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pro vyhledávání: '"Fatima Dagher"'
Autor:
Song-hong Yang, Gabriel Tao, Liu Yang, Xiaohui Wu, Jing-wen Liu, Fatima Dagher, Shi-yi Ou, Yuan Song, Jun-qing Huang
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
Plant-based functional foods have attracted increasing research interest to validate their use in preventing metabolic disease. Since it is increasingly recognized that inflammation, oxidative stress, and circadian rhythm play vital roles in various
Externí odkaz:
https://doaj.org/article/f5960097c7fd4f23af6d6889ff93f63d
Neratinib causes non-recoverable gut injury and reduces intestinal cytochrome P450 3A enzyme in mice
Publikováno v:
Toxicol Res (Camb)
Neratinib is a pan-HER tyrosine kinase inhibitor newly approved by FDA in 2017 to treat HER2-positive breast cancer, but the phase III trial of neratinib showed that 96% of the patients taking neratinib experienced diarrhea. So far very few mechanist
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 166
Irinotecan is a first-line treatment for colorectal cancer and the prodrug of 7-ethyl-10-hydroxy-camptothecin (SN-38). However, its fatal gastrointestinal (GI) toxicity raises serious concern. In liver, irinotecan generates its inactive metabolite, S
Publikováno v:
Current Opinion in Toxicology. :36-40
The importance of oxidative stress has been increasingly recognized in diabetes and related cardiovascular complications as well as in chemical-induced toxicity, which makes it a potential therapeutic target for tackling such health issues. On the ot
Publikováno v:
Food and Chemical Toxicology. 171:113547