Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Fatiha El Hilali"'
Autor:
Mepur H. Ravindranath, Narendranath M. Ravindranath, Carly J. Amato-Menker, Fatiha El Hilali, Edward J. Filippone
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 6961-6985 (2024)
Human leukocyte antigens (HLAs) are polymorphic glycoproteins expressed on the cell surface of nucleated cells and consist of two classes, HLA class I and HLA class II. In contrast, in mice, these molecules, known as H-2, are expressed on both nuclea
Externí odkaz:
https://doaj.org/article/e2e4e2a4cabf4396a18bf0d2c8fe4705
Autor:
Mepur H. Ravindranath, Narendranath M. Ravindranath, Carly J. Amato-Menker, Fatiha El Hilali, Edward J. Filippone
Publikováno v:
Antibodies, Vol 13, Iss 1, p 8 (2024)
Previous investigators have used various anti-HLA-F monoclonal antibodies (mAbs) to demonstrate that the tissue distribution of HLA-F is highly restricted. Notably, these mAbs differed in their immunodiagnostic capabilities. Specifically, mAbs Fpep1.
Externí odkaz:
https://doaj.org/article/2d95fcd1c97d4429945aadd15821fbeb
Autor:
Mepur H. Ravindranath, Narendranath M. Ravindranath, Senthamil R. Selvan, Fatiha El Hilali, Carly J. Amato-Menker, Edward J. Filippone
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1178 (2023)
Cell surface HLA-I molecules (Face-1) consist of a polypeptide heavy chain (HC) with two groove domains (G domain) and one constant domain (C-domain) as well as a light chain, B2-microglobulin (B2m). However, HCs can also independently emerge unfolde
Externí odkaz:
https://doaj.org/article/0bdda8efb484481b832af4b6676d5c6a
Autor:
Mepur H. Ravindranath, Narendranath M. Ravindranath, Carly J. Amato-Menker, Fatiha El Hilali, Senthamil R. Selvan, Edward J. Filippone, Luis Eduardo Morales-Buenrostro
Publikováno v:
Antibodies, Vol 12, Iss 2, p 26 (2023)
Rheumatoid arthritis (RA) is a progressive, inflammatory, autoimmune, symmetrical polyarticular arthritis. It is characterized by synovial infiltration and activation of several types of immune cells, culminating in their apoptosis and antibody gener
Externí odkaz:
https://doaj.org/article/a5f8e98eb9814c169beb6628a9c6e688
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Transplantation (Tx) remains the optimal therapy for end-stage disease (ESD) of various solid organs. Although alloimmune events remain the leading cause of long-term allograft loss, many patients develop innate and adaptive immune responses leading
Externí odkaz:
https://doaj.org/article/eb4d6d66e3a445ce89eb19f61ecec5d6
Autor:
Mepur H. Ravindranath, Fatiha El Hilali, Carly J. Amato-Menker, Hajar El Hilali, Senthamil R. Selvan, Edward J. Filippone
Publikováno v:
Antibodies, Vol 11, Iss 3, p 58 (2022)
Cell-surface HLA-I molecules consisting of β2-microglobulin (β2m) associated heavy chains (HCs), referred to as Face-1, primarily present peptides to CD8+ T-cells. HCs consist of three α-domains, with selected amino acid sequences shared by all al
Externí odkaz:
https://doaj.org/article/e55fe62b87ca4ea286fcec34d58afc1e
Autor:
Mepur H. Ravindranath, Narendranath M. Ravindranath, Fatiha El Hilali, Senthamil R. Selvan, Edward J. Filippone
Publikováno v:
Antibodies, Vol 11, Iss 1, p 18 (2022)
Serum anti-HLA-I IgG are present in non-alloimmunized males, cancer patients, and transplant recipients. Anti-HLA-I antibodies are also present in intravenous immunoglobulin (IVIg), prepared from the plasma of thousands of healthy donors. However, th
Externí odkaz:
https://doaj.org/article/41d60baef0024a7ebc2dfee16fcfd8c2
Autor:
Mepur H. Ravindranath, Narendranath M. Ravindranath, Senthamil R. Selvan, Edward J. Filippone, Carly J. Amato-Menker, Fatiha El Hilali
Publikováno v:
Vaccines, Vol 10, Iss 2, p 339 (2022)
Leukocyte cell-surface HLA-I molecules, involved in antigen presentation of peptides to CD8+ T-cells, consist of a heavy chain (HC) non-covalently linked to β2-microglobulin (β2m) (Face-1). The HC amino acid composition varies across all six isofor
Externí odkaz:
https://doaj.org/article/51b17fce020445aaab6e33f8ba8e4abc
Publikováno v:
Vaccines, Vol 9, Iss 6, p 680 (2021)
HLA class-I (HLA-I) polyreactive monoclonal antibodies (mAbs) reacting to all HLA-I alleles were developed by immunizing mice with HLA-E monomeric, α-heavy chain (αHC) open conformers (OCs). Two mAbs (TFL-006 and TFL-007) were bound to the αHC’s
Externí odkaz:
https://doaj.org/article/13daf016388f4b2fab70011106ef93de
Autor:
Fatiha El Hilali, Sarah E. G. Porter, Hajar El Hilali, Hannah M. Meyls, Fatiha Laziri, Amorette Barber, Sarah A. Ghali, Noureddine Ouazzani
Publikováno v:
Mediterranean Journal of Nutrition and Metabolism. 13:89-100