Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Faten Sliman"'
Publikováno v:
مجلة جامعة تشرين للدراسات والبحوث العلمية، سلسلة العلوم الصحية, Vol 44, Iss 6 (2023)
يعد التكافؤ الحيوي شرطاً أساسياً للتبديل بين الدواء الأصيل والأدوية الجنيسة، ويتم تقييمه إمّا في الجسم الحي أو في الزجاج. يجب أن يتم اختب
Externí odkaz:
https://doaj.org/article/b02a1065970b414396c8f92b859ab109
Publikováno v:
مجلة جامعة تشرين للدراسات والبحوث العلمية، سلسلة العلوم الصحية, Vol 43, Iss 6 (2022)
تزايد الاهتمام مؤخراً بالكيمياء الخضراء وأصبح البحث عن بدائل للمواد الضارّة للبيئة حاجةً لابدّ منها، وهنا ظهرت النباتات كمصدر متجدّد لل
Externí odkaz:
https://doaj.org/article/4c6c7b06d5b54cd9804b067f3b4d418c
Publikováno v:
International Journal of Organic Chemistry. 11:106-127
The serine/threonine Akt kinase signaling pathway plays an essential role not only in tumorigenesis but also in the potential response to anticancer therapeutic agents. Therefore, aiming to identify potent and selective Akt inhibitors, a novel series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0ae36cf508728af351c899f1099fe47
https://doi.org/10.4236/ijoc.2021.113009
https://doi.org/10.4236/ijoc.2021.113009
Publikováno v:
International Journal of Organic Chemistry. 11:72-89
CDK2 is one of the most important members of Cyclin-dependent kinases. It is a critical modulator of various oncogenic signaling pathways, and its activity is vital for loss of proliferative control during oncogenesis. This work has focused on develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::955c67997ddc408d9676a1c573ffcb97
https://doi.org/10.4236/ijoc.2021.112007
https://doi.org/10.4236/ijoc.2021.112007
Publikováno v:
Research Journal of Pharmacy and Technology. 12:5413
Pim-1 (Proviral Insertion site of Molony Murine Leukemia virus) kinases is an oncogene which is known to be over expressed and dysregulated in hematological and solid tumors suggesting that inhibition of Pim-1 signaling could provide patients with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::409d8c7970cda6204a017e8fe5d89de6
https://doi.org/10.5958/0974-360x.2019.00939.9
https://doi.org/10.5958/0974-360x.2019.00939.9
Autor:
Faten Sliman, Samar Alnukari
Publikováno v:
Research Journal of Pharmacy and Technology. 12:2999
Protein kinase, especially tyrosine kinase Src, is considered as an important target for cancer therapy such as lung, prostate and central nervous system cancers, as well as its involvement in tumor metastasis. The aim of this study was to find effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6ef161f9d7621cdff91d7a76e164f84
https://doi.org/10.5958/0974-360x.2019.00507.9
https://doi.org/10.5958/0974-360x.2019.00507.9
Autor:
Philippe M. Loiseau, Faten Sliman, Saumya Srivastava, Surendra Puri, Didier Desmaële, Aditya Verma, Marie Normand-Bayle, Suman Gupta
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:1777-1780
A series of 9 quinolines and 18 styrylquinolines was evaluated for the drugs' in vitro antileishmanial activities and cytotoxicities. The 7-aroylstyrylquinoline scaffold appeared to be the most promising one, with the most interesting compound, no. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff9abbf59e1d7f1cd27a3202aa34802
https://doi.org/10.1128/aac.01299-10
https://doi.org/10.1128/aac.01299-10
Autor:
Didier Desmaële, Faten Sliman
Publikováno v:
Synthesis. 2010:619-630
A series of 5-aryl- and 5-heteroaryl-7-carboxyl-8-hydroxyquinaldines were prepared from 5-bromo-7-methoxycarbonyl-8-benzyloxyquinaldine based on the Suzuki cross-coupling reaction using potassium organotrifluoroborates. An efficient method of deprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ce539836e34eb8c3c5580013bfeff0a
https://doi.org/10.1055/s-0029-1218585
https://doi.org/10.1055/s-0029-1218585
Autor:
Didier Desmaële, Faten Sliman
Publikováno v:
ChemInform. 41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f83400bbfd0a6c8814175b265b657937
https://doi.org/10.1002/chin.201025134
https://doi.org/10.1002/chin.201025134
Autor:
Laurent Meijer, Mélina Blairvacq, Faten Sliman, Didier Desmaële, Jordi Rodrigo, Emilie Durieu
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(9)
Pim-1 kinase is a cytoplasmic serine/threonine kinase that controls programmed cell death by phosphorylating substrates that regulate both apoptosis and cellular metabolism. A series of 2-styrylquinolines and quinoline-2-carboxamides has been identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11976a4b8893209f0f549bd27d97a960
https://pubmed.ncbi.nlm.nih.gov/20363627
https://pubmed.ncbi.nlm.nih.gov/20363627