTHOR), Wajid, Sheeba7 (AUTHOR), Altaf, Muhammad7 (AUTHOR)
Publikováno v: Polycyclic Aromatic Compounds. 2023, Vol. 43 Issue 6, p5021-5040. 20p.
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