Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Fatemeh Shokraie"'
Autor:
Christin Riess, Björn Schneider, Hanna Kehnscherper, Julia Gesche, Nina Irmscher, Fatemeh Shokraie, Carl Friedrich Classen, Elisa Wirthgen, Grazyna Domanska, Annette Zimpfer, Daniel Strüder, Christian Junghanss, Claudia Maletzki
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO2) are the key enzymes of tryptophan (TRP) metabolism in the kynurenine pathway (KP). Both enzymes function as indicators of immunosuppression and poor survival in cancer patients.
Externí odkaz:
https://doaj.org/article/84a6ad70899d454bb54e3837a71f103e
Autor:
Christin Riess, Fatemeh Shokraie, Carl Friedrich Classen, Bernd Kreikemeyer, Tomas Fiedler, Christian Junghanss, Claudia Maletzki
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 2, Pp 854-870 (2018)
Arginine auxotrophy occurs in certain tumor types and is usually caused by the silencing of argininosuccinate synthetase 1 or arginine lyase genes. Such tumors are often associated with an intrinsic chemoresistance and thus a poor prognosis. Arginine
Externí odkaz:
https://doaj.org/article/07deca83d7ef459f8c6b4a08e663e55f
Autor:
Claudia Maletzki, Christin Riess, Carl Friedrich Classen, Fatemeh Shokraie, Tomas Fiedler, Bernd Kreikemeyer, Christian Junghanss
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 2, Pp 854-870 (2018)
Arginine auxotrophy occurs in certain tumor types and is usually caused by the silencing of argininosuccinate synthetase 1 or arginine lyase genes. Such tumors are often associated with an intrinsic chemoresistance and thus a poor prognosis. Arginine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e56025b20137a38a52383a6a5aca851
https://pubmed.ncbi.nlm.nih.gov/30466103
https://pubmed.ncbi.nlm.nih.gov/30466103
Autor:
Tomas Fiedler, Claudia Maletzki, Björn Schneider, Carl Friedrich Classen, Christin Riess, Fatemeh Shokraie
Publikováno v:
Neuro-Oncology. 20:i95-i96
Arginine auxotrophy constitutes a metabolic defect that renders tumors susceptible towards arginine-depleting substances, such as bacterial arginine deiminase (ADI). In our previous studies, Arg auxotrophy and thus ADI-susceptibility was confirmed on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2f70b149fae8e78659ce4314c0aab7
https://doi.org/10.1093/neuonc/noy059.304
https://doi.org/10.1093/neuonc/noy059.304