Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Faten Zaibak"'
Autor:
Nicholas Matigian, Gary Brooke, Faten Zaibak, Tony Rossetti, Katarina Kollar, Rebecca Pelekanos, Celena Heazlewood, Alan Mackay-Sim, Christine A. Wells, Kerry Atkinson
Publikováno v:
Genomics Data, Vol 3, Iss C, Pp 70-74 (2015)
Multipotent mesenchymal stromal cells derived from human placenta (pMSCs), and unrestricted somatic stem cells (USSCs) derived from cord blood share many properties with human bone marrow-derived mesenchymal stromal cells (bmMSCs) and are currently i
Externí odkaz:
https://doaj.org/article/66d288f439d845699b93f00825ee64f4
Autor:
Robert Williamson, Faten Zaibak
Publikováno v:
Expert Review of Respiratory Medicine. 2:1-5
Autor:
Suthat Fucharoen, Kerry J. Fowler, Faten Zaibak, Duangporn Jamsai, Robert Williamson, Jim Vadolas, Sophie Gazeas, Wantana Khongnium, Panayiotis A. Ioannou, Lucille Voullaire
Publikováno v:
Genomics. 85:453-461
Accurate animal models that recapitulate the phenotype and genotype of patients with beta-thalassemia would enable the development of a range of possible therapeutic approaches. Here we report the generation of a mouse model carrying the codons 41-42
Autor:
Hady Wardan, Lucille Voullaire, Jim Vadolas, Michael Orford, Faten Zaibak, Panayiotis A. Ioannou, Robert Williamson
Publikováno v:
Blood. 100:4209-4216
Reactivation of fetal hemoglobin genes has been proposed as a potential therapeutic procedure in patients with beta-thalassemia, sickle cell disease, or other beta-hemoglobinopathies. In vitro model systems based on small plasmid globin gene construc
Autor:
Jenny Kozlovski, Faten Zaibak, Caitlin E. Filby, Robert Williamson, Ngaire Elwood, Peter van Kooy
Publikováno v:
C59. STEM CELLS, PROGENITOR CELLS AND TISSUE REGENERATION.
Publikováno v:
Gene therapy. 16(3)
Stem cells from a patient with a genetic disease could be used for cell therapy if it were possible to insert a functional copy of the defective gene. In this study, we investigate the transfection and subsequent integration of large genomic fragment
Autor:
Faten Zaibak, Lucille Voullaire, Hady Wardan, Duangporn Jamsai, Marco Bosmans, Jim Vadolas, Robert Williamson, Panos A. Ioannou
Publikováno v:
Biochimica et biophysica acta. 1728(3)
We report the generation and characterisation of the first transgenic mice exclusively expressing normal human beta-globin ((hu)beta-globin) from a 183 kb genomic fragment. Four independent lines were generated, each containing 2-6 copies of the (hu)
Autor:
Hady Wardan, Kim Simpfendorfer, Keith Al-Hasani, Jim Vadolas, Ricardo Villain, Panayiotis A. Ioannou, Faten Zaibak
Publikováno v:
Plasmid. 49(2)
Bacterial artificial chromosome (BAC) cloning systems currently in use generate high quality genomic libraries for gene mapping, identification, and sequencing. However, the most commonly used BAC cloning systems do not facilitate functional studies
Autor:
Michael Orford, Panayiotis A. Ioannou, Mikhail Nefedov, Faten Zaibak, Jim Vadolas, Robert Williamson
GET Recombination, a simple inducible homologous recombination system for Escherichia coli, was used to target insertion of an EGFP cassette between the start and termination codons of the beta-globin gene in a 200 kb BAC clone. The high degree of ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d46a89e77ed6d343f5a78b129f7f9c
https://europepmc.org/articles/PMC110756/
https://europepmc.org/articles/PMC110756/
Unrestricted somatic stem cells from human umbilical cord blood grow in serum-free medium as spheres
Autor:
Paul Bello, Faten Zaibak, Robert Williamson, Haozhi Ang, Duncan E. Crombie, Mirella Dottori, Jennifer Kozlovski
Publikováno v:
BMC Biotechnology
BMC Biotechnology, Vol 9, Iss 1, p 101 (2009)
BMC Biotechnology, Vol 9, Iss 1, p 101 (2009)
Background Human umbilical cord blood-derived unrestricted somatic stem cells (USSCs), which are capable of multilineage differentiation, are currently under investigation for a number of therapeutic applications. A major obstacle to their clinical u