Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Fatih Akkentli"'
Autor:
Fatih Akkentli, In kyu Jang, Yoonseop Choi, Young Min, Jinhee Park, Heejin Jo, Leoni Kim, Aashi Mendpara, Bikram Bains, Dongyoon Yoo, Jinchong Xu, Chan Hyun Na, Sung-Ung Kang
Publikováno v:
Frontiers in Dementia, Vol 3 (2024)
The aggregation of α-synuclein in the nervous system leads to a class of neurodegenerative disorders termed α-synucleinopathies. A form of primary degenerative dementia called Lewy body dementia (LBD) often develops when these aggregations develop
Externí odkaz:
https://doaj.org/article/4fe6441358824622b0d6592ef0af1d7f
Autor:
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S. Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J. Workman, Dario A. A. Vignali, Ulrike C. Muller, Cong Liu, Han Seok Ko, Valina L. Dawson, Ted M. Dawson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/59a521d03e984273bb3d708b36d570e9
Autor:
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S. Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J. Workman, Dario A. A. Vignali, Ulrike C. Muller, Cong Liu, Han Seok Ko, Valina L. Dawson, Ted M. Dawson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Pathologic α-synuclein (α-syn) spreads from cell-to-cell, in part, through binding to the lymphocyte-activation gene 3 (Lag3). Here we report that amyloid β precursor-like protein 1 (Aplp1) interacts with Lag3 that facilitates the binding
Externí odkaz:
https://doaj.org/article/a51c0a5470e944f6b5b546f3fa48e34f
Autor:
Fatih Akkentli, In kyu Jang, Yoonseop Choi, Dongyoon Yoo, Eric Joon-Hun Oh, Chan Hyun Na, Shinwon Ha, Sung-Ung Kang
The aggregation of α-synuclein in the nervous system leads to a class of neurodegenerative disorders termed α-synucleinopathies. A form of primary degenerative dementia called Lewy body dementia (LBD) often develops in the case these aggregations d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faa90a809b1e58aa651723b61701e88a
https://doi.org/10.1101/2022.10.10.511662
https://doi.org/10.1101/2022.10.10.511662
Autor:
Nikhil Panicker, Tae-In Kam, Hu Wang, Stewart Neifert, Shih-Ching Chou, Manoj Kumar, Saurav Brahmachari, Aanishaa Jhaldiyal, Jared T. Hinkle, Fatih Akkentli, Xiaobo Mao, Enquan Xu, Senthilkumar S. Karuppagounder, Eric T. Hsu, Sung-Ung Kang, Olga Pletnikova, Juan Troncoso, Valina L. Dawson, Ted M. Dawson
Publikováno v:
Neuron. 110(15)
Parkinson's disease (PD) is mediated, in part, by intraneuronal accumulation of α-synuclein aggregates andsubsequent death of dopamine (DA) neurons in the substantia nigra pars compacta (SNpc). Microglial hyperactivation of the NOD-like receptor pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71ad779e7f6589ab8ba8fc4d9514428
https://pubmed.ncbi.nlm.nih.gov/35926449
https://pubmed.ncbi.nlm.nih.gov/35926449
Autor:
Vassiliy Tsytsarev, Fatih Akkentli, Dmitri B. Papkovsky, Yu Chen, Elena Pumbo, Qinggong Tang, Reha S. Erzurumlu
Publikováno v:
Journal of Neuroscience Methods. 281:1-6
Background Brain imaging methods are continually improving. Imaging of the cerebral cortex is widely used in both animal experiments and charting human brain function in health and disease. Among the animal models, the rodent cerebral cortex has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37e6cc75bde199c8623cda8a6fbd251
https://doi.org/10.1016/j.jneumeth.2017.02.005
https://doi.org/10.1016/j.jneumeth.2017.02.005
Publikováno v:
Journal of Neurophysiology. 110:2627-2636
N-methyl-d-aspartate receptor (NMDAR)-mediated activity is required for whisker-related neural patterning in the rodent brain. Deletion of the essential NMDAR subunit NR1 gene in excitatory cortical neurons prevents whisker-specific barrel formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508c6bbee3e3d43f7249216fe2d3a648
https://doi.org/10.1152/jn.00052.2013
https://doi.org/10.1152/jn.00052.2013
Publikováno v:
American Journal of Biomedical Engineering. 2:212-217
Rotenone is a pesticide and piscicide, wh ich causes behavioral and biochemical changes in rats that closely resemble PD sympto ms in hu mans. Rotenone is a naturally occurring ret inoid plant ext ract derived fro m the roots of certain tropical and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a285a768e455db3a5ed4e4b928695c03
https://doi.org/10.5923/j.ajbe.20120206.01
https://doi.org/10.5923/j.ajbe.20120206.01
Autor:
Eric J. Nestler, Diana Simmons, Imran N. Alibhai, Scott Edwards, Fatih Akkentli, Erin B. Larson, David W. Self, Danielle Graham
Publikováno v:
Journal of Neurochemistry. 115:112-122
Chronic drug exposure induces alterations in gene expression profiles that are thought to underlie the development of drug addiction. The present study examined regulation of the Fos-family of transcription factors, specifically cFos, FosB, and ΔFos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff7fe4f4cd6ad856eaf31d2e19fab697
https://doi.org/10.1111/j.1471-4159.2010.06907.x
https://doi.org/10.1111/j.1471-4159.2010.06907.x
Autor:
Yu Chen, Reha S. Erzurumlu, Vassiliy Tsytsarev, Fatih Akkentli, Chia-Pin Liang, Qinggong Tang
Publikováno v:
Scientific Reports
The whisker system of rodents is an excellent model to study peripherally evoked neural activity in the brain. Discrete neural modules represent each whisker in the somatosensory cortex (“barrels”), thalamus (“barreloids”) and brain stem (“
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66eefa51f7c20d83bb7054385b296a8
https://doi.org/10.1038/srep17325
https://doi.org/10.1038/srep17325