Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Faten Shaeib"'
Autor:
Mili Thakur, Faten Shaeib, Sana N. Khan, Hamid-Reza Kohan-Ghadr, Roohi Jeelani, Sarah R. Aldhaheri, Bernard Gonik, Husam M. Abu-Soud
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Premature ovarian insufficiency (POI) is a frequent long-term complication of classic galactosemia. The majority of women with this disorder develop POI, however rare spontaneous pregnancies have been reported. Here, we evaluate the effect o
Externí odkaz:
https://doaj.org/article/5427e97d91134a08bf3b54cec9df41c0
Autor:
Faten Shaeib, Sana N Khan, Mili Thakur, Hamid-Reza Kohan-Ghadr, Sascha Drewlo, Ghassan M Saed, Subramaniam Pennathur, Husam M Abu-Soud
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151160 (2016)
Myeloperoxidase (MPO), an abundant heme-containing enzyme present in neutrophils, monocytes, and macrophages, is produced in high levels during inflammation, and associated with poor reproductive outcomes. MPO is known to generate hypochlorous acid (
Externí odkaz:
https://doaj.org/article/e65ed48692764f0eb060f45fe889aee6
Autor:
Sana N Khan, Faten Shaeib, Tohid Najafi, Mahendra Kavdia, Bernard Gonik, Ghassan M Saed, Pravin T Goud, Husam M Abu-Soud
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132388 (2015)
Hydrogen peroxide (H2O2) is a relatively long-lived signaling molecule that plays an essential role in oocyte maturation, implantation, as well as early embryonic development. Exposure to relatively high levels of H2O2 functions efficiently to accele
Externí odkaz:
https://doaj.org/article/3e01c96eac504e9fb9403bf640036ca2
Autor:
Faten Shaeib, Sana N Khan, Iyad Ali, Tohid Najafi, Dhiman Maitra, Ibrahim Abdulhamid, Ghassan M Saed, Subramaniam Pennathur, Husam M Abu-Soud
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120737 (2015)
Myeloperoxidase (MPO) generated hypochlorous acid (HOCl) formed during catalysis is able to destroy the MPO heme moiety through a feedback mechanism, resulting in the accumulation of free iron. Here we show that the presence of melatonin (MLT) can pr
Externí odkaz:
https://doaj.org/article/96a78c36047442b8973884c033838ac5
Autor:
Dhiman Maitra, Iyad Ali, Rasha M Abdulridha, Faten Shaeib, Sana N Khan, Ghassan M Saed, Subramaniam Pennathur, Husam M Abu-Soud
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e110595 (2014)
Hypochlorous acid (HOCl) is a potent oxidant generated by myeloperoxidase (MPO), which is an abundant enzyme used for defense against microbes. We examined the potential role of HOCl in corrin ring destruction and subsequent formation of cyanogen chl
Externí odkaz:
https://doaj.org/article/1a39001e398c4f2cac7582f1663e0f1a
Autor:
Faten Shaeib, Tohid Najafi, Hamid Reza Kohan-Ghadr, Husam M. Abu-Soud, Sana N. Khan, Mili Thakur, Roohi Jeelani, Robert T. Morris, Sarah R. Aldhaheri
Publikováno v:
Free Radical Biology and Medicine. 110:11-18
Cyclophosphamide (CTX) is a chemotherapeutic agent widely used to treat ovarian, breast, and hematological cancers as well as autoimmune disorders. Such chemotherapy is associated with reproductive failure and premature ovarian insufficiency. The mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794bc12ac165fd62ce90229e66d49c9e
https://doi.org/10.1016/j.freeradbiomed.2017.05.006
https://doi.org/10.1016/j.freeradbiomed.2017.05.006
Autor:
Awoniyi O. Awonuga, Husam M. Abu-Soud, Mili Thakur, Jashoman Banerjee, Sana N. Khan, Jing Dai, Iyad Ali, M.G. Saed, Faten Shaeib
Publikováno v:
Reproductive Sciences. 23:498-507
We investigated the ability of reactive oxygen species (ROS), such as hydrogen peroxide (H(2)O(2)), hydroxyl radical ((·)OH), and hypochlorous acid (HOCl), to overcome the defensive capacity of cumulus cells and elucidate the mechanism through which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80bb41a1eedd2ad05840170ef0be9de8
https://doi.org/10.1177/1933719115607993
https://doi.org/10.1177/1933719115607993
Autor:
Faten Shaeib, Mili Thakur, Roohi Jeelani, Awoniyi O. Awonuga, Pravin T. Goud, Sana N. Khan, Husam M. Abu-Soud
Publikováno v:
Free Radical Biology and Medicine. 91:275-280
Previous theoretical studies have suggested that utilization of 3-D imaging to acquire morphologic parameters of meiotic spindles may be useful in infertility related procedures as an assessment of oocyte quality. However, our results show that treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed4d6a8b1bd9dab2286596afaf29c9f
https://doi.org/10.1016/j.freeradbiomed.2015.12.033
https://doi.org/10.1016/j.freeradbiomed.2015.12.033
Autor:
Bernard Gonik, Mili Thakur, Roohi Jeelani, Sana N. Khan, Hamid Reza Kohan-Ghadr, Sarah R. Aldhaheri, Husam M. Abu-Soud, Faten Shaeib
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Premature ovarian insufficiency (POI) is a frequent long-term complication of classic galactosemia. The majority of women with this disorder develop POI, however rare spontaneous pregnancies have been reported. Here, we evaluate the effect of D-galac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe660ec456f7616dad376cfdb40a140
https://doi.org/10.1038/s41598-017-00159-y
https://doi.org/10.1038/s41598-017-00159-y
Autor:
Michael P. Diamond, Zhe Yang, Ghassan M. Saed, Dhiman Maitra, Ibrahim Abdulhamid, Jaeman Byun, Subramaniam Pennathur, Sana N. Khan, Faten Shaeib, Husam M. Abu-Soud, Peter R. Andreana
Publikováno v:
Journal of Inorganic Biochemistry. 140:245-254
Myeloperoxidase (MPO), lactoperoxidase (LPO) and eosinophil peroxidase (EPO) play a central role in oxidative damage in inflammatory disorders by utilizing hydrogen peroxide and halides/pseudo halides to generate the corresponding hypohalous acid. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90333ca421d97c6d9f2ed7baf359e68
https://doi.org/10.1016/j.jinorgbio.2014.06.018
https://doi.org/10.1016/j.jinorgbio.2014.06.018